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1-Methyl-4-phenylpyridinium

"1-Methyl-4-phenylpyridinium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.


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This graph shows the total number of publications written about "1-Methyl-4-phenylpyridinium" by people in this website by year, and whether "1-Methyl-4-phenylpyridinium" was a major or minor topic of these publications.
Bar chart showing 16 publications over 12 distinct years, with a maximum of 4 publications in 2003
To see the data from this visualization as text, click here.
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