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Bradley Willcox, MD MSc

Title
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentGeriatric Medicine
AddressJABSOM
Honolulu HI
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen R, Morris BJ, Donlon TA, Masaki KH, Willcox DC, Davy PMC, Allsopp RC, Willcox BJ. FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease. Aging (Albany NY). 2020 Dec 01; 12. PMID: 33260156.
      Citations:    Fields:    
    2. Nakama C, Kadowaki T, Choo J, El-Saed A, Kadota A, Willcox BJ, Fujiyoshi A, Shin C, Leader JK, Miura K, Masaki K, Ueshima H, Kuller LH, Bon J, Sekikawa A. Cross-sectional association of bone mineral density with coronary artery calcification in an international multi-ethnic population-based cohort of men aged 40-49: ERA JUMP study. Int J Cardiol Heart Vasc. 2020 Oct; 30:100618. PMID: 32904231.
      Citations:    
    3. Sorrenti V, Davinelli S, Scapagnini G, Willcox BJ, Allsopp RC, Willcox DC. Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging. Mar Drugs. 2020 Jul 05; 18(7). PMID: 32635607.
      Citations: 4     Fields:    
    4. Obhi HK, Margrett JA, Russell DW, Martin P, Poon LW, Masaki K, Willcox BJ. Factor analysis of the Cognitive Abilities Screening Instrument: Kuakini Honolulu-Asia Aging Study. Int Psychogeriatr. 2020 Jun 25; 1-9. PMID: 32583753.
      Citations:    Fields:    
    5. Mahajan H, Choo J, Masaki K, Fujiyoshi A, Guo J, Evans R, Shangguan S, Willcox B, Barinas-Mitchell E, Kadota A, Miura K, Kuller L, Shin C, Ueshima H, Sekikawa A. Serum long-chain n-3 polyunsaturated fatty acids and aortic calcification in middle-aged men: The population-based cross-sectional ERA-JUMP study. Nutr Metab Cardiovasc Dis. 2019 08; 29(8):837-846. PMID: 31151884.
      Citations:    Fields:    Translation:Humans
    6. Donlon TA, Davy PMC, Willcox BJ. Correction to: Analysis of FOXO3 Gene Polymorphisms Associated with Human Longevity. Methods Mol Biol. 2019; 1890:C1. PMID: 33296070.
      Citations:    
    7. Donlon TA, Davy PMC, Willcox BJ. Analysis of FOXO3 Gene Polymorphisms Associated with Human Longevity. Methods Mol Biol. 2019; 1890:251-258. PMID: 30414160.
      Citations:    Fields:    Translation:Humans
    8. Donlon TA, Morris BJ, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tiirikainen M, Willcox BJ. Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1459-1464. PMID: 29300832.
      Citations: 4     Fields:    Translation:Humans
    9. Davy PMC, Willcox DC, Shimabukuro M, Donlon TA, Torigoe T, Suzuki M, Higa M, Masuzaki H, Sata M, Chen R, Murkofsky RL, Morris BJ, Lim E, Allsopp RC, Willcox BJ. Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1448-1452. PMID: 29688278.
      Citations: 1     Fields:    Translation:HumansCells
    10. Morris BJ, Willcox BJ, Donlon TA. Genetic and epigenetic regulation of human aging and longevity. Biochim Biophys Acta Mol Basis Dis. 2019 07 01; 1865(7):1718-1744. PMID: 31109447.
      Citations: 1     Fields:    Translation:HumansCells
    11. Zaid M, Miura K, Okayama A, Nakagawa H, Sakata K, Saitoh S, Okuda N, Yoshita K, Choudhury SR, Rodriguez B, Masaki K, Willcox B, Miyagawa N, Okamura T, Chan Q, Elliott P, Stamler J, Ueshima H. Associations of High-Density Lipoprotein Particle and High-Density Lipoprotein Cholesterol With Alcohol Intake, Smoking, and Body Mass Index - The INTERLIPID Study. Circ J. 2018 09 25; 82(10):2557-2565. PMID: 30135319.
      Citations:    Fields:    Translation:Humans
    12. Kadowaki S, Miura K, Kadowaki T, Fujiyoshi A, El-Saed A, Masaki KH, Okamura T, Edmundowicz D, Rodriguez BL, Nakamura Y, Barinas-Mitchell EJM, Kadota A, Willcox BJ, Abbott RD, Kuller LH, Choo J, Shin C, Ueshima H, Sekikawa A. International Comparison of Abdominal Fat Distribution Among Four Populations: The ERA-JUMP Study. Metab Syndr Relat Disord. 2018 05; 16(4):166-173. PMID: 29715072.
      Citations:    Fields:    Translation:Humans
    13. Wahab N, Chen R, Curb JD, Willcox BJ, Rodriguez BL. The Association of Fasting Glucose, Insulin, and C-Peptide, with 19-Year Incidence of Coronary Heart Disease in Older Japanese-American Men; the Honolulu Heart Program. Geriatrics (Basel). 2018; 3(2). PMID: 30555835.
      Citations:    
    14. Kimata C, Willcox B, Rodriguez BL. Effects of Walking on Coronary Heart Disease in Elderly Men with Diabetes. Geriatrics (Basel). 2018 Jun; 3(2). PMID: 29904639.
      Citations:    
    15. Mahajan H, Choo J, Masaki K, Fujiyoshi A, Guo J, Hisamatsu T, Evans R, Shangguan S, Willcox B, Okamura T, Vishnu A, Barinas-Mitchell E, Ahuja V, Miura K, Kuller L, Shin C, Ueshima H, Sekikawa A. Data on alcohol consumption and coronary artery calcification among asymptomatic middle-aged men for the ERA-JUMP study. Data Brief. 2018 Apr; 17:1091-1098. PMID: 29876466.
      Citations:    
    16. Davy PMC, Allsopp RC, Donlon TA, Morris BJ, Willcox DC, Willcox BJ. FOXO3 and Exceptional Longevity: Insights From Hydra to Humans. Curr Top Dev Biol. 2018; 127:193-212. PMID: 29433738.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    17. Donlon TA, Willcox BJ, Morris BJ. FOXO3 cell resilience gene neighborhood. Aging (Albany NY). 2017 Dec 14; 9(12):2467-2468. PMID: 29242406.
      Citations: 1     Fields:    Translation:HumansAnimals
    18. Mahajan H, Choo J, Masaki K, Fujiyoshi A, Guo J, Hisamatsu T, Evans R, Shangguan S, Willcox B, Okamura T, Vishnu A, Barinas-Mitchell E, Ahuja V, Miura K, Kuller L, Shin C, Ueshima H, Sekikawa A. Association of alcohol consumption and aortic calcification in healthy men aged 40-49 years for the ERA JUMP Study. Atherosclerosis. 2018 01; 268:84-91. PMID: 29195109.
      Citations: 3     Fields:    Translation:Humans
    19. Sanada K, Chen R, Willcox B, Ohara T, Wen A, Takenaka C, Masaki K. Association of sarcopenic obesity predicted by anthropometric measurements and 24-y all-cause mortality in elderly men: The Kuakini Honolulu Heart Program. Nutrition. 2018 02; 46:97-102. PMID: 29290364.
      Citations: 5     Fields:    Translation:Humans
    20. Donlon TA, Morris BJ, He Q, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tranah GJ, Parimi N, Evans DS, Flachsbart F, Nebel A, Kim DH, Park J, Willcox BJ. Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1038-1044. PMID: 27365368.
      Citations: 4     Fields:    Translation:Humans
    21. Donlon TA, Morris BJ, Chen R, Masaki KH, Allsopp RC, Willcox DC, Elliott A, Willcox BJ. FOXO3 longevity interactome on chromosome 6. Aging Cell. 2017 10; 16(5):1016-1025. PMID: 28722347.
      Citations: 14     Fields:    Translation:HumansCells
    22. Willcox BJ, Morris BJ, Tranah GJ, Chen R, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Gerschenson M, Davy PMC, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Donlon TA. Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. J Gerontol A Biol Sci Med Sci. 2017 May 01; 72(5):724-728. PMID: 27694344.
      Citations: 8     Fields:    Translation:Humans
    23. Morris BJ, Klausner JD, Krieger JN, Willcox BJ, Crouse PD, Pollock N. Reply by Authors - Re: Canadian Pediatrics Society position statement on newborn circumcision: a risk-benefit analysis revisited. Can J Urol. 2017 Feb; 24(1):8687-8692. PMID: 28263140.
      Citations:    Fields:    Translation:Humans
    24. Guo J, Fujiyoshi A, Masaki K, Vishnu A, Kadota A, Barinas-Mitchell EJ, Hisamatsu T, Ahuja V, Takashima N, Evans RW, Willcox BJ, Miura K, Rodriguez B, Ueshima H, Kuller LH, Sekikawa A. The role of initial and longitudinal change in blood pressure on progression of arterial stiffness among multiethnic middle-aged men. J Hypertens. 2017 01; 35(1):111-117. PMID: 27775956.
      Citations: 1     Fields:    Translation:Humans
    25. Willcox BJ, Willcox DC, Suzuki M. Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Japan: Part 1-centenarians in Okinawa. Mech Ageing Dev. 2017 07; 165(Pt B):75-79. PMID: 27845177.
      Citations: 7     Fields:    Translation:Humans
    26. Guo J, Fujiyoshi A, Willcox B, Choo J, Vishnu A, Hisamatsu T, Ahuja V, Takashima N, Barinas-Mitchell E, Kadota A, Evans RW, Miura K, Edmundowicz D, Masaki K, Shin C, Kuller LH, Ueshima H, Sekikawa A. Increased Aortic Calcification Is Associated With Arterial Stiffness Progression in Multiethnic Middle-Aged Men. Hypertension. 2017 01; 69(1):102-108. PMID: 27821619.
      Citations: 9     Fields:    Translation:Humans
    27. Morris BJ, Chen R, Donlon TA, Evans DS, Tranah GJ, Parimi N, Ehret GB, Newton-Cheh C, Seto T, Willcox DC, Masaki KH, Kamide K, Ryuno H, Oguro R, Nakama C, Kabayama M, Yamamoto K, Sugimoto K, Ikebe K, Masui Y, Arai Y, Ishizaki T, Gondo Y, Rakugi H, Willcox BJ. Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension. Am J Hypertens. 2016 11 01; 29(11):1292-1300. PMID: 26476085.
      Citations: 4     Fields:    Translation:Humans
    28. Morris BJ, Klausner JD, Krieger JN, Willcox BJ, Crouse PD, Pollock N. Canadian Pediatrics Society position statement on newborn circumcision: a risk-benefit analysis revisited. Can J Urol. 2016 Oct; 23(5):8495-8502. PMID: 27705739.
      Citations: 3     Fields:    Translation:Humans
    29. Lee S, Ahuja V, Masaki K, Evans RW, Barinas-Mitchell EJ, Ueshima H, Shin C, Choo J, Hassen L, Edmundowicz D, Kuller LH, Willcox B, Sekikawa A. A Significant Positive Association of Vitamin D Deficiency with Coronary Artery Calcification among Middle-aged Men: For the ERA JUMP Study. J Am Coll Nutr. 2016 Sep-Oct; 35(7):614-620. PMID: 27315115.
      Citations: 6     Fields:    Translation:Humans
    30. Le Couteur DG, Solon-Biet S, Wahl D, Cogger VC, Willcox BJ, Willcox DC, Raubenheimer D, Simpson SJ. New Horizons: Dietary protein, ageing and the Okinawan ratio. Age Ageing. 2016 07; 45(4):443-7. PMID: 27130207.
      Citations: 10     Fields:    Translation:HumansAnimals
    31. Willcox BJ, Tranah GJ, Chen R, Morris BJ, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Davy P, Gerschenson M, Donlon TA. The FoxO3 gene and cause-specific mortality. Aging Cell. 2016 08; 15(4):617-24. PMID: 27071935.
      Citations: 20     Fields:    Translation:Humans
    32. Zeng Y, Chen H, Ni T, Ruan R, Nie C, Liu X, Feng L, Zhang F, Lu J, Li J, Li Y, Tao W, Gregory SG, Gottschalk W, Lutz MW, Land KC, Yashin A, Tan Q, Yang Z, Bolund L, Ming Q, Yang H, Min J, Willcox DC, Willcox BJ, Gu J, Hauser E, Tian XL, Vaupel JW. Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages. Rejuvenation Res. 2016 Jun; 19(3):195-203. PMID: 26414954.
      Citations:    Fields:    Translation:Humans
    33. Sekikawa A, Miyamoto Y, Miura K, Nishimura K, Willcox BJ, Masaki KH, Rodriguez B, Tracy RP, Okamura T, Kuller LH. Continuous decline in mortality from coronary heart disease in Japan despite a continuous and marked rise in total cholesterol: Japanese experience after the Seven Countries Study. Int J Epidemiol. 2015 Oct; 44(5):1614-24. PMID: 26182938.
      Citations: 7     Fields:    Translation:Humans
    34. Morris BJ, Willcox DC, Donlon TA, Willcox BJ. FOXO3: A Major Gene for Human Longevity--A Mini-Review. Gerontology. 2015; 61(6):515-25. PMID: 25832544.
      Citations: 54     Fields:    Translation:HumansAnimals
    35. Huh JY, Ross GW, Chen R, Abbott RD, Bell C, Willcox B, Launer L, Petrovitch H, Kaya B, Masaki K. Total and differential white blood cell counts in late life predict 8-year incident stroke: the Honolulu Heart Program. J Am Geriatr Soc. 2015 Mar; 63(3):439-46. PMID: 25739422.
      Citations: 2     Fields:    Translation:Humans
    36. Karino S, Willcox BJ, Fong K, Lo S, Abbott R, Masaki KH. Total and differential white blood cell counts predict eight-year incident coronary heart disease in elderly Japanese-American men: the Honolulu Heart Program. Atherosclerosis. 2015 Feb; 238(2):153-8. PMID: 25514532.
      Citations: 5     Fields:    Translation:HumansCells
    37. Morris BJ, Carnes BA, Chen R, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Allsopp R, Willcox BJ. Genetic variation in the raptor gene is associated with overweight but not hypertension in American men of Japanese ancestry. Am J Hypertens. 2015 Apr; 28(4):508-17. PMID: 25249372.
      Citations: 2     Fields:    Translation:Humans
    38. Zeng Y, Chen H, Ni T, Ruan R, Feng L, Nie C, Cheng L, Li Y, Tao W, Gu J, Land KC, Yashin A, Tan Q, Yang Z, Bolund L, Yang H, Hauser E, Willcox DC, Willcox BJ, Tian XL, Vaupel JW. GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. J Gerontol A Biol Sci Med Sci. 2015 Apr; 70(4):426-33. PMID: 24895270.
      Citations: 9     Fields:    Translation:Humans
    39. Martin P, Kelly N, Kahana B, Kahana E, Willcox BJ, Willcox DC, Poon LW. Defining successful aging: a tangible or elusive concept? Gerontologist. 2015 Feb; 55(1):14-25. PMID: 24840916.
      Citations: 40     Fields:    Translation:Humans
    40. Yahirun JJ, Hamplová D. CHILDREN'S UNION STATUS AND CONTACT WITH MOTHERS: A CROSS-NATIONAL STUDY. Demogr Res. 2014 Jan-Jun; 30:1413-1444. PMID: 19474136.
      Citations: 18     Fields:    Translation:Humans
    41. He Q, Morris BJ, Grove JS, Petrovitch H, Ross W, Masaki KH, Rodriguez B, Chen R, Donlon TA, Willcox DC, Willcox BJ. Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry. PLoS One. 2014; 9(5):e94385. PMID: 24804734.
      Citations: 21     Fields:    Translation:Humans
    42. Bell CL, Chen R, Masaki K, Yee P, He Q, Grove J, Donlon T, Curb JD, Willcox DC, Poon LW, Willcox BJ. Late-life factors associated with healthy aging in older men. J Am Geriatr Soc. 2014 May; 62(5):880-8. PMID: 24779449.
      Citations: 15     Fields:    Translation:Humans
    43. Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Allsopp R, Willcox BJ. Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. J Gerontol A Biol Sci Med Sci. 2015 Feb; 70(2):133-42. PMID: 24589862.
      Citations: 8     Fields:    Translation:Humans
    44. Willcox DC, Scapagnini G, Willcox BJ. Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet. Mech Ageing Dev. 2014 Mar-Apr; 136-137:148-62. PMID: 24462788.
      Citations: 30     Fields:    Translation:HumansAnimals
    45. Bendjilali N, Hsueh WC, He Q, Willcox DC, Nievergelt CM, Donlon TA, Kwok PY, Suzuki M, Willcox BJ. Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1474-84. PMID: 24444611.
      Citations: 3     Fields:    Translation:Humans
    46. Park Y, Wang S, Kitahara CM, Moore SC, Berrington de Gonzalez A, Bernstein L, Chang ET, Flint AJ, Freedman DM, Gaziano JM, Hoover RN, Linet MS, Purdue M, Robien K, Schairer C, Sesso HD, White E, Willcox BJ, Thun MJ, Hartge P, Willett WC. Body mass index and risk of death in Asian Americans. Am J Public Health. 2014 Mar; 104(3):520-5. PMID: 24432919.
      Citations: 16     Fields:    Translation:Humans
    47. Choo J, Shin C, Barinas-Mitchell E, Masaki K, Willcox BJ, Seto TB, Ueshima H, Lee S, Miura K, Venkitachalam L, Mackey RH, Evans RW, Kuller LH, Sutton-Tyrrell K, Sekikawa A. Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study. BMC Cardiovasc Disord. 2014 Jan 13; 14:5. PMID: 24410766.
      Citations: 20     Fields:    Translation:Humans
    48. Willcox BJ, Willcox DC. Caloric restriction, caloric restriction mimetics, and healthy aging in Okinawa: controversies and clinical implications. Curr Opin Clin Nutr Metab Care. 2014 Jan; 17(1):51-8. PMID: 24316687.
      Citations: 18     Fields:    Translation:HumansAnimals
    49. Sekikawa A, Miura K, Lee S, Fujiyoshi A, Edmundowicz D, Kadowaki T, Evans RW, Kadowaki S, Sutton-Tyrrell K, Okamura T, Bertolet M, Masaki KH, Nakamura Y, Barinas-Mitchell EJ, Willcox BJ, Kadota A, Seto TB, Maegawa H, Kuller LH, Ueshima H. Long chain n-3 polyunsaturated fatty acids and incidence rate of coronary artery calcification in Japanese men in Japan and white men in the USA: population based prospective cohort study. Heart. 2014 Apr; 100(7):569-73. PMID: 24352736.
      Citations: 19     Fields:    Translation:Humans
    50. Carnes BA, Staats D, Willcox BJ. Impact of climate change on elder health. J Gerontol A Biol Sci Med Sci. 2014 Sep; 69(9):1087-91. PMID: 24158763.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    51. Sekikawa A, Willcox BJ, Usui T, Carr JJ, Barinas-Mitchell EJ, Masaki KH, Watanabe M, Tracy RP, Bertolet MH, Evans RW, Nishimura K, Sutton-Tyrrell K, Kuller LH, Miyamoto Y. Do differences in risk factors explain the lower rates of coronary heart disease in Japanese versus U.S. women? J Womens Health (Larchmt). 2013 Nov; 22(11):966-77. PMID: 24073782.
      Citations: 1     Fields:    Translation:Humans
    52. Hirooka N, Shin C, Masaki KH, Edmundowicz D, Choo J, Barinas-Mitchell EJ, Willcox BJ, Sutton-Tyrrell K, El-Saed A, Miljkovic-Gacic I, Ohkubo T, Miura K, Ueshima H, Kuller LH, Sekikawa A. The Associations of Indices of Obesity with Lipoprotein Subfractions in Japanese American, African American and Korean Men. Glob Heart. 2013 Sep 01; 8(3):273-280. PMID: 25068101.
      Citations: 2     Fields:    
    53. Sekikawa A, Shin C, Masaki KH, Barinas-Mitchell EJ, Hirooka N, Willcox BJ, Choo J, White J, Evans RW, Fujiyoshi A, Okamura T, Miura K, Muldoon MF, Ueshima H, Kuller LH, Sutton-Tyrrell K. Association of total marine fatty acids, eicosapentaenoic and docosahexaenoic acids, with aortic stiffness in Koreans, whites, and Japanese Americans. Am J Hypertens. 2013 Nov; 26(11):1321-7. PMID: 23820020.
      Citations: 3     Fields:    Translation:Humans
    54. Morris BJ, Donlon TA, He Q, Grove JS, Masaki KH, Elliott A, Willcox DC, Willcox BJ. Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. J Gerontol A Biol Sci Med Sci. 2014 Mar; 69(3):270-3. PMID: 23770741.
      Citations: 7     Fields:    Translation:HumansCells
    55. Fujiyoshi A, Sekikawa A, Shin C, Masaki K, David Curb J, Ohkubo T, Miura K, Kadowaki T, Kadowaki S, Kadota A, Edmundowicz D, Shah A, Evans RW, Bertolet M, Choo J, Willcox BJ, Okamura T, Maegawa H, Murata K, Kuller LH, Ueshima H. A cross-sectional association of obesity with coronary calcium among Japanese, Koreans, Japanese Americans, and U.S. whites. Eur Heart J Cardiovasc Imaging. 2013 Sep; 14(9):921-7. PMID: 23764486.
      Citations: 7     Fields:    Translation:Humans
    56. Willcox B. Successful aging: is there hope? CMAJ. 2012 Dec 11; 184(18):1973-4. PMID: 23128281.
      Citations: 2     Fields:    Translation:Humans
    57. Sekikawa A, Steingrimsdottir L, Ueshima H, Shin C, Curb JD, Evans RW, Hauksdottir AM, Kadota A, Choo J, Masaki K, Thorsson B, Launer LJ, Garcia ME, Maegawa H, Willcox BJ, Eiriksdottir G, Fujiyoshi A, Miura K, Harris TB, Kuller LH, Gudnason V. Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans--a descriptive epidemiologic study. Prostaglandins Leukot Essent Fatty Acids. 2012 Jul; 87(1):11-6. PMID: 22658580.
      Citations: 12     Fields:    Translation:Humans
    58. Donlon TA, Curb JD, He Q, Grove JS, Masaki KH, Rodriguez B, Elliott A, Willcox DC, Willcox BJ. FOXO3 gene variants and human aging: coding variants may not be key players. J Gerontol A Biol Sci Med Sci. 2012 Nov; 67(11):1132-9. PMID: 22459618.
      Citations: 28     Fields:    Translation:Humans
    59. Anson RM, Willcox B, Austad S, Perls T. Within- and between-species study of extreme longevity--comments, commonalities, and goals. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):347-50. PMID: 22419221.
      Citations: 5     Fields:    Translation:HumansAnimals
    60. Ma CC, Burchfiel CM, Grove J, Fekedulegn D, Lu Y, Andrew ME, Willcox B, Masaki KH, Curb JD, Rodriguez BL. Risk factors for fractures among Japanese-American men: The Honolulu Heart Program and Honolulu-Asia Aging Study. Arch Osteoporos. 2011; 6:197-207. PMID: 22886106.
      Citations: 2     Fields:    Translation:Humans
    61. Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Willcox DC, Ohya Y, Willcox BJ, Dodge HH. Metabolic syndrome and cognitive decline among the oldest old in Okinawa: in search of a mechanism. The KOCOA Project. J Gerontol A Biol Sci Med Sci. 2012 Feb; 67(2):126-34. PMID: 22016359.
      Citations: 19     Fields:    Translation:Humans
    62. Willcox DC, Willcox BJ, Poon LW. Centenarian studies: important contributors to our understanding of the aging process and longevity. Curr Gerontol Geriatr Res. 2010; 2010:484529. PMID: 21804821.
      Citations:    
    63. Shikany JM, Flood AP, Kitahara CM, Hsing AW, Meyer TE, Willcox BJ, Redden DT, Ziegler RG. Dietary carbohydrate, glycemic index, glycemic load, and risk of prostate cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. Cancer Causes Control. 2011 Jul; 22(7):995-1002. PMID: 21553078.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    64. Rantanen T, Masaki K, He Q, Ross GW, Willcox BJ, White L. Midlife muscle strength and human longevity up to age 100 years: a 44-year prospective study among a decedent cohort. Age (Dordr). 2012 Jun; 34(3):563-70. PMID: 21541735.
      Citations: 42     Fields:    Translation:Humans
    65. Suzuki M, Willcox DC, Rosenbaum MW, Willcox BJ. Oxidative stress and longevity in okinawa: an investigation of blood lipid peroxidation and tocopherol in okinawan centenarians. Curr Gerontol Geriatr Res. 2010; 2010:380460. PMID: 21490698.
      Citations:    
    66. Genkinger JM, Spiegelman D, Anderson KE, Bernstein L, van den Brandt PA, Calle EE, English DR, Folsom AR, Freudenheim JL, Fuchs CS, Giles GG, Giovannucci E, Horn-Ross PL, Larsson SC, Leitzmann M, Männistö S, Marshall JR, Miller AB, Patel AV, Rohan TE, Stolzenberg-Solomon RZ, Verhage BA, Virtamo J, Willcox BJ, Wolk A, Ziegler RG, Smith-Warner SA. A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk. Int J Cancer. 2011 Oct 01; 129(7):1708-17. PMID: 21105029.
      Citations: 64     Fields:    Translation:Humans
    67. Ceria-Ulep CD, Grove J, Chen R, Masaki KH, Rodriguez BL, Donlon TA, Guralnik J, Willcox BJ, Willcox DC, Nigg C, Curb JD. Physical aspects of healthy aging: assessments of three measures of balance for studies in middle-aged and older adults. Curr Gerontol Geriatr Res. 2010; 2010:849761. PMID: 21437003.
      Citations:    
    68. Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, Moore SC, Tobias GS, Anton-Culver H, Freeman LB, Beeson WL, Clipp SL, English DR, Folsom AR, Freedman DM, Giles G, Hakansson N, Henderson KD, Hoffman-Bolton J, Hoppin JA, Koenig KL, Lee IM, Linet MS, Park Y, Pocobelli G, Schatzkin A, Sesso HD, Weiderpass E, Willcox BJ, Wolk A, Zeleniuch-Jacquotte A, Willett WC, Thun MJ. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010 Dec 02; 363(23):2211-9. PMID: 21121834.
      Citations: 604     Fields:    Translation:Humans
    69. Dodge HH, Katsumata Y, Todoriki H, Yasura S, Willcox DC, Bowman GL, Willcox B, Leonard S, Clemons A, Oken BS, Kaye JA, Traber MG. Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1060-7. PMID: 20643702.
      Citations: 8     Fields:    Translation:Humans
    70. He Q, Willcox BJ. Linkage disequilibrium of single-nucleotide polymorphism data: how sampling methods affect estimates of linkage disequilibrium. BMC Proc. 2009 Dec 15; 3 Suppl 7:S105. PMID: 20017969.
      Citations:    
    71. Sue LY, Schairer C, Ma X, Williams C, Chang SC, Miller AB, McCarty CA, Willcox BJ, Ziegler RG. Energy intake and risk of postmenopausal breast cancer: an expanded analysis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. Cancer Epidemiol Biomarkers Prev. 2009 Nov; 18(11):2842-50. PMID: 19843674.
      Citations: 7     Fields:    Translation:Humans
    72. Willcox DC, Willcox BJ, Todoriki H, Suzuki M. The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load. J Am Coll Nutr. 2009 Aug; 28 Suppl:500S-516S. PMID: 20234038.
      Citations: 57     Fields:    Translation:HumansAnimalsPHPublic Health
    73. Willcox BJ, Willcox DC, Ferrucci L. Secrets of healthy aging and longevity from exceptional survivors around the globe: lessons from octogenarians to supercentenarians. J Gerontol A Biol Sci Med Sci. 2008 Nov; 63(11):1181-5. PMID: 19038832.
      Citations: 23     Fields:    Translation:Humans
    74. Willcox DC, Willcox BJ, Wang NC, He Q, Rosenbaum M, Suzuki M. Life at the extreme limit: phenotypic characteristics of supercentenarians in Okinawa. J Gerontol A Biol Sci Med Sci. 2008 Nov; 63(11):1201-8. PMID: 19038835.
      Citations: 23     Fields:    Translation:Humans
    75. Koropatnick TA, Kimbell J, Chen R, Grove JS, Donlon TA, Masaki KH, Rodriguez BL, Willcox BJ, Yano K, Curb JD. A prospective study of high-density lipoprotein cholesterol, cholesteryl ester transfer protein gene variants, and healthy aging in very old Japanese-american men. J Gerontol A Biol Sci Med Sci. 2008 Nov; 63(11):1235-40. PMID: 19038839.
      Citations: 17     Fields:    Translation:Humans
    76. Willcox BJ, Donlon TA, He Q, Chen R, Grove JS, Yano K, Masaki KH, Willcox DC, Rodriguez B, Curb JD. FOXO3A genotype is strongly associated with human longevity. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13987-92. PMID: 18765803.
      Citations: 355     Fields:    Translation:Humans
    77. Sekikawa A, Curb JD, Ueshima H, El-Saed A, Kadowaki T, Abbott RD, Evans RW, Rodriguez BL, Okamura T, Sutton-Tyrrell K, Nakamura Y, Masaki K, Edmundowicz D, Kashiwagi A, Willcox BJ, Takamiya T, Mitsunami K, Seto TB, Murata K, White RL, Kuller LH. Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study. J Am Coll Cardiol. 2008 Aug 05; 52(6):417-24. PMID: 18672160.
      Citations: 77     Fields:    Translation:Humans
    78. Willcox BJ, Curb JD, Rodriguez BL. Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies. Am J Cardiol. 2008 May 22; 101(10A):75D-86D. PMID: 18474278.
      Citations: 47     Fields:    Translation:HumansCells
    79. Willcox DC, Willcox BJ, He Q, Wang NC, Suzuki M. They really are that old: a validation study of centenarian prevalence in Okinawa. J Gerontol A Biol Sci Med Sci. 2008 Apr; 63(4):338-49. PMID: 18426957.
      Citations: 18     Fields:    Translation:Humans
    80. Abbott RD, Ueshima H, Masaki KH, Willcox BJ, Rodriguez BL, Ikeda A, Yano K, White LR, Curb JD. Coronary artery calcification and total mortality in elderly men. J Am Geriatr Soc. 2007 Dec; 55(12):1948-54. PMID: 17971135.
      Citations: 9     Fields:    Translation:Humans
    81. Willcox BJ, Willcox DC, Todoriki H, Fujiyoshi A, Yano K, He Q, Curb JD, Suzuki M. Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span. Ann N Y Acad Sci. 2007 Oct; 1114:434-55. PMID: 17986602.
      Citations: 86     Fields:    Translation:HumansAnimals
    82. Abbott RD, Ueshima H, Rodriguez BL, Kadowaki T, Masaki KH, Willcox BJ, Sekikawa A, Kuller LH, Edmundowicz D, Shin C, Kashiwagi A, Nakamura Y, El-Saed A, Okamura T, White R, Curb JD. Coronary artery calcification in Japanese men in Japan and Hawaii. Am J Epidemiol. 2007 Dec 01; 166(11):1280-7. PMID: 17728270.
      Citations: 22     Fields:    Translation:Humans
    83. Willcox DC, Willcox BJ, Sokolovsky J, Sakihara S. The cultural context of "successful aging" among older women weavers in a northern Okinawan village: the role of productive activity. J Cross Cult Gerontol. 2007 Jun; 22(2):137-65. PMID: 17318443.
      Citations: 8     Fields:    Translation:Humans
    84. Willcox DC, Willcox BJ, Shimajiri S, Kurechi S, Suzuki M. Aging gracefully: a retrospective analysis of functional status in Okinawan centenarians. Am J Geriatr Psychiatry. 2007 Mar; 15(3):252-6. PMID: 17322136.
      Citations: 13     Fields:    Translation:Humans
    85. Willcox DC, Willcox BJ, Hsueh WC, Suzuki M. Genetic determinants of exceptional human longevity: insights from the Okinawa Centenarian Study. Age (Dordr). 2006 Dec; 28(4):313-32. PMID: 22253498.
      Citations: 21     Fields:    
    86. Yanagita M, Willcox BJ, Masaki KH, Chen R, He Q, Rodriguez BL, Ueshima H, Curb JD. Disability and depression: investigating a complex relation using physical performance measures. Am J Geriatr Psychiatry. 2006 Dec; 14(12):1060-8. PMID: 17138811.
      Citations: 12     Fields:    Translation:Humans
    87. Willcox BJ. Age editorial. Age (Dordr). 2006 Dec; 28(4):309-11. PMID: 22253497.
      Citations: 2     Fields:    
    88. Willcox BJ, He Q, Chen R, Yano K, Masaki KH, Grove JS, Donlon TA, Willcox DC, Curb JD. Midlife risk factors and healthy survival in men. JAMA. 2006 Nov 15; 296(19):2343-50. PMID: 17105797.
      Citations: 90     Fields:    Translation:Humans
    89. Willcox DC, Willcox BJ, Todoriki H, Curb JD, Suzuki M. Caloric restriction and human longevity: what can we learn from the Okinawans? Biogerontology. 2006 Jun; 7(3):173-7. PMID: 16810568.
      Citations: 32     Fields:    Translation:Humans
    90. Curb JD, Ceria-Ulep CD, Rodriguez BL, Grove J, Guralnik J, Willcox BJ, Donlon TA, Masaki KH, Chen R. Performance-based measures of physical function for high-function populations. J Am Geriatr Soc. 2006 May; 54(5):737-42. PMID: 16696737.
      Citations: 83     Fields:    Translation:Humans
    91. Willcox BJ, Willcox DC, He Q, Curb JD, Suzuki M. Siblings of Okinawan centenarians share lifelong mortality advantages. J Gerontol A Biol Sci Med Sci. 2006 Apr; 61(4):345-54. PMID: 16611700.
      Citations: 43     Fields:    Translation:Humans
    92. Imke C, Rodriguez BL, Grove JS, McNamara JR, Waslien C, Katz AR, Willcox B, Yano K, Curb JD. Are remnant-like particles independent predictors of coronary heart disease incidence? The Honolulu Heart study. Arterioscler Thromb Vasc Biol. 2005 Aug; 25(8):1718-22. PMID: 15947240.
      Citations: 16     Fields:    Translation:Humans
    93. Bernstein AM, Willcox BJ, Tamaki H, Kunishima N, Suzuki M, Willcox DC, Yoo JS, Perls TT. First autopsy study of an Okinawan centenarian: absence of many age-related diseases. J Gerontol A Biol Sci Med Sci. 2004 Nov; 59(11):1195-9. PMID: 15602075.
      Citations: 12     Fields:    Translation:Humans
    94. Willcox BJ, Yano K, Chen R, Willcox DC, Rodriguez BL, Masaki KH, Donlon T, Tanaka B, Curb JD. How much should we eat? The association between energy intake and mortality in a 36-year follow-up study of Japanese-American men. J Gerontol A Biol Sci Med Sci. 2004 Aug; 59(8):789-95. PMID: 15345727.
      Citations: 12     Fields:    Translation:Humans
    95. Willcox BJ, Scott JN. Growth-associated proteins and regeneration-induced gene expression in the aging neuron. Mech Ageing Dev. 2004 Jul; 125(7):513-6. PMID: 15246747.
      Citations: 2     Fields:    Translation:AnimalsCells
    96. Willcox BJ, Abbott RD, Yano K, Rodriguez BL, Willcox DC, Curb JD. C-reactive protein, cardiovascular disease and stroke: new roles for an old biomarker. Expert Rev Neurother. 2004 May; 4(3):507-18. PMID: 15853546.
      Citations: 2     Fields:    Translation:Humans
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