"Affinity Labels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
| Descriptor ID |
D000345
|
| MeSH Number(s) |
D27.720.470.410.080
|
| Concept/Terms |
Affinity Labels- Affinity Labels
- Labels, Affinity
- Affinity Labeling Reagents
- Labeling Reagents, Affinity
- Reagents, Affinity Labeling
|
Below are MeSH descriptors whose meaning is more general than "Affinity Labels".
Below are MeSH descriptors whose meaning is more specific than "Affinity Labels".
This graph shows the total number of publications written about "Affinity Labels" by people in this website by year, and whether "Affinity Labels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Affinity Labels" by people in Profiles.
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Rodina A, Taldone T, Kang Y, Patel PD, Koren J, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, Erdjument-Bromage H, Hendrickson RC, Cerchietti L, Melnick A, Guzman ML, Chiosis G. Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer. ACS Chem Biol. 2014 Aug 15; 9(8):1698-705.
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Piletz JE, Halbreich U. Imidazoline and alpha(2a)-adrenoceptor binding sites in postmenopausal women before and after estrogen replacement therapy. Biol Psychiatry. 2000 Nov 01; 48(9):932-9.
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Mocz G, Helms MK, Jameson DM, Gibbons IR. Probing the nucleotide binding sites of axonemal dynein with the fluorescent nucleotide analogue 2'(3')-O-(-N-Methylanthraniloyl)-adenosine 5'-triphosphate. Biochemistry. 1998 Jul 07; 37(27):9862-9.
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Zhu H, Halaris A, Piletz JE. Chronic imipramine treatment downregulates IR1-imidazoline receptors in rat brainstem. Life Sci. 1997; 61(19):1973-83.
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Piletz JE, Sletten K. Nonadrenergic imidazoline binding sites on human platelets. J Pharmacol Exp Ther. 1993 Dec; 267(3):1493-502.
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Mandel SJ, Berry MJ, Kieffer JD, Harney JW, Warne RL, Larsen PR. Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab. 1992 Oct; 75(4):1133-9.
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Faust FM, Slisz M, Jarrett HW. Calmodulin is labeled at lysine 148 by a chemically reactive phenothiazine. J Biol Chem. 1987 Feb 15; 262(5):1938-41.
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Jarrett HW. The synthesis and reaction of a specific affinity label for the hydrophobic drug-binding domains of calmodulin. J Biol Chem. 1984 Aug 25; 259(16):10136-44.