"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
Descriptor ID |
D011519
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MeSH Number(s) |
G05.360.340.024.340.375.500.791
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".
- Proto-Oncogenes
- Genes, abl
- Genes, bcl-1
- Genes, bcl-2
- Genes, erbA
- Genes, erbB
- Genes, fms
- Genes, fos
- Genes, jun
- Genes, mos
- Genes, myb
- Genes, myc
- Genes, ras
- Genes, rel
- Genes, sis
- Genes, src
This graph shows the total number of publications written about "Proto-Oncogenes" by people in this website by year, and whether "Proto-Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
2001 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.
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Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, Wang J, Erdjument-Bromage H, Tempst P, Cordon-Cardo C, Pandolfi PP, Jiang X. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell. 2007 Jan 12; 128(1):129-39.
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Pegram MD, Pietras R, Bajamonde A, Klein P, Fyfe G. Targeted therapy: wave of the future. J Clin Oncol. 2005 Mar 10; 23(8):1776-81.
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Rulli SJ, Louneva NM, Skripnikova EV, Rabon EC. Site-directed mutagenesis of cation coordinating residues in the gastric H,K-ATPase. Arch Biochem Biophys. 2001 Mar 01; 387(1):27-34.
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Feinstein PG, Kornfeld K, Hogness DS, Mann RS. Identification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue. Genetics. 1995 Jun; 140(2):573-86.
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Shiramizu B, Herndier BG, McGrath MS. Identification of a common clonal human immunodeficiency virus integration site in human immunodeficiency virus-associated lymphomas. Cancer Res. 1994 Apr 15; 54(8):2069-72.
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Urven LE, Weng DE, Schumaker AL, Gearhart JD, McCarrey JR. Differential gene expression in fetal mouse germ cells. Biol Reprod. 1993 Mar; 48(3):564-74.
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Lin TP, Guzman RC, Osborn RC, Thordarson G, Nandi S. Role of endocrine, autocrine, and paracrine interactions in the development of mammary hyperplasia in Wnt-1 transgenic mice. Cancer Res. 1992 Aug 15; 52(16):4413-9.
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Reddy ES, Rao VN. erg, an ets-related gene, codes for sequence-specific transcriptional activators. Oncogene. 1991 Dec; 6(12):2285-9.
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Hipskind RA, Rao VN, Mueller CG, Reddy ES, Nordheim A. Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF. Nature. 1991 Dec 19-26; 354(6354):531-4.
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Reddy ES, Rao VN. Localization and modulation of the DNA-binding activity of the human c-ets-1 protooncogene. Cancer Res. 1990 Aug 15; 50(16):5013-6.