Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
| Descriptor ID |
D011942
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.300 D12.776.543.750.695.150.300.300 D12.776.543.750.720.330.300.300
|
| Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
- Receptor, Adrenergic, alpha
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Arencibia-Albite F, Paladini C, Williams JT, Jim?nez-Rivera CA. Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area. Neuroscience. 2007 Oct 26; 149(2):303-14.
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Wang XM, Zhang ZJ, Bains R, Mokha SS. Effect of antisense knock-down of alpha(2a)- and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat. Pain. 2002 Jul; 98(1-2):27-35.
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Zhang KM, Wang XM, Peterson AM, Chen WY, Mokha SS. alpha2-adrenoceptors modulate NMDA-evoked responses of neurons in superficial and deeper dorsal horn of the medulla. J Neurophysiol. 1998 Oct; 80(4):2210-4.
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Christ GJ, Schwartz CB, Stone BA, Parker M, Janis M, Gondre M, Valcic M, Melman A. Kinetic characteristics of alpha 1-adrenergic contractions in human corpus cavernosum smooth muscle. Am J Physiol. 1992 Jul; 263(1 Pt 2):H15-9.
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Hamilton CA, Yakubu MA, Howie CA, Reid JL. Do centrally-acting antihypertensive drugs act at non-adrenergic as well as alpha-2 adrenoceptor sites? Clin Exp Hypertens A. 1992; 14(5):815-35.
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Piletz JE, Halaris A, Saran A, Marler MR. Desipramine lowers tritiated para-aminoclonidine binding in platelets of depressed patients. Arch Gen Psychiatry. 1991 Sep; 48(9):813-20.
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Piletz JE, Andorn AC, Unnerstall JR, Halaris A. Binding of [3H]-p-aminoclonidine to alpha 2-adrenoceptor states plus a non-adrenergic site on human platelet plasma membranes. Biochem Pharmacol. 1991 Jul 15; 42(3):569-84.
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Piletz JE, Sarasua M, Chotani M, Saran A, Halaris A. Relationship between membrane fluidity and adrenoceptor binding in depression. Psychiatry Res. 1991 Jul; 38(1):1-12.
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Clark JT. Suppression of copulatory behavior in male rats following central administration of clonidine. Neuropharmacology. 1991 Apr; 30(4):373-82.
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Ward WS, Coffey DS. Specific organization of genes in relation to the sperm nuclear matrix. Biochem Biophys Res Commun. 1990 Nov 30; 173(1):20-5.