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Perry, George
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Item TypeName
Academic Article Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.
Academic Article Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons.
Academic Article NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide.
Academic Article Novel therapeutics for Alzheimer's disease: an update.
Academic Article Signaling effect of amyloid-beta(42) on the processing of AbetaPP.
Academic Article Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study.
Academic Article Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.
Academic Article Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers.
Academic Article Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid.
Academic Article Biomarkers in Alzheimer's disease: past, present and future.
Academic Article Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.
Academic Article Autophagy in Alzheimer's disease.
Academic Article Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment.
Academic Article AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation.
Academic Article Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death.
Academic Article Amyloid-? peptide structure in aqueous solution varies with fragment size.
Academic Article Do ?-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?
Academic Article Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-?(1-40) and zinc(II)-bound amyloid-?(1-42) with dynamics.
Academic Article The structures of the E22? mutant-type amyloid-? alloforms and the impact of E22? mutation on the structures of the wild-type amyloid-? alloforms.
Academic Article Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system.
Academic Article Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation.
Academic Article Intrahippocampal amyloid-? (1-40) injections injure medial septal neurons in rats.
Academic Article Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease.
Academic Article Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease.
Academic Article Accumulation of intraneuronal amyloid-? is common in normal brain.
Academic Article Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks.
Academic Article Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease.
Academic Article Elongation affinity, activation barrier, and stability of A?42 oligomers/fibrils in physiological saline.
Academic Article Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains.
Academic Article Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse.
Academic Article Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein.
Academic Article Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.
Academic Article Thermodynamics of Amyloid-? Fibril Elongation: Atomistic Details of the Transition State.
Academic Article Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.
Academic Article Precision pharmacology for Alzheimer's disease.
Academic Article Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and a-synuclein toward in vivo analysis.
Academic Article Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS.
Academic Article Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.
Academic Article The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation.
Academic Article TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease.
Academic Article Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances.
Academic Article Decreased salivary lactoferrin levels are specific to Alzheimer's disease.
Academic Article Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
Academic Article Dangers of the amyloid-beta vaccination.
Academic Article The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors.
Academic Article Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins.
Academic Article Ill-fated amyloid-beta vaccine.
Academic Article The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease.
Academic Article Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice.
Academic Article Amyloid-beta: a (life) preserver for the brain.
Academic Article Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis.
Academic Article Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease.
Academic Article Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta.
Academic Article Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply.
Academic Article Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease.
Academic Article Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
Academic Article Call for Elan to publish Alzheimer's trial details.
Academic Article Amyloid-beta: a vascular sealant that protects against hemorrhage?
Academic Article Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain.
Academic Article Iron: a pathological mediator of Alzheimer disease?
Academic Article Cerebral hemorrhage and amyloid-beta.
Academic Article Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Academic Article Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.
Academic Article Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.
Academic Article Perspectives on the amyloid-beta cascade hypothesis.
Academic Article Oxidative stress and redox-active iron in Alzheimer's disease.
Academic Article Neuroprotective properties of Bcl-w in Alzheimer disease.
Academic Article Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease.
Academic Article Mitochondrial failures in Alzheimer's disease.
Academic Article Therapeutic potential of oxidant mechanisms in Alzheimer's disease.
Academic Article Therapeutic opportunities in Alzheimer disease: one for all or all for one?
Academic Article Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?
Academic Article A second look into the oxidant mechanisms in Alzheimer's disease.
Academic Article P38 activation mediates amyloid-beta cytotoxicity.
Academic Article Amyloid beta: the alternate hypothesis.
Academic Article Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.
Academic Article Neuropathology of Alzheimer disease: pathognomonic but not pathogenic.
Academic Article Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
Academic Article Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses.
Academic Article Treating the lesions, not the disease.
Academic Article Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease.
Academic Article Staying connected: synapses in Alzheimer disease.
Academic Article Drug therapy in Alzheimer's disease.
Academic Article Redox metals and oxidative abnormalities in human prion diseases.
Academic Article Chitin-like polysaccharides in Alzheimer's disease brains.
Academic Article The fallacy of amyloid and cognition in Alzheimer's disease.
Academic Article Compensatory responses induced by oxidative stress in Alzheimer disease.
Academic Article Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.
Academic Article Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression".
Academic Article Increased expression of p130 in Alzheimer disease.
Academic Article Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
Academic Article Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide.
Academic Article Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease.
Academic Article The contribution of luteinizing hormone to Alzheimer disease pathogenesis.
Academic Article Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Academic Article Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies.
Academic Article Alzheimer disease pathology as a host response.
Academic Article Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
Academic Article Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.
Academic Article The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.
Academic Article Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches.
Academic Article Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease.
Academic Article Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Academic Article Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron.
Academic Article The role of novel chitin-like polysaccharides in Alzheimer disease.
Academic Article Current approaches in the treatment of Alzheimer's disease.
Academic Article From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).
Concept Peptides
Concept Antimicrobial Cationic Peptides
Concept Intracellular Signaling Peptides and Proteins
Academic Article ?-amyloid 1-42 induces physiological transcriptional regulation of BACE1.
Academic Article Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease.
Academic Article Microbes and Alzheimer's Disease.
Academic Article Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting A? by Using Several Synthetic and Herbal Compounds.
Academic Article Status and future directions of clinical trials in Alzheimer's disease.
Academic Article Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution.
Academic Article Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
Academic Article Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles.
Academic Article Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.
Academic Article Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease.
Academic Article Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease.
Academic Article Apolipoprotein E epsilon 4 allele frequency is not increased in progressive supranuclear palsy.
Academic Article Alzheimer's disease and prion proteins: a meeting made in muscle.
Academic Article beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease.
Academic Article Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.
Academic Article Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis.
Academic Article Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease.
Academic Article beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth.
Academic Article Neuritic plaques in Alzheimer disease originate from neurofibrillary tangles.
Academic Article Is amyloid beta-protein glycated in Alzheimer's disease?
Academic Article Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal.
Academic Article Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.
Academic Article Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Academic Article Altered glycosylation pattern of proteins in Alzheimer disease.
Academic Article Redox metals and neurodegenerative disease.
Academic Article Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model.
Academic Article Amyloid-beta junkies.
Academic Article Copernicus revisited: amyloid beta in Alzheimer's disease.
Academic Article Redox-active iron mediates amyloid-beta toxicity.
Academic Article Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices.
Academic Article Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".
Academic Article A suicide note from Alzheimer disease neurons?
Academic Article Universal isolation of cross-linked peptides: application to neurofibrillary tangles.
Academic Article Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
Academic Article Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.
Academic Article Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease.
Academic Article Oxidative stress in Alzheimer's disease.
Academic Article Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome.
Academic Article Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal.
Academic Article Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.
Academic Article Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Academic Article Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.
Academic Article Oxidative damage is the earliest event in Alzheimer disease.
Academic Article Therapeutic potential in Alzheimer disease.
Academic Article Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits.
Academic Article Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration.
Academic Article Brain and brawn: parallels in oxidative strength.
Academic Article Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology.
Academic Article Oxidative stress signaling in Alzheimer's disease.
Academic Article Ethanol-Fixed, Paraffin-Embedded Tissue Imaging: Implications for Alzheimer's Disease Research.
Academic Article A Multilevel View of the Development of Alzheimer's Disease.
Academic Article Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review.
Academic Article Lessons from antiamyloid-? immunotherapies in Alzheimer's disease.
Academic Article Conformation- and phosphorylation-dependent electron tunnelling across self-assembled monolayers of tau peptides.
Academic Article The Amyloid-? Pathway in Alzheimer's Disease.
Academic Article Playing Russian Roulette with Alzheimer's Disease Patients: Do the Cognitive Benefits of Lecanemab Outweigh the Risk of Edema, Stroke and Encephalitis?
Academic Article The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes.
Academic Article Passive Alzheimer's immunotherapy: A promising or uncertain option?
Academic Article The amyloid-? pathway in Alzheimer's disease: a plain language summary.
Academic Article MRI Monitoring of Anti-Alzheimer Therapy Amyloid-Related Imaging Abnormalities: Due Diligence or Overkill?
Academic Article Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village.
Academic Article Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects.
Academic Article Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation.
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