Purkinje Cells

"Purkinje Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The output neurons of the cerebellar cortex.

Descriptor ID	D011689
MeSH Number(s)	A08.186.211.132.810.428.200.212.600 A08.675.784 A11.671.784
Concept/Terms	Purkinje Cells Purkinje Cells Cells, Purkinje Purkinje Neuron Neuron, Purkinje Neurons, Purkinje Purkinje Neurons Purkyne Cell Cell, Purkyne Cells, Purkyne Purkyne Cells Purkinje Cell Cell, Purkinje

Below are MeSH descriptors whose meaning is more general than "Purkinje Cells".

Anatomy [A]
Nervous System [A08]
Central Nervous System [A08.186]
Brain [A08.186.211]
Brain Stem [A08.186.211.132]
Rhombencephalon [A08.186.211.132.810]
Metencephalon [A08.186.211.132.810.428]
Cerebellum [A08.186.211.132.810.428.200]
Cerebellar Cortex [A08.186.211.132.810.428.200.212]
Purkinje Cells [A08.186.211.132.810.428.200.212.600]
Neurons [A08.675]
Purkinje Cells [A08.675.784]
Cells [A11]
Neurons [A11.671]
Purkinje Cells [A11.671.784]

Below are MeSH descriptors whose meaning is more specific than "Purkinje Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Purkinje Cells" by people in this website by year, and whether "Purkinje Cells" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 2 publications in 2002 and 2004 and 2006 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2002	1	1	2
2004	2	0	2
2005	1	0	1
2006	2	0	2
2007	1	0	1
2008	1	0	1
2009	1	0	1
2011	2	0	2
2016	1	0	1
2019	1	0	1
2023	1	0	1
2025	0	1	1

Below are the most recent publications written about "Purkinje Cells" by people in Profiles.

Rodichkin AN, Brown AM, Devabathini P, McGlothan JL, Chen S, Pattammattel A, Chu YS, Lin T, Pontow DD, Abilmouna K, Kapoor R, Hardin SE, Pushkar Y, Sillitoe RV, Guilarte TR. Cerebellar dysfunction in a mouse model of childhood-onset manganese-induced dystonia parkinsonism. Neurobiol Dis. 2025 11; 216:107115.

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Kim S, Ochoa K, Melli SE, Yousufzai FAK, Barrera ZD, Williams AA, McIntyre G, Delgado E, Bolish JN, Macleod CM, Boghos M, Lens HP, Ramos AG, Wilson VB, Maloney K, Padron ZM, Khan AH, Blanco RE, Soto I. Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease. Sci Rep. 2023 04 06; 13(1):5665.

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Kavetsky L, Green KK, Boyle BR, Yousufzai FAK, Padron ZM, Melli SE, Kuhnel VL, Jackson HM, Blanco RE, Howell GR, Soto I. Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C. Sci Rep. 2019 10 11; 9(1):14722.

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Yang Z, Santamaria F. Purkinje cell intrinsic excitability increases after synaptic long term depression. J Neurophysiol. 2016 09 01; 116(3):1208-17.

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Nichols RA. Serotonin, presynaptic 5-HT3 receptors and synaptic plasticity in the developing cerebellum. J Physiol. 2011 Nov 01; 589(Pt 21):5019-20.

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Santamaria F, Wils S, De Schutter E, Augustine GJ. The diffusional properties of dendrites depend on the density of dendritic spines. Eur J Neurosci. 2011 Aug; 34(4):561-8.

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Kreiner L, Christel CJ, Benveniste M, Schwaller B, Lee A. Compensatory regulation of Cav2.1 Ca2+ channels in cerebellar Purkinje neurons lacking parvalbumin and calbindin D-28k. J Neurophysiol. 2010 Jan; 103(1):371-81.

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Ford GD, Ford BD, Steele EC, Gates A, Hood D, Matthews MAB, Mirza S, MacLeish PR. Analysis of transcriptional profiles and functional clustering of global cerebellar gene expression in PCD3J mice. Biochem Biophys Res Commun. 2008 Dec 12; 377(2):556-561.

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Tanaka K, Khiroug L, Santamaria F, Doi T, Ogasawara H, Ellis-Davies GC, Kawato M, Augustine GJ. Ca2+ requirements for cerebellar long-term synaptic depression: role for a postsynaptic leaky integrator. Neuron. 2007 Jun 07; 54(5):787-800.

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Santamaria F, Wils S, De Schutter E, Augustine GJ. Anomalous diffusion in Purkinje cell dendrites caused by spines. Neuron. 2006 Nov 22; 52(4):635-48.

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