"Thymus Gland" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.
| Descriptor ID |
D013950
|
| MeSH Number(s) |
A10.549.750 A15.382.520.604.750
|
| Concept/Terms |
Thymus Gland- Thymus Gland
- Gland, Thymus
- Glands, Thymus
- Thymus Glands
- Thymus
|
Below are MeSH descriptors whose meaning is more general than "Thymus Gland".
Below are MeSH descriptors whose meaning is more specific than "Thymus Gland".
This graph shows the total number of publications written about "Thymus Gland" by people in this website by year, and whether "Thymus Gland" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 |
| 1992 | 1 | 0 | 1 |
| 1993 | 1 | 1 | 2 |
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 3 | 6 |
| 2001 | 3 | 1 | 4 |
| 2002 | 1 | 1 | 2 |
| 2003 | 3 | 2 | 5 |
| 2004 | 4 | 1 | 5 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 3 | 5 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thymus Gland" by people in Profiles.
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Sullivan KE. Chromosome 22q11.2 deletion syndrome and DiGeorge syndrome. Immunol Rev. 2019 01; 287(1):186-201.
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Kucerová-Levisohn M, Knirr S, Mejia RI, Ortiz BD. The 3'-Ja Region of the TCRa Locus Bears Gene Regulatory Activity in Thymic and Peripheral T Cells. PLoS One. 2015; 10(7):e0132856.
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Guyden JC, Martinez M, Chilukuri RV, Reid V, Kelly F, Samms MO. Thymic Nurse Cells Participate in Heterotypic Internalization and Repertoire Selection of Immature Thymocytes; Their Removal from the Thymus of Autoimmune Animals May be Important to Disease Etiology. Curr Mol Med. 2015; 15(9):828-35.
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Osada M, Singh VJ, Wu K, Sant'Angelo DB, Pezzano M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS One. 2013; 8(12):e83024.
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Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S. IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol. 2011 Dec 15; 187(12):6335-45.
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Sivaraman V, Zhang L, Su L. Type I interferon contributes to CD4+ T cell depletion induced by infection with HIV-1 in the human thymus. J Virol. 2011 Sep; 85(17):9243-6.
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Killebrew JR, Perdue N, Kwan A, Thornton AM, Shevach EM, Campbell DJ. A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease. J Immunol. 2011 Jul 15; 187(2):861-9.
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Lv H, Havari E, Pinto S, Gottumukkala RV, Cornivelli L, Raddassi K, Matsui T, Rosenzweig A, Bronson RT, Smith R, Fletcher AL, Turley SJ, Wucherpfennig K, Kyewski B, Lipes MA. Impaired thymic tolerance to a-myosin directs autoimmunity to the heart in mice and humans. J Clin Invest. 2011 Apr; 121(4):1561-73.
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Rafie C, Campa A, Smith S, Huffman F, Newman F, Baum MK. Cocaine reduces thymic endocrine function: another mechanism for accelerated HIV disease progression. AIDS Res Hum Retroviruses. 2011 Aug; 27(8):815-22.
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Knirr S, Gomos-Klein J, Andino BE, Harrow F, Erhard KF, Kovalovsky D, Sant'Angelo DB, Ortiz BD. Ectopic T cell receptor-a locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once. PLoS One. 2010 Nov 22; 5(11):e15527.