Fernando Villalta to Substrate Specificity
This is a "connection" page, showing publications Fernando Villalta has written about Substrate Specificity.
Connection Strength
0.205
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Augustine SA, Kleshchenko YY, Nde PN, Pratap S, Ager EA, Burns JM, Lima MF, Villalta F. Molecular cloning of a Trypanosoma cruzi cell surface casein kinase II substrate, Tc-1, involved in cellular infection. Infect Immun. 2006 Jul; 74(7):3922-9.
Score: 0.070
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Hargrove TY, Wawrzak Z, Rachakonda G, Nes WD, Villalta F, Guengerich FP, Lepesheva GI. Relaxed Substrate Requirements of Sterol 14a-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition. J Med Chem. 2021 12 09; 64(23):17511-17522.
Score: 0.051
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Lepesheva GI, Villalta F, Waterman MR. Targeting Trypanosoma cruzi sterol 14a-demethylase (CYP51). Adv Parasitol. 2011; 75:65-87.
Score: 0.024
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Lepesheva GI, Park HW, Hargrove TY, Vanhollebeke B, Wawrzak Z, Harp JM, Sundaramoorthy M, Nes WD, Pays E, Chaudhuri M, Villalta F, Waterman MR. Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections. J Biol Chem. 2010 Jan 15; 285(3):1773-80.
Score: 0.022
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Lepesheva GI, Hargrove TY, Kleshchenko Y, Nes WD, Villalta F, Waterman MR. CYP51: A major drug target in the cytochrome P450 superfamily. Lipids. 2008 Dec; 43(12):1117-25.
Score: 0.020
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Lepesheva GI, Ott RD, Hargrove TY, Kleshchenko YY, Schuster I, Nes WD, Hill GC, Villalta F, Waterman MR. Sterol 14alpha-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth. Chem Biol. 2007 Nov; 14(11):1283-93.
Score: 0.019