Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.

Neilson LM, Zhu J, Xie J, Malabarba MG, Sakamoto K, Wagner KU, Kirken RA, Rui H. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways. Mol Endocrinol. 2007 Sep; 21(9):2218-32.

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subject areas

Breast Neoplasms
Cell Line, Transformed
Cell Line, Tumor
Extracellular Signal-Regulated MAP Kinases
Female
Humans
Janus Kinase 1
Janus Kinase 2
Prolactin
Proto-Oncogene Proteins c-akt
Signal Transduction
STAT3 Transcription Factor
STAT5 Transcription Factor
Tumor Suppressor Proteins

authors with profiles

Robert Kirken

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