Item Type | Name |
Academic Article
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A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease.
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Academic Article
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Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
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Academic Article
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Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
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Academic Article
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Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.
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Academic Article
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Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers.
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Academic Article
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Modeling cholesterol metabolism by gene expression profiling in the hippocampus.
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Academic Article
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Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death.
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Academic Article
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Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease.
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Academic Article
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Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells.
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Academic Article
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Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.
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Academic Article
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A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.
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Academic Article
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A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes.
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Academic Article
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Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration.
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Academic Article
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Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease.
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Academic Article
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Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse.
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Academic Article
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Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.
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Academic Article
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Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein.
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Academic Article
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Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.
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Academic Article
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Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.
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Academic Article
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Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
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Academic Article
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The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.
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Academic Article
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Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.
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Academic Article
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Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.
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Academic Article
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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles.
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Academic Article
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Differences in structure and function between human and murine tau.
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Academic Article
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TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease.
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Academic Article
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High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal.
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Academic Article
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Predicting the failure of amyloid-beta vaccine.
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Academic Article
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Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis.
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Academic Article
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Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice.
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Academic Article
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Amyloid-beta: a (life) preserver for the brain.
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Academic Article
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Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
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Academic Article
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Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
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Academic Article
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Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
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Academic Article
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Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
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Academic Article
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Call for Elan to publish Alzheimer's trial details.
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Academic Article
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Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity.
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Academic Article
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Cerebral hemorrhage and amyloid-beta.
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Academic Article
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Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells.
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Academic Article
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Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants.
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Academic Article
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Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease.
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Academic Article
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Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
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Academic Article
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Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice.
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Academic Article
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Concealment of epitope by reduction and alkylation in prion protein.
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Academic Article
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Tau modifiers as therapeutic targets for Alzheimer's disease.
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Academic Article
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Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers.
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Academic Article
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Amyloid beta: the alternate hypothesis.
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Academic Article
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Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
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Academic Article
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Increases in luteinizing hormone are associated with declines in cognitive performance.
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Academic Article
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Treating the lesions, not the disease.
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Academic Article
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Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.
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Academic Article
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Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
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Academic Article
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Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease.
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Academic Article
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Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease.
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Academic Article
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Alzheimer's disease: an intracellular movement disorder?
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Academic Article
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Metal ions and oxidative protein modification in neurological disease.
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Academic Article
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Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
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Academic Article
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Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia.
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Academic Article
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Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
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Academic Article
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Nucleic acid oxidation in Alzheimer disease.
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Academic Article
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Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
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Academic Article
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Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
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Academic Article
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Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies.
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Academic Article
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Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease.
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Academic Article
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Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.
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Academic Article
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The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
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Academic Article
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Tau--an inhibitor of deacetylase HDAC6 function.
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Academic Article
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Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage.
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Academic Article
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Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity.
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Academic Article
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From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Obese
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Concept
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Mice, Transgenic
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Concept
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Mice, Knockout
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Concept
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Mice
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Academic Article
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Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system.
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Academic Article
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Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.
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Academic Article
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Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency.
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Academic Article
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Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration.
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Academic Article
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Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes.
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Academic Article
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Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease.
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Academic Article
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Paramyosin and actin in schistosomal teguments.
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Academic Article
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Hirano body filaments contain actin and actin-associated proteins.
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Academic Article
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Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions.
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Academic Article
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APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology.
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Academic Article
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Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice.
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Academic Article
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Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions.
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Academic Article
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Production of monoclonal antibodies against calmodulin by in vitro immunization of spleen cells.
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Academic Article
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Association of apolipoprotein E with murine amyloid A protein amyloid.
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Academic Article
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T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice.
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Academic Article
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Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.
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Academic Article
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Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
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Academic Article
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Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model.
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Academic Article
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Copernicus revisited: amyloid beta in Alzheimer's disease.
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Academic Article
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Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein.
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Academic Article
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Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices.
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Academic Article
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Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".
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Academic Article
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Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease.
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Academic Article
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Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function.
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Academic Article
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Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.
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Academic Article
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Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
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Academic Article
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Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology.
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Academic Article
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A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar.
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Academic Article
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Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
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Academic Article
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Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice.
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Academic Article
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Hippocampal Unicellular Recordings and Hippocampal-dependent Innate Behaviors in an Adolescent Mouse Model of Alzheimer's disease.
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Academic Article
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Mouse and Human Tau Expression in Different Brain Areas.
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Academic Article
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Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization.
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Academic Article
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Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy.
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Academic Article
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Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline.
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Academic Article
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Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice.
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