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Connection

Deok-Soo Son to Manganese

This is a "connection" page, showing publications Deok-Soo Son has written about Manganese.
Connection Strength

1.531
  1. Pajarillo E, Kim S, Digman A, Dutton M, Son DS, Aschner M, Lee E. The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction. J Biol Chem. 2023 07; 299(7):104879.
    View in: PubMed
    Score: 0.208
  2. Rizor A, Pajarillo E, Son DS, Aschner M, Lee E. Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes. Toxicol Lett. 2022 Feb 01; 355:41-46.
    View in: PubMed
    Score: 0.187
  3. Pajarillo E, Digman A, Nyarko-Danquah I, Son DS, Soliman KFA, Aschner M, Lee E. Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity. J Biol Chem. 2021 12; 297(6):101372.
    View in: PubMed
    Score: 0.187
  4. Rizor A, Pajarillo E, Nyarko-Danquah I, Digman A, Mooneyham L, Son DS, Aschner M, Lee E. Manganese-induced reactive oxygen species activate I?B kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro. Neurotoxicology. 2021 09; 86:94-103.
    View in: PubMed
    Score: 0.183
  5. Pajarillo E, Rizor A, Son DS, Aschner M, Lee E. The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity. J Biol Chem. 2020 03 06; 295(10):3040-3054.
    View in: PubMed
    Score: 0.165
  6. Kim J, Pajarillo E, Rizor A, Son DS, Lee J, Aschner M, Lee E. LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia. PLoS One. 2019; 14(1):e0210248.
    View in: PubMed
    Score: 0.154
  7. Johnson J, Pajarillo E, Karki P, Kim J, Son DS, Aschner M, Lee E. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. 2018 07; 67:112-120.
    View in: PubMed
    Score: 0.147
  8. Johnson J, Pajarillo EAB, Taka E, Reams R, Son DS, Aschner M, Lee E. Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. Neurotoxicology. 2018 01; 64:230-239.
    View in: PubMed
    Score: 0.138
  9. Nyarko-Danquah I, Pajarillo E, Kim S, Digman A, Multani HK, Ajayi I, Son DS, Aschner M, Lee E. Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17?-estradiol afforded protection against this manganese toxicity. Neurotoxicology. 2024 Jul; 103:105-114.
    View in: PubMed
    Score: 0.056
  10. Pajarillo E, Demayo M, Digman A, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice. Glia. 2022 10; 70(10):1886-1901.
    View in: PubMed
    Score: 0.049
  11. Karki P, Kim C, Smith K, Son DS, Aschner M, Lee E. Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-?B and Yin Yang 1 (YY1). J Biol Chem. 2015 Sep 25; 290(39):23725-37.
    View in: PubMed
    Score: 0.030
  12. Karki P, Webb A, Smith K, Johnson J, Lee K, Son DS, Aschner M, Lee E. Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. Mol Cell Biol. 2014 Apr; 34(7):1280-9.
    View in: PubMed
    Score: 0.027
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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