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Bellinger, Frederick P.
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overview Our research currently investigates the different roles of members of the selenoprotein family in brain function and neurological disorders. Selenoproteins are proteins that contain the strong antioxidant element selenium in the form of selenocysteine, 21st amino acid. We are examining the roles of these proteins in neuron physiology, synaptic plasticity, and in neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. Our ongoing research indicates that selenoproteins may be very important for synaptic development and function, and have found correlations of specific selenoproteins with neurodegenerative disorders.
One or more keywords matched the following items that are connected to Bellinger, Frederick P.
Item TypeName
Academic Article Role of selenoprotein P in Alzheimer's disease.
Academic Article The neuroprotective functions of selenoprotein M and its role in cytosolic calcium regulation.
Academic Article Disruption of the selenocysteine lyase-mediated selenium recycling pathway leads to metabolic syndrome in mice.
Academic Article Changes in selenoprotein P in substantia nigra and putamen in Parkinson's disease.
Academic Article Absence of selenoprotein P but not selenocysteine lyase results in severe neurological dysfunction.
Academic Article Expression and regulation of mouse selenoprotein P transcript variants differing in non-coding RNA.
Academic Article Isoform-specific binding of selenoprotein P to the ?-propeller domain of apolipoprotein E receptor 2 mediates selenium supply.
Academic Article Selenoprotein W expression and regulation in mouse brain and neurons.
Academic Article Selenium and selenoprotein function in brain disorders.
Academic Article Increased selenoprotein P in choroid plexus and cerebrospinal fluid in Alzheimer's disease brain.
Academic Article Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.
Academic Article Regulation and function of selenoproteins in human disease.
Academic Article Association of selenoprotein p with Alzheimer's pathology in human cortex.
Concept Selenoproteins
Concept Selenoprotein P
Academic Article Selenoprotein P Modulates Methamphetamine Enhancement of Vesicular Dopamine Release in Mouse Nucleus Accumbens Via Dopamine D2 Receptors.
Academic Article Selenoprotein P Regulates Synaptic Zinc and Reduces Tau Phosphorylation.
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  • Selenoproteins
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