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NDE, PIUS

One or more keywords matched the following properties of NDE, PIUS

Property	Value
overview	Dr. Pius N. Nde is an Associate Professor in the Department of Microbiology and Immunology at Meharry Medical College. He received his BSc and MSc degrees from the Biochemistry Department of the University of Ibadan, Nigeria and his PhD degree in Molecular Biology from Humboldt-University Berlin, Germany. Subsequently, he completed postdoctoral research training at Meharry Medical College in the laboratory of Dr. Fernando Villalta. Dr. Nde’s overall research interest focuses on “host pathogen interactions, molecular mechanisms of cardiac pathology induced by Trypanosoma cruzi and diagnosis of neglected tropical diseases.” His current SC1 research project entitled “Molecular mechanisms of Trypanosoma cruzi cardiopathogenesis ” is funded by NIAID, http://projectreporter.nih.gov/project_info_description.cfm?aid=9073494. The focus of the grant is to elucidate the molecular mechanisms utilized by T. cruzi to induce a fibrogenic response that can be exploited for the development of molecular intervention strategies. He is also a previous recipient of the SCORE SC2 grant from NIH. Currently, he is a member of ASBMB, American Society of Matrix Biology and American Heart Association. Dr. Nde’s, publications are available in the link: https://www.ncbi.nlm.nih.gov/sites/myncbi/pius.nde.1/bibliography/43068717/public/?sort=date&direction=ascending Title of Dr. Nde’s RTRN Spotlight presentation is “Molecular mechanisms of cardiac fibrosis induced by Trypanosoma cruzi infection”

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overview

Dr. Pius N. Nde is an Associate Professor in the Department of Microbiology and Immunology at Meharry Medical College. He received his BSc and MSc degrees from the Biochemistry Department of the University of Ibadan, Nigeria and his PhD degree in Molecular Biology from Humboldt-University Berlin, Germany. Subsequently, he completed postdoctoral research training at Meharry Medical College in the laboratory of Dr. Fernando Villalta. Dr. Nde’s overall research interest focuses on “host pathogen interactions, molecular mechanisms of cardiac pathology induced by Trypanosoma cruzi and diagnosis of neglected tropical diseases.” His current SC1 research project entitled “Molecular mechanisms of Trypanosoma cruzi cardiopathogenesis ” is funded by NIAID, http://projectreporter.nih.gov/project_info_description.cfm?aid=9073494. The focus of the grant is to elucidate the molecular mechanisms utilized by T. cruzi to induce a fibrogenic response that can be exploited for the development of molecular intervention strategies. He is also a previous recipient of the SCORE SC2 grant from NIH. Currently, he is a member of ASBMB, American Society of Matrix Biology and American Heart Association. Dr. Nde’s, publications are available in the link: https://www.ncbi.nlm.nih.gov/sites/myncbi/pius.nde.1/bibliography/43068717/public/?sort=date&direction=ascending Title of Dr. Nde’s RTRN Spotlight presentation is “Molecular mechanisms of cardiac fibrosis induced by Trypanosoma cruzi infection”

One or more keywords matched the following items that are connected to NDE, PIUS

Item Type	Name
Grant	Molecular mechanisms of Trypanosoma cruzi cardiopathogenesis
Grant	Novel trypanosome receptor for thrombospondin-1
Academic Article	Gene network analysis during early infection of human coronary artery smooth muscle cells by Trypanosoma cruzi and Its gp83 ligand.
Academic Article	REGULATION of the EXTRACELLULAR MATRIX INTERACTOME by Trypanosoma cruzi.
Academic Article	Regulation and use of the extracellular matrix by Trypanosoma cruzi during early infection.
Academic Article	Cellular response to Trypanosoma cruzi infection induces secretion of defensin a-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection.
Academic Article	Thrombospondin-1 interacts with Trypanosoma cruzi surface calreticulin to enhance cellular infection.
Academic Article	Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.
Academic Article	VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.
Academic Article	Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi.
Academic Article	Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase.
Academic Article	Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells.
Academic Article	Silencing of the laminin gamma-1 gene blocks Trypanosoma cruzi infection.
Academic Article	Stable RNA interference of host thrombospondin-1 blocks Trypanosoma cruzi infection.
Academic Article	Molecular cloning of a Trypanosoma cruzi cell surface casein kinase II substrate, Tc-1, involved in cellular infection.
Academic Article	Human defensin alpha-1 causes Trypanosoma cruzi membrane pore formation and induces DNA fragmentation, which leads to trypanosome destruction.
Academic Article	Molecular analysis of early host cell infection by Trypanosoma cruzi.
Concept	Trypanosoma cruzi
Concept	Variant Surface Glycoproteins, Trypanosoma
Academic Article	Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection.
Academic Article	Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells.
Academic Article	Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts.
Academic Article	Trypanosoma cruzi dysregulates expression profile of piRNAs in primary human cardiac fibroblasts during early infection phase.

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