María J. Crespo to Structure-Activity Relationship
This is a "connection" page, showing publications María J. Crespo has written about Structure-Activity Relationship.
Connection Strength
0.037
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Prat M, Fern?ndez D, Buil MA, Crespo MI, Casals G, Ferrer M, Tort L, Castro J, Monle?n JM, Gavald? A, Miralpeix M, Ramos I, Dom?nech T, Vilella D, Ant?n F, Huerta JM, Espinosa S, L?pez M, Sentellas S, Gonz?lez M, Albert? J, Segarra V, C?rdenas A, Beleta J, Ryder H. Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide). J Med Chem. 2009 Aug 27; 52(16):5076-92.
Score: 0.020
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Slee DH, Zhang X, Moorjani M, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, D?az JL, Wen J, O'Brien Z, Saunders J. Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy. J Med Chem. 2008 Feb 14; 51(3):400-6.
Score: 0.017