Reperfusion Injury

"Reperfusion Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.

Descriptor ID	D015427
MeSH Number(s)	C14.907.725 C23.550.767.877
Concept/Terms	Reperfusion Injury Reperfusion Injury Reperfusion Damage Damage, Reperfusion Damages, Reperfusion Reperfusion Damages Ischemia-Reperfusion Injury Ischemia Reperfusion Injury Injury, Ischemia-Reperfusion Injuries, Ischemia-Reperfusion Injury, Ischemia Reperfusion Ischemia-Reperfusion Injuries Injury, Reperfusion Injuries, Reperfusion Reperfusion Injuries

Below are MeSH descriptors whose meaning is more general than "Reperfusion Injury".

Diseases [C]
Cardiovascular Diseases [C14]
Vascular Diseases [C14.907]
Reperfusion Injury [C14.907.725]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Postoperative Complications [C23.550.767]
Reperfusion Injury [C23.550.767.877]

Below are MeSH descriptors whose meaning is related to "Reperfusion Injury".

Below are MeSH descriptors whose meaning is more specific than "Reperfusion Injury".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Reperfusion Injury" by people in this website by year, and whether "Reperfusion Injury" was a major or minor topic of these publications.

Bar chart showing 52 publications over 25 distinct years, with a maximum of 5 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	2	0	2
2001	1	0	1
2002	2	1	3
2003	0	1	1
2004	1	2	3
2005	1	0	1
2006	2	1	3
2007	0	3	3
2008	1	2	3
2009	1	3	4
2010	3	1	4
2011	1	0	1
2012	1	1	2
2013	2	0	2
2014	1	0	1
2015	1	0	1
2016	1	0	1
2018	4	1	5
2019	1	0	1
2020	1	1	2
2021	1	1	2
2022	2	0	2
2023	2	0	2
2025	1	0	1

Below are the most recent publications written about "Reperfusion Injury" by people in Profiles.

Bai Y, Ren H, Leng S, Yuan M, Jiang Y, Zhang S, Wang Y, Ju M, Wang Z, Xi W, Xu L, Zheng B, Li D, Huo X, Zhu T, Zhang B, Shen L, Zhang Y, Jiang W, Zhang JH, Han B, Yao H. CD8+GZMK+CD27+CCR7+ T cells mobilized by splenic sympathetic nerves aggravate brain ischemia?reperfusion injury via CCL19-positive endothelial cells. Cell Mol Immunol. 2025 Sep; 22(9):1061-1076.

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Kawasaki NK, Suhara T, Komai K, Shimada BK, Yorichika N, Kobayashi M, Baba Y, Higa JK, Matsui T. The role of ferroptosis in cell-to-cell propagation of cell death initiated from focal injury in cardiomyocytes. Life Sci. 2023 Nov 01; 332:122113.

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Li ZL, Ding L, Ma RX, Zhang Y, Zhang YL, Ni WJ, Tang TT, Wang GH, Wang B, Lv LL, Wu QL, Wen Y, Liu BC. Activation of HIF-1a C-terminal transactivation domain protects against hypoxia-induced kidney injury through hexokinase 2-mediated mitophagy. Cell Death Dis. 2023 05 24; 14(5):339.

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Chen J, Tang TT, Cao JY, Li ZL, Zhong X, Wen Y, Shen AR, Liu BC, Lv LL. KIM-1 augments hypoxia-induced tubulointerstitial inflammation through uptake of small extracellular vesicles by tubular epithelial cells. Mol Ther. 2023 05 03; 31(5):1437-1450.

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Chen WN, Shaikh MF, Bhuvanendran S, Date A, Ansari MT, Radhakrishnan AK, Othman I. Poloxamer 188 (P188), A Potential Polymeric Protective Agent for Central Nervous System Disorders: A Systematic Review. Curr Neuropharmacol. 2022; 20(4):799-808.

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Tang TT, Wang B, Li ZL, Wen Y, Feng ST, Wu M, Liu D, Cao JY, Yin Q, Yin D, Fu YQ, Gao YM, Ding ZY, Qian JY, Wu QL, Lv LL, Liu BC. Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI. J Am Soc Nephrol. 2021 10; 32(10):2467-2483.

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Cao JY, Wang B, Tang TT, Wen Y, Li ZL, Feng ST, Wu M, Liu D, Yin D, Ma KL, Tang RN, Wu QL, Lan HY, Lv LL, Liu BC. Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury. Theranostics. 2021; 11(11):5248-5266.

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Han SJ, Williams RM, D'Agati V, Jaimes EA, Heller DA, Lee HT. Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury. Kidney Int. 2020 07; 98(1):76-87.

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Zhang P, Li Y, Fu Y, Huang L, Liu B, Zhang L, Shao XM, Xiao D. Inhibition of Autophagy Signaling via 3-methyladenine Rescued Nicotine-Mediated Cardiac Pathological Effects and Heart Dysfunctions. Int J Biol Sci. 2020; 16(8):1349-1362.

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Kobayashi M, Higa JK, Matsui T. The role of ubiquitin in cardiac ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2019 Mar 01; 316(3):H583-H585.

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