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Foster, David A.

One or more keywords matched the following items that are connected to Foster, David A.

Item Type	Name
Academic Article	Targeting mTOR with rapamycin: one dose does not fit all.
Academic Article	Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells.
Academic Article	Phospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).
Academic Article	Suppression of AKT phosphorylation restores rapamycin-based synthetic lethality in SMAD4-defective pancreatic cancer cells.
Academic Article	Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle.
Academic Article	High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
Academic Article	Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-?-dependent G1 cell cycle arrest.
Academic Article	Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric.
Academic Article	Reciprocal regulation of AMP-activated protein kinase and phospholipase D.
Academic Article	Mutant ras elevates dependence on serum lipids and creates a synthetic lethality for rapamycin.
Academic Article	Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR).
Academic Article	Rapamycin-induced G1 cell cycle arrest employs both TGF-? and Rb pathways.
Academic Article	Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle.
Academic Article	5-Aminoimidazole-4-carboxamide-1-?-4-ribofuranoside (AICAR) enhances the efficacy of rapamycin in human cancer cells.
Academic Article	The Enigma of Rapamycin Dosage.
Academic Article	Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid.
Academic Article	Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine.
Academic Article	Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids.
Academic Article	Albumin promotes the progression of fibroblasts through late G1 into S-phase in the absence of growth factors.
Academic Article	Phospholipase D confers rapamycin resistance in human breast cancer cells.
Academic Article	Alternative phospholipase D/mTOR survival signal in human breast cancer cells.
Academic Article	Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
Academic Article	Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
Academic Article	[Can defective TGF-Beta signaling be an Achilles heel in human cancer?].
Concept	Sirolimus
Academic Article	Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin.
Academic Article	Regulation of mTOR by phosphatidic acid.
Academic Article	Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells.

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Sirolimus

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