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Perry, George
One or more keywords matched the following items that are connected to Perry, George
Item TypeName
Academic Article A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease.
Academic Article Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
Academic Article Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
Academic Article Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.
Academic Article Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers.
Academic Article Modeling cholesterol metabolism by gene expression profiling in the hippocampus.
Academic Article Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death.
Academic Article Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease.
Academic Article Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells.
Academic Article Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.
Academic Article A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.
Academic Article A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes.
Academic Article Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration.
Academic Article Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease.
Academic Article Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse.
Academic Article Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.
Academic Article Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein.
Academic Article Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.
Academic Article Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.
Academic Article Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
Academic Article The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.
Academic Article Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.
Academic Article Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.
Academic Article Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles.
Academic Article Differences in structure and function between human and murine tau.
Academic Article TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease.
Academic Article High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal.
Academic Article Predicting the failure of amyloid-beta vaccine.
Academic Article Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis.
Academic Article Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice.
Academic Article Amyloid-beta: a (life) preserver for the brain.
Academic Article Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
Academic Article Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
Academic Article Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.
Academic Article Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
Academic Article Call for Elan to publish Alzheimer's trial details.
Academic Article Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity.
Academic Article Cerebral hemorrhage and amyloid-beta.
Academic Article Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells.
Academic Article Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants.
Academic Article Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease.
Academic Article Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
Academic Article Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice.
Academic Article Concealment of epitope by reduction and alkylation in prion protein.
Academic Article Tau modifiers as therapeutic targets for Alzheimer's disease.
Academic Article Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers.
Academic Article Amyloid beta: the alternate hypothesis.
Academic Article Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
Academic Article Increases in luteinizing hormone are associated with declines in cognitive performance.
Academic Article Treating the lesions, not the disease.
Academic Article Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.
Academic Article Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Academic Article Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease.
Academic Article Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease.
Academic Article Alzheimer's disease: an intracellular movement disorder?
Academic Article Metal ions and oxidative protein modification in neurological disease.
Academic Article Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
Academic Article Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia.
Academic Article Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
Academic Article Nucleic acid oxidation in Alzheimer disease.
Academic Article Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease.
Academic Article Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Academic Article Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies.
Academic Article Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease.
Academic Article Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.
Academic Article The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
Academic Article Tau--an inhibitor of deacetylase HDAC6 function.
Academic Article Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage.
Academic Article Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity.
Academic Article From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).
Concept Mice, Inbred BALB C
Concept Mice, Inbred C3H
Concept Mice, Inbred C57BL
Concept Mice, Inbred Strains
Concept Mice, Obese
Concept Mice, Transgenic
Concept Mice, Knockout
Concept Mice
Academic Article Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system.
Academic Article Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links.
Academic Article Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency.
Academic Article Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration.
Academic Article Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes.
Academic Article Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease.
Academic Article Paramyosin and actin in schistosomal teguments.
Academic Article Hirano body filaments contain actin and actin-associated proteins.
Academic Article Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions.
Academic Article APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology.
Academic Article Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice.
Academic Article Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions.
Academic Article Production of monoclonal antibodies against calmodulin by in vitro immunization of spleen cells.
Academic Article Association of apolipoprotein E with murine amyloid A protein amyloid.
Academic Article T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice.
Academic Article Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.
Academic Article Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Academic Article Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model.
Academic Article Copernicus revisited: amyloid beta in Alzheimer's disease.
Academic Article Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein.
Academic Article Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices.
Academic Article Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".
Academic Article Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease.
Academic Article Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function.
Academic Article Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.
Academic Article Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Academic Article Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology.
Academic Article A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar.
Academic Article Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Academic Article Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice.
Academic Article Hippocampal Unicellular Recordings and Hippocampal-dependent Innate Behaviors in an Adolescent Mouse Model of Alzheimer's disease.
Academic Article Mouse and Human Tau Expression in Different Brain Areas.
Academic Article Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization.
Academic Article Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy.
Academic Article Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline.
Academic Article Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice.
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