"Erythromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
| Descriptor ID |
D004917
|
| MeSH Number(s) |
D02.540.576.500.992
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Erythromycin".
Below are MeSH descriptors whose meaning is more specific than "Erythromycin".
This graph shows the total number of publications written about "Erythromycin" by people in this website by year, and whether "Erythromycin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 3 | 4 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Erythromycin" by people in Profiles.
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Jupelli M, Murthy AK, Chaganty BK, Guentzel MN, Selby DM, Vasquez MM, Mustafa SB, Henson BM, Seidner SR, Zhong G, Arulanandam BP. Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. Lab Invest. 2011 Oct; 91(10):1530-9.
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Yamauchi Y, Kouyama T, Itakura S, Kamiya S, Nagase T, Sunazuka T, Omura S, Takizawa H. [The effects of macrolides (EM900, clarithromycin and azithromycin) on IL-17-induced IL-8 production by airway epithelial cells]. Jpn J Antibiot. 2009 Mar; 62 Suppl A:17-21.
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Gibreel A, Wetsch NM, Taylor DE. Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni. Antimicrob Agents Chemother. 2007 Sep; 51(9):3212-6.
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Karla PK, Pal D, Quinn T, Mitra AK. Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux. Int J Pharm. 2007 May 04; 336(1):12-21.
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Karla PK, Pal D, Mitra AK. Molecular evidence and functional expression of multidrug resistance associated protein (MRP) in rabbit corneal epithelial cells. Exp Eye Res. 2007 Jan; 84(1):53-60.
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Obert CA, Miller ML, Montgomery J, Adamkiewicz T, Tuomanen EI. Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. Antimicrob Agents Chemother. 2007 Jan; 51(1):386-9.
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Kos VN, Gibreel A, Keelan M, Taylor DE. Species identification of erythromycin-resistant Campylobacter isolates and optimization of a duplex PCR for rapid detection. Res Microbiol. 2006 Jul-Aug; 157(6):503-7.
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Gibreel A, Kos VN, Keelan M, Trieber CA, Levesque S, Michaud S, Taylor DE. Macrolide resistance in Campylobacter jejuni and Campylobacter coli: molecular mechanism and stability of the resistance phenotype. Antimicrob Agents Chemother. 2005 Jul; 49(7):2753-9.
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Kumar P, Koppisch AT, Cane DE, Khosla C. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase. J Am Chem Soc. 2003 Nov 26; 125(47):14307-12.
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Kuroha M, Son DS, Shimoda M. Effects of altered plasma alpha-1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis. J Vet Pharmacol Ther. 2001 Dec; 24(6):423-31.