Glioblastoma

"Glioblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Descriptor ID	D005909
MeSH Number(s)	C04.557.465.625.600.380.080.335 C04.557.470.670.380.080.335 C04.557.580.625.600.380.080.335
Concept/Terms	Glioblastoma Glioblastoma Glioblastomas Astrocytoma, Grade IV Astrocytomas, Grade IV Grade IV Astrocytoma Grade IV Astrocytomas Glioblastoma Multiforme Glioblastoma Multiforme Giant Cell Glioblastoma Giant Cell Glioblastoma Giant Cell Glioblastomas Glioblastoma, Giant Cell Glioblastomas, Giant Cell

Below are MeSH descriptors whose meaning is more general than "Glioblastoma".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neoplasms, Neuroepithelial [C04.557.465.625.600]
Glioma [C04.557.465.625.600.380]
Astrocytoma [C04.557.465.625.600.380.080]
Glioblastoma [C04.557.465.625.600.380.080.335]
Neoplasms, Glandular and Epithelial [C04.557.470]
Neoplasms, Neuroepithelial [C04.557.470.670]
Glioma [C04.557.470.670.380]
Astrocytoma [C04.557.470.670.380.080]
Glioblastoma [C04.557.470.670.380.080.335]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neoplasms, Neuroepithelial [C04.557.580.625.600]
Glioma [C04.557.580.625.600.380]
Astrocytoma [C04.557.580.625.600.380.080]
Glioblastoma [C04.557.580.625.600.380.080.335]

Below are MeSH descriptors whose meaning is related to "Glioblastoma".

Below are MeSH descriptors whose meaning is more specific than "Glioblastoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glioblastoma" by people in this website by year, and whether "Glioblastoma" was a major or minor topic of these publications.

Bar chart showing 41 publications over 19 distinct years, with a maximum of 6 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	1	2
2004	1	0	1
2005	0	1	1
2006	2	1	3
2008	2	0	2
2009	1	0	1
2010	1	0	1
2011	2	1	3
2012	1	1	2
2013	3	0	3
2014	5	0	5
2015	0	1	1
2016	1	0	1
2017	6	0	6
2019	1	0	1
2020	3	0	3
2021	1	0	1
2022	2	0	2
2023	2	0	2

Below are the most recent publications written about "Glioblastoma" by people in Profiles.

Ortiz-Rivera J, Nu?ez R, Kucheryavykh Y, Kucheryavykh L. The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model. J Neurooncol. 2023 Feb; 161(3):593-604.

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Chen X, Niu W, Fan X, Yang H, Zhao C, Fan J, Yao X, Fang Z. Oct4A palmitoylation modulates tumorigenicity and stemness in human glioblastoma cells. Neuro Oncol. 2023 01 05; 25(1):82-96.

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Valdez L, Cheng B, Gonzalez D, Rodriguez R, Campano P, Tsin A, Fang X. Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells. Oncotarget. 2022; 13:642-658.

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Manciu FS, Guerrero J, Bennet KE, Chang SY, Rahman M, Martinez Lopez LV, Chantigian S, Castellanos M, Manciu M. Assessing Nordihydroguaiaretic Acid Therapeutic Effect for Glioblastoma Multiforme. Sensors (Basel). 2022 Mar 30; 22(7).

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Awah CU, Winter J, Mazdoom CM, Ogunwobi OO. NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. Cancer Biol Ther. 2021 12 02; 22(10-12):587-597.

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Bhaskaran M, Devegowda VG, Gupta VK, Shivachar A, Bhosale RR, Arunachalam M, Vaishnavi T. Current Perspectives on Therapies, Including Drug Delivery Systems, for Managing Glioblastoma Multiforme. ACS Chem Neurosci. 2020 10 07; 11(19):2962-2977.

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Zayas-Santiago A, D?az-Garc?a A, Nu?ez-Rodr?guez R, Inyushin M. Accumulation of amyloid beta in human glioblastomas. Clin Exp Immunol. 2020 12; 202(3):325-334.

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Koga T, Chaim IA, Benitez JA, Markmiller S, Parisian AD, Hevner RF, Turner KM, Hessenauer FM, D'Antonio M, Nguyen ND, Saberi S, Ma J, Miki S, Boyer AD, Ravits J, Frazer KA, Bafna V, Chen CC, Mischel PS, Yeo GW, Furnari FB. Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nat Commun. 2020 Jan 28; 11(1):550.

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Chen X, Hao A, Li X, Ye K, Zhao C, Yang H, Ma H, Hu L, Zhao Z, Hu L, Ye F, Sun Q, Zhang H, Wang H, Yao X, Fang Z. Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression. Theranostics. 2020; 10(3):998-1015.

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Jameson NM, Ma J, Benitez J, Izurieta A, Han JY, Mendez R, Parisian A, Furnari F. Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins. Mol Cancer Res. 2019 11; 17(11):2208-2220.

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