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Connection

Sudha Sharma to RecQ Helicases

This is a "connection" page, showing publications Sudha Sharma has written about RecQ Helicases.
Connection Strength

9.533
  1. Debnath S, Lu X, Sharma S. Transcriptional regulation by a RecQ helicase. Methods Enzymol. 2022; 673:227-249.
    View in: PubMed
    Score: 0.804
  2. Debnath S, Lu X, Lal A, Sharma S. Genome-wide investigations on regulatory functions of RECQ1 helicase. Methods. 2022 08; 204:263-268.
    View in: PubMed
    Score: 0.796
  3. Lu X, Redon CE, Tang W, Parvathaneni S, Bokhari B, Debnath S, Li XL, Muys BR, Song Y, Pongor LS, Sheikh O, Green AR, Madhusudan S, Lal A, Ambs S, Khan J, Aladjem MI, Sharma S. Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells. Mol Cell Biol. 2021 03 24; 41(4).
    View in: PubMed
    Score: 0.747
  4. Debnath S, Sharma S. RECQ1 Helicase in Genomic Stability and Cancer. Genes (Basel). 2020 06 05; 11(6).
    View in: PubMed
    Score: 0.706
  5. Parvathaneni S, Sharma S. The DNA repair helicase RECQ1 has a checkpoint-dependent role in mediating DNA damage responses induced by gemcitabine. J Biol Chem. 2019 10 18; 294(42):15330-15345.
    View in: PubMed
    Score: 0.669
  6. Sami F, Gary RK, Fang Y, Sharma S. Site-directed mutants of human RECQ1 reveal functional importance of the zinc binding domain. Mutat Res. 2016 08; 790:8-18.
    View in: PubMed
    Score: 0.533
  7. Lu X, Parvathaneni S, Li XL, Lal A, Sharma S. Transcriptome guided identification of novel functions of RECQ1 helicase. Methods. 2016 10 01; 108:111-7.
    View in: PubMed
    Score: 0.531
  8. Sami F, Lu X, Parvathaneni S, Roy R, Gary RK, Sharma S. RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin. Biochem J. 2015 Jun 01; 468(2):227-44.
    View in: PubMed
    Score: 0.499
  9. Garige M, Sharma S. Cellular deficiency of Werner syndrome protein or RECQ1 promotes genotoxic potential of hydroquinone and benzo[a]pyrene exposure. Int J Toxicol. 2014 Sep-Oct; 33(5):373-81.
    View in: PubMed
    Score: 0.475
  10. Li XL, Lu X, Parvathaneni S, Bilke S, Zhang H, Thangavel S, Vindigni A, Hara T, Zhu Y, Meltzer PS, Lal A, Sharma S. Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion. Cell Cycle. 2014; 13(15):2431-45.
    View in: PubMed
    Score: 0.453
  11. Parvathaneni S, Stortchevoi A, Sommers JA, Brosh RM, Sharma S. Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaks. PLoS One. 2013; 8(5):e62481.
    View in: PubMed
    Score: 0.432
  12. Lu X, Parvathaneni S, Hara T, Lal A, Sharma S. Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D. Mol Cancer. 2013 Apr 22; 12(1):29.
    View in: PubMed
    Score: 0.431
  13. Sharma S, Phatak P, Stortchevoi A, Jasin M, Larocque JR. RECQ1 plays a distinct role in cellular response to oxidative DNA damage. DNA Repair (Amst). 2012 Jun 01; 11(6):537-49.
    View in: PubMed
    Score: 0.403
  14. Sharma S, Brosh RM. Unique and important consequences of RECQ1 deficiency in mammalian cells. Cell Cycle. 2008 Apr 15; 7(8):989-1000.
    View in: PubMed
    Score: 0.300
  15. Sharma S, Sommers JA, Brosh RM. Processing of DNA replication and repair intermediates by the concerted action of RecQ helicases and Rad2 structure-specific nucleases. Protein Pept Lett. 2008; 15(1):89-102.
    View in: PubMed
    Score: 0.299
  16. Sharma S, Brosh RM. Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges. PLoS One. 2007 Dec 12; 2(12):e1297.
    View in: PubMed
    Score: 0.297
  17. Sharma S, Stumpo DJ, Balajee AS, Bock CB, Lansdorp PM, Brosh RM, Blackshear PJ. RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol. 2007 Mar; 27(5):1784-94.
    View in: PubMed
    Score: 0.277
  18. Woodrick J, Gupta S, Camacho S, Parvathaneni S, Choudhury S, Cheema A, Bai Y, Khatkar P, Erkizan HV, Sami F, Su Y, Sch?rer OD, Sharma S, Roy R. A new sub-pathway of long-patch base excision repair involving 5' gap formation. EMBO J. 2017 06 01; 36(11):1605-1622.
    View in: PubMed
    Score: 0.142
  19. Arora A, Parvathaneni S, Aleskandarany MA, Agarwal D, Ali R, Abdel-Fatah T, Green AR, Ball GR, Rakha EA, Ellis IO, Sharma S, Madhusudan S. Clinicopathological and Functional Significance of RECQL1 Helicase in Sporadic Breast Cancers. Mol Cancer Ther. 2017 01; 16(1):239-250.
    View in: PubMed
    Score: 0.138
  20. Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM. Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. EMBO J. 2011 Feb 16; 30(4):692-705.
    View in: PubMed
    Score: 0.092
  21. Sharma S, Doherty KM, Brosh RM. Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem J. 2006 Sep 15; 398(3):319-37.
    View in: PubMed
    Score: 0.068
  22. Sharma S, Sommers JA, Gary RK, Friedrich-Heineken E, H?bscher U, Brosh RM. The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA. Nucleic Acids Res. 2005; 33(21):6769-81.
    View in: PubMed
    Score: 0.065
  23. Sharma S, Sommers JA, Choudhary S, Faulkner JK, Cui S, Andreoli L, Muzzolini L, Vindigni A, Brosh RM. Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1. J Biol Chem. 2005 Jul 29; 280(30):28072-84.
    View in: PubMed
    Score: 0.062
  24. Sharma S, Sommers JA, Brosh RM. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication. Hum Mol Genet. 2004 Oct 01; 13(19):2247-61.
    View in: PubMed
    Score: 0.059
  25. Lashen A, Al-Kawaz A, Jeyapalan JN, Alqahtani S, Shoqafi A, Algethami M, Toss M, Green AR, Mongan NP, Sharma S, Akbari MR, Rakha EA, Madhusudan S. Immune infiltration, aggressive pathology, and poor survival outcomes in RECQL helicase deficient breast cancers. Neoplasia. 2024 01; 47:100957.
    View in: PubMed
    Score: 0.056
  26. Sharma S, Sommers JA, Wu L, Bohr VA, Hickson ID, Brosh RM. Stimulation of flap endonuclease-1 by the Bloom's syndrome protein. J Biol Chem. 2004 Mar 12; 279(11):9847-56.
    View in: PubMed
    Score: 0.056
  27. Sharma S, Otterlei M, Sommers JA, Driscoll HC, Dianov GL, Kao HI, Bambara RA, Brosh RM. WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol Biol Cell. 2004 Feb; 15(2):734-50.
    View in: PubMed
    Score: 0.056
  28. Sharma S, Sommers JA, Driscoll HC, Uzdilla L, Wilson TM, Brosh RM. The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein. J Biol Chem. 2003 Jun 27; 278(26):23487-96.
    View in: PubMed
    Score: 0.054
  29. Doherty KM, Sharma S, Uzdilla LA, Wilson TM, Cui S, Vindigni A, Brosh RM. RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination. J Biol Chem. 2005 Jul 29; 280(30):28085-94.
    View in: PubMed
    Score: 0.016
  30. Sommers JA, Sharma S, Doherty KM, Karmakar P, Yang Q, Kenny MK, Harris CC, Brosh RM. p53 modulates RPA-dependent and RPA-independent WRN helicase activity. Cancer Res. 2005 Feb 15; 65(4):1223-33.
    View in: PubMed
    Score: 0.015
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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