"NAD" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
| Descriptor ID |
D009243
|
| MeSH Number(s) |
D03.633.100.759.646.138.694 D08.211.589 D13.695.667.138.694 D13.695.827.068.694
|
| Concept/Terms |
NAD- NAD
- Dihydronicotinamide Adenine Dinucleotide
- Adenine Dinucleotide, Dihydronicotinamide
- Dinucleotide, Dihydronicotinamide Adenine
- Diphosphopyridine Nucleotide
- Nucleotide, Diphosphopyridine
- Nadide
- Nicotinamide-Adenine Dinucleotide
- Dinucleotide, Nicotinamide-Adenine
- Nicotinamide Adenine Dinucleotide
- Coenzyme I
- DPN
|
Below are MeSH descriptors whose meaning is more general than "NAD".
Below are MeSH descriptors whose meaning is more specific than "NAD".
This graph shows the total number of publications written about "NAD" by people in this website by year, and whether "NAD" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2002 | 0 | 4 | 4 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 5 | 6 |
| 2014 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 2 | 4 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "NAD" by people in Profiles.
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Willett E, Jiang V, Koder RL, Banta S. NAD+ Kinase Enzymes Are Reversible, and NAD+ Product Inhibition Is Responsible for the Observed Irreversibility of the Human Enzyme. Biochemistry. 2022 09 06; 61(17):1862-1873.
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Chuang TD, Quintanilla D, Boos D, Khorram O. Further characterization of tryptophan metabolism and its dysregulation in fibroids. F S Sci. 2022 11; 3(4):392-400.
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Alphonse S, Banerjee A, Dantuluri S, Shuman S, Ghose R. NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity. Nucleic Acids Res. 2021 09 27; 49(17):9607-9624.
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Shi L, Lu L, Harvey G, Harvey T, Rodr?guez-Contreras A, Alfano RR. Label-Free Fluorescence Spectroscopy for Detecting Key Biomolecules in Brain Tissue from a Mouse Model of Alzheimer's Disease. Sci Rep. 2017 06 01; 7(1):2599.
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Pitsawong W, Haynes CA, Koder RL, Rodgers DW, Miller AF. Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure. 2017 07 05; 25(7):978-987.e4.
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Hu Q, Manaenko A, Bian H, Guo Z, Huang JL, Guo ZN, Yang P, Tang J, Zhang JH. Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats. Stroke. 2017 06; 48(6):1655-1664.
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Das B, Shi L, Budansky Y, Rodriguez-Contreras A, Alfano R. Alzheimer mouse brain tissue measured by time resolved fluorescence spectroscopy using single- and multi-photon excitation of label free native molecules. J Biophotonics. 2018 01; 11(1).
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Kadam AA, Jubin T, Mir HA, Begum R. Potential role of Apoptosis Inducing Factor in evolutionarily significant eukaryote, Dictyostelium discoideum survival. Biochim Biophys Acta Gen Subj. 2017 Jan; 1861(1 Pt A):2942-2955.
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Sordillo LA, Sordillo PP, Budansky Y, Pu Y, Alfano RR. Differences in fluorescence profiles from breast cancer tissues due to changes in relative tryptophan content via energy transfer: tryptophan content correlates with histologic grade and tumor size but not with lymph node metastases. J Biomed Opt. 2014 Dec; 19(12):125002.
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Kanaan YM, Sampey BP, Beyene D, Esnakula AK, Naab TJ, Ricks-Santi LJ, Dasi S, Day A, Blackman KW, Frederick W, Copeland RL, Gabrielson E, Dewitty RL. Metabolic profile of triple-negative breast cancer in African-American women reveals potential biomarkers of aggressive disease. Cancer Genomics Proteomics. 2014 Nov-Dec; 11(6):279-94.