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One or more keywords matched the following items that are connected to Kirken, Robert
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Academic Article JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
Academic Article Selective disruption of interleukin 4 autocrine-regulated loop by a tyrosine kinase inhibitor restricts activity of T-helper 2 cells.
Academic Article Differential regulation of the Janus kinase-STAT pathway and biologic function of IL-13 in primary human NK and T cells: a comparative study with IL-4.
Academic Article Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells.
Academic Article Selective inhibition of IL-2 mRNA blocks allograft rejection by limiting T cell clonal expansion.
Academic Article PNU156804 inhibits Jak3 tyrosine kinase and rat heart allograft rejection.
Academic Article Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells.
Academic Article Allochimeric class I MHC protein-induced tolerance by partial TCR engagement requires activation of both CTL4- and common gamma-chain-dependent cytokine signals.
Academic Article New approaches to transplant immunosuppression.
Academic Article Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit.
Academic Article Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
Academic Article Regulation of T cell homeostasis by JAKs and STATs.
Academic Article The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.
Concept Lymphocyte Activation
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  • Lymphocyte Activation
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