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Harding, Wayne W.
One or more keywords matched the following items that are connected to Harding, Wayne W.
Item TypeName
Academic Article (+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners.
Academic Article Microwave-Assisted Direct Biaryl Coupling: First Application to the Synthesis of Aporphines.
Academic Article New aporphinoid 5-HT2A and a1A antagonists via structural manipulations of nantenine.
Academic Article Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine.
Academic Article Nantenine as an acetylcholinesterase inhibitor: SAR, enzyme kinetics and molecular modeling investigations.
Academic Article Affinity of aporphines for the human 5-HT2A receptor: insights from homology modeling and molecular docking studies.
Academic Article Cytotoxicity of aporphines in human colon cancer cell lines HCT-116 and Caco-2: an SAR study.
Academic Article Aporphinoid antagonists of 5-HT2A receptors: further evaluation of ring A substituents and the size of ring C.
Academic Article Evaluation of structural effects on 5-HT(2A) receptor antagonism by aporphines: identification of a new aporphine with 5-HT(2A) antagonist activity.
Academic Article Semisynthetic Studies on and Biological Evaluation of N-Methyllaurotetanine Analogues as Ligands for 5-HT Receptors.
Academic Article C4 phenyl aporphines with selective h5-HT(2B) receptor affinity.
Academic Article Synthesis and evaluation of aporphine analogs containing C1 allyl isosteres at the h5-HT(2A) receptor.
Academic Article Identification of C10 nitrogen-containing aporphines with dopamine D1 versus D5 receptor selectivity.
Academic Article Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HT7AR ligands.
Concept Aporphines
Academic Article Semisynthetic Transformations on (+)-Boldine Reveal a 5-HT2A/2CR Antagonist.
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  • Aporphines
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