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Emmanuel Awumey

TitleAssociate Professor
Faculty RankAssociate Professor
InstitutionNorth Carolina Central University
DepartmentBiological and Biomedical Sciences
Address700 George Street
Durham NC 27707
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    SC1HL099139     (AWUMEY, EMMANUEL MODESTO)Sep 1, 2009 - Dec 31, 2015
    Mechanism of Desensitization of Perivascular Nerve Ca2+-sensing Receptor Signalin
    Role: Principal Investigator

    SC1HL136278     (AWUMEY, EMMANUEL MODESTO)May 1, 2017 - Feb 28, 2021
    Ca2+-Sensing Receptor Mutation and Salt-Sensitive Hypertension
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bridges LE, Williams CL, Awumey EM. High Salt Upregulates Ca2+-Sensing Receptor Expression and Ca2+-Induced Relaxation of Contracted Mesenteric Arteries from Dahl Salt-Sensitive Rats. J Pharmacol Exp Ther. 2022 05; 381(2):120-128. PMID: 35306475.
      Citations: 1     Fields:    Translation:Animals
    2. Odutola SO, Bridges LE, Awumey EM. Protein Kinase C Downregulation Enhanced Extracellular Ca2+-Induced Relaxation of Isolated Mesenteric Arteries from Aged Dahl Salt-Sensitive Rats. J Pharmacol Exp Ther. 2019 09; 370(3):427-435. PMID: 31197021.
      Citations: 5     Fields:    Translation:AnimalsCells
    3. Sesay JS, Gyapong RN, Najafi LT, Kabler SL, Diz DI, Howlett AC, Awumey EM. Gai/o-dependent Ca(2+) mobilization and Gaq-dependent PKCa regulation of Ca(2+)-sensing receptor-mediated responses in N18TG2 neuroblastoma cells. Neurochem Int. 2015 Nov; 90:142-51. PMID: 26190181.
      Citations: 2     Fields:    Translation:HumansCells
    4. Spruiell K, Jones DZ, Cullen JM, Awumey EM, Gonzalez FJ, Gyamfi MA. Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice. Biochem Pharmacol. 2014 Jun 01; 89(3):399-412. PMID: 24721462.
      Citations: 20     Fields:    Translation:HumansAnimals
    5. Spruiell K, Richardson RM, Cullen JM, Awumey EM, Gonzalez FJ, Gyamfi MA. Role of pregnane X receptor in obesity and glucose homeostasis in male mice. J Biol Chem. 2014 Feb 07; 289(6):3244-61. PMID: 24362030.
      Citations: 38     Fields:    Translation:HumansAnimals
    6. Awumey EM, Bridges LE, Williams CL, Diz DI. Nitric-oxide synthase knockout modulates Ca??-sensing receptor expression and signaling in mouse mesenteric arteries. J Pharmacol Exp Ther. 2013 Jul; 346(1):38-47. PMID: 23639802.
      Citations: 14     Fields:    Translation:AnimalsCells
    7. Bridges LE, Williams CL, Pointer MA, Awumey EM. Mesenteric artery contraction and relaxation studies using automated wire myography. J Vis Exp. 2011 Sep 22; (55). PMID: 21969063.
      Citations: 19     Fields:    Translation:Animals
    8. Chen W, Bergsman JB, Wang X, Gilkey G, Pierpoint CR, Daniel EA, Awumey EM, Dauban P, Dodd RH, Ruat M, Smith SM. Presynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals. PLoS One. 2010 Jan 05; 5(1):e8563. PMID: 20052292.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    9. Awumey EM, Hill SK, Diz DI, Bukoski RD. Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2363-70. PMID: 18375719.
      Citations: 19     Fields:    Translation:AnimalsCells
    10. Heyeraas KJ, Haug SR, Bukoski RD, Awumey EM. Identification of a Ca2+-sensing receptor in rat trigeminal ganglia, sensory axons, and tooth dental pulp. Calcif Tissue Int. 2008 Jan; 82(1):57-65. PMID: 18175029.
      Citations: 4     Fields:    Translation:AnimalsCells
    11. Awumey EM, Howlett AC, Putney JW, Diz DI, Bukoski RD. Ca(2+) mobilization through dorsal root ganglion Ca(2+)-sensing receptor stably expressed in HEK293 cells. Am J Physiol Cell Physiol. 2007 May; 292(5):C1895-905. PMID: 17267550.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    12. Awumey EM, Howlett AC, Diz DI. Is there a role for anandamide in cardiovascular regulation? Insights from studies of endocannabinoid metabolism. Am J Physiol Heart Circ Physiol. 2005 Aug; 289(2):H520-1. PMID: 16014613.
      Citations: 1     Fields:    Translation:Animals
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