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Hung-Chung Huang
Title Assistant Professor in Bioinformatics and Computational Biology/Biochemistry
Faculty Rank Assistant Professor
Degree MT, MS, PhD
Institution Jackson State University
Department Biology
Clusters Cancer
Infectious and Immunological Diseases
1400 John R. Lynch St.
P.O. Box 18540
Dept. of Biology, JSU
City Jackson
State MS
Postal Code 39217
Telephone 601-790-0153
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  Research Interests:
1. Bioinformatics and Computational Biology/Biochemistry.
2. Next Generation Sequencing Data Analysis; Microarray Data Analysis.
3. Genome-wide SNP and eQTL Analyses to Identify Causative Disease-causing Genetic Allele.
4. Identification of Biomarkers for Disease Diagnosis and Prognosis.
5. Bio-molecular Molecular Dynamics Simulations and Drug Design.
6. Biological Big Data Research.

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1. Wei X, Hu H, Zheng B, Arslan Z, Huang HC, Mao W, Liu YM. Profiling metals in Cordyceps sinensis by using inductively coupled plasma mass spectrometry. Anal Methods. 2017 Jan 28; 9(4):724-728.
2. Hollman AL, Tchounwou PB, Huang HC. The Association between Gene-Environment Interactions and Diseases Involving the Human GST Superfamily with SNP Variants. Int J Environ Res Public Health. 2016 Mar 29; 13(4):379.
3. Wang GZ, Hickey SL, Shi L, Huang HC, Nakashe P, Koike N, Tu BP, Takahashi JS, Konopka G. Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale. Cell Rep. 2015 Dec 01; 13(9):1868-80.
4. Araujo DJ, Anderson AG, Berto S, Runnels W, Harper M, Ammanuel S, Rieger MA, Huang HC, Rajkovich K, Loerwald KW, Dekker JD, Tucker HO, Dougherty JD, Gibson JR, Konopka G. FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15; 29(20):2081-96.
5. Takahashi JS, Kumar V, Nakashe P, Koike N, Huang HC, Green CB, Kim TK. ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals. Methods Enzymol. 2015; 551:285-321.
6. Kumar V, Kim K, Joseph C, Kourrich S, Yoo SH, Huang HC, Vitaterna MH, de Villena FP, Churchill G, Bonci A, Takahashi JS. C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response. Science. 2013 Dec 20; 342(6165):1508-12.
7. Bridenbaugh EA, Wang W, Srimushnam M, Cromer WE, Zawieja SD, Schmidt SE, Jupiter DC, Huang HC, Van Buren V, Zawieja DC. An immunological fingerprint differentiates muscular lymphatics from arteries and veins. Lymphat Res Biol. 2013 Sep; 11(3):155-71.
8. Koike N, Yoo SH, Huang HC, Kumar V, Lee C, Kim TK, Takahashi JS. Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science. 2012 Oct 19; 338(6105):349-54.
9. Zhao Q, Huang HC, Nagaswamy U, Xia Y, Gao X, Fox GE. UNAC tetraloops: to what extent do they mimic GNRA tetraloops? Biopolymers. 2012 Aug; 97(8):617-28.
10. Huang HC, Zheng S, VanBuren V, Zhao Z. Discovering disease-specific biomarker genes for cancer diagnosis and prognosis. Technol Cancer Res Treat. 2010 Jun; 9(3):219-30.
11. Huang HC, Jupiter D, VanBuren V. Classification of genes and putative biomarker identification using distribution metrics on expression profiles. PLoS One. 2010 Feb 04; 5(2):e9056.
12. Huang HC, Jupiter D, Qiu M, Briggs JM, Vanburen V. Cluster analysis of hydration waters around the active sites of bacterial alanine racemase using a 2-ns MD simulation. Biopolymers. 2008 Mar; 89(3):210-9.
13. Li W, Liu Y, Huang HC, Peng Y, Lin Y, Ng WK, Ong KL. Dynamical systems for discovering protein complexes and functional modules from biological networks. IEEE/ACM Trans Comput Biol Bioinform. 2007 Apr-Jun; 4(2):233-50.
14. Li W, Peng Y, Huang HC, Liu Y. Biomarker discovery and visualization in gene expression data with efficient generalized matrix approximations. J Bioinform Comput Biol. 2007 Apr; 5(2a):251-79.
15. Zheng X, Huang HC, Li W, Liu P, Li QZ, Liu Y. Modeling nonlinearity in dilution design microarray data. Bioinformatics. 2007 Jun 01; 23(11):1339-47.
16. Li W, Peng Y, Huang HC, Liu Y. Efficient generalized matrix approximations for biomarker discovery and visualization in gene expression data. Comput Syst Bioinformatics Conf. 2006; 133-44.
17. Zhao Q, Nagaswamy U, Lee H, Xia Y, Huang HC, Gao X, Fox GE. NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit. Nucleic Acids Res. 2005; 33(10):3145-53.
18. Huang HC, Nagaswamy U, Fox GE. The application of cluster analysis in the intercomparison of loop structures in RNA. RNA. 2005 Apr; 11(4):412-23.
19. Huang HC, Briggs JM. The association between a negatively charged ligand and the electronegative binding pocket of its receptor. Biopolymers. 2002 Apr 05; 63(4):247-60.
20. Strych U, Huang HC, Krause KL, Benedik MJ. Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Curr Microbiol. 2000 Oct; 41(4):290-4.
21. Poovala VS, Huang H, Salahudeen AK. Role of reactive oxygen metabolites in organophosphate-bidrin-induced renal tubular cytotoxicity. J Am Soc Nephrol. 1999 Aug; 10(8):1746-52.

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