Heart Failure

"Heart Failure" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Descriptor ID	D006333
MeSH Number(s)	C14.280.434
Concept/Terms	Heart Failure Heart Failure Cardiac Failure Heart Decompensation Heart Decompensation Decompensation, Heart Heart Failure, Right-Sided Heart Failure, Right-Sided Heart Failure, Right Sided Right-Sided Heart Failure Right Sided Heart Failure Myocardial Failure Myocardial Failure Congestive Heart Failure Congestive Heart Failure Heart Failure, Congestive Heart Failure, Left-Sided Heart Failure, Left-Sided Heart Failure, Left Sided Left-Sided Heart Failure Left Sided Heart Failure

Below are MeSH descriptors whose meaning is more general than "Heart Failure".

Diseases [C]
Cardiovascular Diseases [C14]
Heart Diseases [C14.280]
Heart Failure [C14.280.434]

Below are MeSH descriptors whose meaning is more specific than "Heart Failure".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Heart Failure" by people in this website by year, and whether "Heart Failure" was a major or minor topic of these publications.

Bar chart showing 259 publications over 27 distinct years, with a maximum of 20 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	1	0	1
2002	5	0	5
2003	1	0	1
2004	2	1	3
2005	1	2	3
2006	3	0	3
2007	9	1	10
2008	6	1	7
2009	5	5	10
2010	7	2	9
2011	8	3	11
2012	7	0	7
2013	13	4	17
2014	5	1	6
2015	13	1	14
2016	12	4	16
2017	12	1	13
2018	19	1	20
2019	11	3	14
2020	11	3	14
2021	15	1	16
2022	14	0	14
2023	17	0	17
2024	9	1	10
2025	14	2	16
2026	1	0	1

Below are the most recent publications written about "Heart Failure" by people in Profiles.

Segan L, Kistler PM, Nanayakkara S, Taylor A, Hare J, Costello B, Chieng D, Crowley R, William J, Sugumar H, Cho K, Voskoboinik A, Ling LH, Nderitu Z, Azzopardi S, Curtin A, Premaratne M, McLellan AJ, Mariani J, Morton JB, Lee G, Joseph S, Reid C, Kaye DM, Kalman JM, Prabhu S. Withdrawal of heart failure therapy after atrial fibrillation rhythm control with ejection fraction normalization: the WITHDRAW-AF trial. Eur Heart J. 2026 Jan 07; 47(2):250-262.

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Bhatty A, Wilkinson C, Batra G, Aktaa S, Smith AB, Wahab A, Chappell S, Alfredsson J, Erlinge D, Ferreira J, Gu?mundsd?ttir IJ, Hrafnkelsd?ttir ?J, Ingimarsd?ttir IJ, Irs A, J?nosi A, J?rai Z, Oliveira-Santos M, Popescu BA, Vasko P, Vinereanu D, Yap J, Bugiardini R, Cenko E, Nadarajah R, Sydes MR, James S, Maggioni AP, Wallentin L, Casadei B, Gale CP. Standardized and hierarchically classified heart failure and complementary disease monitoring outcome measures: European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart). Eur Heart J Qual Care Clin Outcomes. 2025 Nov 04; 11(7):900-909.

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Baskaran P, Aldhaeefi M, Asaadi A, Jones M, King E, Rungkitwattanakul D, Wingate L. Empagliflozin and hydralazine-isosorbide dinitrate combination therapy improves outcomes in Black patients with heart failure. Int J Clin Pharmacol Ther. 2025 Nov; 63(11):553-556.

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Ruberg FL, Teruya S, Helmke S, Smiley DA, Fine D, Kurian D, Raiszadeh F, Prokaeva T, Spencer B, Wong S, Pandey S, Blaner WS, DeLuca A, Johnson LL, Kinkhabwala MP, Leb J, Mintz A, LaValley MP, Einstein AJ, Cohn E, Gallegos C, Murtagh G, Kelly JW, Miller EJ, Maurer MS. Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart Failure. JAMA Cardiol. 2025 Oct 01; 10(10):1034-1043.

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Goldenberg I, Zareba W, Ezekowitz JA, Albert C, Alexis JD, Anderson L, Behr ER, Daubert J, Di Palo KE, Ellenbogen KA, Dzikowicz DJ, Harrington JM, Hsich E, Huang DT, Januzzi JL, Jawaid A, Kutyifa V, Lala-Trindade A, Nakonechnyi A, Onwuanyi A, Pi?a IL, Sandhu RK, Sears S, Sroubek J, Baykaner T, Strawderman R, Beck C, Butler J. Rationale and design of the comparative effectiveness of ICD vs non-ICD therapy in contemporary heart failure patients at a low risk for arrhythmic death (CONTEMP-ICD) trial. Am Heart J. 2026 Jan; 291:162-174.

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Saha S, Ross H, Velmovitsky PE, Wang CX, Vishram-Nielsen JKK, Manlhiot C, Wang B, Cafazzo JA. Machine learning enhanced expert system for detecting heart failure decompensation using patient reported vitals and electronic health records. Sci Rep. 2025 Aug 22; 15(1):30979.

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Garrison SR, Bakal JA, Kolber MR, Korownyk CS, Green LA, Kirkwood JEM, McAlister FA, Padwal RS, Lewanczuk R, Hill MD, Singer AG, Katz A, Kelmer MD, Gayayan A, Campbell FN, Vucenovic A, Archibald NR, Yeung JMS, Youngson ERE, McGrail K, O'Neill BG, Greiver M, Manca DP, Kraut RY, Wang T, Manns BJ, Mangin DA, MacLean C, McCormack J, Wong ST, Norris C, Allan GM. Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial. JAMA. 2025 06 17; 333(23):2061-2072.

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Loayza Pintado J, Ajani T, Hernandez D, Cobos E. A Rare Culprit or an Elusive Culprit in Disguise? Unraveling Wild-Type ATTR Cardiac Amyloidosis in Heart Failure With Reduced Ejection Fraction. J Investig Med High Impact Case Rep. 2025 Jan-Dec; 13:23247096251345712.

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Wee LE, Loy EX, Lim JT, Chia YW, Lim SL, Yap J, Yeo KK, Hausenloy DJ, Chan MYY, Lye DCB, Tan KB. Omicron SARS-CoV-2 outcomes in vaccinated individuals with heart failure and ischaemic heart disease. Ann Acad Med Singap. 2025 Apr 30; 54(5):270-282.

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Rosano GMC, Teerlink JR, Kinugawa K, Bayes-Genis A, Chioncel O, Fang J, Greenberg B, Ibrahim NE, Imamura T, Inomata T, Kuwahara K, Moura B, Onwuanyi A, Sato N, Savarese G, Sakata Y, Sweitzer N, Wilcox J, Yamamoto K, Metra M, Coats AJS. The use of left ventricular ejection fraction in the diagnosis and management of heart failure. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC, the Heart Failure Society of America (HFSA), and the Japanese Heart Failure Society (JHFS). Eur J Heart Fail. 2025 Jul; 27(7):1174-1187.

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