Glioblastoma

"Glioblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Descriptor ID	D005909
MeSH Number(s)	C04.557.465.625.600.380.080.335 C04.557.470.670.380.080.335 C04.557.580.625.600.380.080.335
Concept/Terms	Glioblastoma Glioblastoma Glioblastomas Astrocytoma, Grade IV Astrocytomas, Grade IV Grade IV Astrocytoma Grade IV Astrocytomas Glioblastoma Multiforme Glioblastoma Multiforme Giant Cell Glioblastoma Giant Cell Glioblastoma Giant Cell Glioblastomas Glioblastoma, Giant Cell Glioblastomas, Giant Cell

Below are MeSH descriptors whose meaning is more general than "Glioblastoma".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neoplasms, Neuroepithelial [C04.557.465.625.600]
Glioma [C04.557.465.625.600.380]
Astrocytoma [C04.557.465.625.600.380.080]
Glioblastoma [C04.557.465.625.600.380.080.335]
Neoplasms, Glandular and Epithelial [C04.557.470]
Neoplasms, Neuroepithelial [C04.557.470.670]
Glioma [C04.557.470.670.380]
Astrocytoma [C04.557.470.670.380.080]
Glioblastoma [C04.557.470.670.380.080.335]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neoplasms, Neuroepithelial [C04.557.580.625.600]
Glioma [C04.557.580.625.600.380]
Astrocytoma [C04.557.580.625.600.380.080]
Glioblastoma [C04.557.580.625.600.380.080.335]

Below are MeSH descriptors whose meaning is related to "Glioblastoma".

Below are MeSH descriptors whose meaning is more specific than "Glioblastoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glioblastoma" by people in this website by year, and whether "Glioblastoma" was a major or minor topic of these publications.

Bar chart showing 64 publications over 22 distinct years, with a maximum of 7 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	1	2
2004	1	0	1
2005	0	1	1
2006	2	1	3
2008	2	0	2
2009	1	0	1
2010	1	0	1
2011	2	0	2
2012	1	1	2
2013	3	1	4
2014	6	0	6
2015	0	1	1
2016	2	0	2
2017	6	0	6
2019	2	0	2
2020	3	0	3
2021	3	0	3
2022	3	0	3
2023	5	0	5
2024	5	2	7
2025	4	0	4
2026	3	0	3

Below are the most recent publications written about "Glioblastoma" by people in Profiles.

Brambila C, Sahebi Vaighan N, Youssef I, Chaudhary J, Anwar A, Bachoo R, Patel T, Chopra R, Corbin IR. Enhanced delivery of low-density lipoprotein-based nanoparticles to the mouse glioblastoma using focused ultrasound as a novel therapy. Biomaterials. 2026 Oct; 333:124198.

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Del Valle MM, Colon EM, Kettimuthu K, Maner-Smith K, Olson JJ, Kucheryavykh LY. Window of opportunity study measuring defactinib and avutometinib delivery in glioblastomas. Cancer Chemother Pharmacol. 2026 Mar 06; 96(1).

View in: PubMed
Sidhu RS, Ramar V, Safir T, Jones T, Guo S, Wang G, Liu M. Rap1b promotes glioma growth and stemness via regulation of Notch1 and VEGFR2 signaling pathways. Cell Signal. 2026 Jul; 143:112457.

View in: PubMed
Xiong Z, Kong Q, Chagantipati B, Stepniak A, Jaswal AP, Sneiderman CT, Han Y, Jackson SA, Raphael RA, Zhang W, Li M, Chao Y, Qin B, Dulkadir Z, Schwegman L, Zhang Y, Kuminkoski C, Mahlke MA, Nath P, Hu B, Zinn PO, Mantica M, Agnihotri S, Nechemia-Arbely Y, Pollack IF, Rigatti LH, Forsthuber TG, Li X, Raphael I, Kohanbash G. C/EBP?-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma. Cell Mol Immunol. 2026 Jan; 23(1):94-113.

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Xiong Z, Li C, Han Q, Su Y, Cheng L, Zeng HL. Comparative quantitative proteomics of tumoral and peritumoral tissues for distinguishing human glioblastoma from low-grade astrocytoma. J Proteomics. 2026 Jan 06; 322:105547.

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Ramar V, Sidhu RS, Pako O, Cisse CR, Guo AA, Li J, Stapleton K, Guo S, Wang G, Liu M. TRIM21 functions as an oncogene in glioblastoma by transactivating FOSL1 and promoting the ubiquitination of p27. Cell Commun Signal. 2025 Jul 01; 23(1):313.

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Xiong Z, Sneiderman CT, Kuminkoski CR, Reinheimer J, Schwegman L, Sever RE, Habib A, Hu B, Agnihotri S, Rajasundaram D, Zinn PO, Forsthuber TG, Pollack IF, Li X, Raphael I, Kohanbash G. Transcript-targeted antigen mapping reveals the potential of POSTN splicing junction epitopes in glioblastoma immunotherapy. Genes Immun. 2025 06; 26(3):190-199.

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Poje G, ?akic D, Marinovic M, You J, Tarpley M, Williams KP, Golub N, Dernov?ek J, Toma?ic T, Be?ic E, Rajic Z. Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids. Acta Pharm. 2024 Dec 01; 74(4):595-612.

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Mel?ndez-V?zquez NM, Gomez-Manzano C, Godoy-Vitorino F. Oncolytic Virotherapies and Adjuvant Gut Microbiome Therapeutics to Enhance Efficacy Against Malignant Gliomas. Viruses. 2024 11 14; 16(11).

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Papacocea SI, Vrinceanu D, Dumitru M, Manole F, Serboiu C, Papacocea MT. Molecular Profile as an Outcome Predictor in Glioblastoma along with MRI Features and Surgical Resection: A Scoping Review. Int J Mol Sci. 2024 Sep 08; 25(17).

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