| Item Type | Name |
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Grant
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HOST CELL INVASION BY TRYPANOSOMA CRUZI
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Grant
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Molecular Analysis of Trypanosome Infection
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Grant
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Molecular Analysis of Trypanosome Infection
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Academic Article
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Perspectives on the Trypanosoma cruzi-host cell receptor interactions.
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Academic Article
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Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
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Academic Article
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Gene network analysis during early infection of human coronary artery smooth muscle cells by Trypanosoma cruzi and Its gp83 ligand.
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Academic Article
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Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi.
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Academic Article
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REGULATION of the EXTRACELLULAR MATRIX INTERACTOME by Trypanosoma cruzi.
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Academic Article
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Targeting Trypanosoma cruzi sterol 14a-demethylase (CYP51).
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Academic Article
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Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms.
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Academic Article
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Regulation and use of the extracellular matrix by Trypanosoma cruzi during early infection.
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Academic Article
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Organocatalytic, enantioselective synthesis of VNI: a robust therapeutic development platform for Chagas, a neglected tropical disease.
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Academic Article
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Cellular response to Trypanosoma cruzi infection induces secretion of defensin a-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection.
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Academic Article
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Thrombospondin-1 interacts with Trypanosoma cruzi surface calreticulin to enhance cellular infection.
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Academic Article
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Structural basis for rational design of inhibitors targeting Trypanosoma cruzi sterol 14a-demethylase: two regions of the enzyme molecule potentiate its inhibition.
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Academic Article
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Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.
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Academic Article
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VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.
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Academic Article
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Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth.
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Academic Article
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Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
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Academic Article
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Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi.
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Academic Article
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Sterol 14a-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae.
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Academic Article
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Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase.
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Academic Article
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Successful Aspects of the Coadministration of Sterol 14a-Demethylase Inhibitor VFV and Benznidazole in Experimental Mouse Models of Chagas Disease Caused by the Drug-Resistant Strain of Trypanosoma cruzi.
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Academic Article
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Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells.
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Academic Article
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Trypanosoma cruzi uses a 45-kDa mucin for adhesion to mammalian cells.
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Academic Article
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Transforming growth factor alpha binds to Trypanosoma cruzi amastigotes to induce signaling and cellular proliferation.
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Academic Article
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Silencing of the laminin gamma-1 gene blocks Trypanosoma cruzi infection.
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Academic Article
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Human galectin-3 promotes Trypanosoma cruzi adhesion to human coronary artery smooth muscle cells.
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Academic Article
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Stable RNA interference of host thrombospondin-1 blocks Trypanosoma cruzi infection.
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Academic Article
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Molecular cloning of a Trypanosoma cruzi cell surface casein kinase II substrate, Tc-1, involved in cellular infection.
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Academic Article
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Human defensin alpha-1 causes Trypanosoma cruzi membrane pore formation and induces DNA fragmentation, which leads to trypanosome destruction.
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Academic Article
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Sterol 14alpha-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth.
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Academic Article
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Molecular analysis of early host cell infection by Trypanosoma cruzi.
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Academic Article
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CYP51: A major drug target in the cytochrome P450 superfamily.
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Academic Article
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Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase.
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Concept
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Trypanosoma
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Concept
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Trypanosoma brucei brucei
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Concept
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Trypanosoma cruzi
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Concept
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Variant Surface Glycoproteins, Trypanosoma
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Academic Article
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Novel mechanism that Trypanosoma cruzi uses to adhere to the extracellular matrix mediated by human galectin-3.
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Academic Article
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Fibronectin increases Trypanosoma cruzi amastigote binding to and uptake by murine macrophages and human monocytes.
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Academic Article
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Effects of human defensin-a(1)on Trypanosoma cruzi trypomastigotes in vitro.
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Academic Article
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Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection.
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Academic Article
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Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells.
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Academic Article
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Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts.
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