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Connection

George Perry to Reactive Oxygen Species

This is a "connection" page, showing publications George Perry has written about Reactive Oxygen Species.
Connection Strength

2.041
  1. Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radic Biol Med. 2006 Mar 01; 40(5):737-9.
    View in: PubMed
    Score: 0.221
  2. Casadesus G, Smith MA, Zhu X, Aliev G, Cash AD, Honda K, Petersen RB, Perry G. Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species. J Alzheimers Dis. 2004 Apr; 6(2):165-9.
    View in: PubMed
    Score: 0.195
  3. Perry G, Nunomura A, Hirai K, Zhu X, P?rez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 2002 Dec 01; 33(11):1475-9.
    View in: PubMed
    Score: 0.178
  4. Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. J Neural Transm Suppl. 2002; (62):69-75.
    View in: PubMed
    Score: 0.167
  5. Campbell A, Smith MA, Sayre LM, Bondy SC, Perry G. Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Res Bull. 2001 May 15; 55(2):125-32.
    View in: PubMed
    Score: 0.160
  6. Yeung AWK, Tzvetkov NT, Georgieva MG, Ognyanov IV, Kordos K, J?zwik A, K?hl T, Perry G, Petralia MC, Mazzon E, Atanasov AG. Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis. Antioxid Redox Signal. 2021 02 10; 34(5):402-420.
    View in: PubMed
    Score: 0.147
  7. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57.
    View in: PubMed
    Score: 0.089
  8. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40.
    View in: PubMed
    Score: 0.071
  9. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66.
    View in: PubMed
    Score: 0.069
  10. Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep; 64(17):2202-10.
    View in: PubMed
    Score: 0.062
  11. Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev Med Chem. 2007 Feb; 7(2):171-80.
    View in: PubMed
    Score: 0.059
  12. Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Curr Med Chem. 2007; 14(28):2968-75.
    View in: PubMed
    Score: 0.059
  13. Sayre LM, Moreira PI, Smith MA, Perry G. Metal ions and oxidative protein modification in neurological disease. Ann Ist Super Sanita. 2005; 41(2):143-64.
    View in: PubMed
    Score: 0.051
  14. Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN. Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev. 2003 Sep; 43(1):1-16.
    View in: PubMed
    Score: 0.047
  15. Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem. 2001 Jun; 8(7):721-38.
    View in: PubMed
    Score: 0.040
  16. Perry G, Smith MA. [Is the lesion produced by oxidation a central part in the pathogenesis of Alzheimer's disease?]. Neurologia. 1999 Feb; 14(2):78-84.
    View in: PubMed
    Score: 0.034
  17. Perry G, Smith MA. Is oxidative damage central to the pathogenesis of Alzheimer disease? Acta Neurol Belg. 1998 Jun; 98(2):175-9.
    View in: PubMed
    Score: 0.033
  18. Yan SD, Yan SF, Chen X, Fu J, Chen M, Kuppusamy P, Smith MA, Perry G, Godman GC, Nawroth P, et al. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat Med. 1995 Jul; 1(7):693-9.
    View in: PubMed
    Score: 0.027
  19. Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. ?-amyloid 1-42 induces physiological transcriptional regulation of BACE1. J Neurochem. 2012 Sep; 122(5):1023-31.
    View in: PubMed
    Score: 0.022
  20. Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors. 2012 Mar-Apr; 38(2):133-8.
    View in: PubMed
    Score: 0.021
  21. Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23.
    View in: PubMed
    Score: 0.020
  22. Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Curr Pharm Des. 2011; 17(31):3381-9.
    View in: PubMed
    Score: 0.019
  23. Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation. Neurobiol Aging. 2012 Jan; 33(1):196.e13-27.
    View in: PubMed
    Score: 0.019
  24. Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS One. 2010 Apr 21; 5(4):e10206.
    View in: PubMed
    Score: 0.019
  25. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010 Sep-Oct; 59(4-5):290-4.
    View in: PubMed
    Score: 0.019
  26. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. J Alzheimers Dis. 2010; 20 Suppl 2:S475-85.
    View in: PubMed
    Score: 0.018
  27. Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103.
    View in: PubMed
    Score: 0.018
  28. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56.
    View in: PubMed
    Score: 0.017
  29. Ramiro-Puig E, Casades?s G, Lee HG, Zhu X, McShea A, Perry G, P?rez-Cano FJ, Smith MA, Castell M. Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress. Eur J Nutr. 2009 Feb; 48(1):54-61.
    View in: PubMed
    Score: 0.017
  30. Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem. 2008 Feb; 104(3):683-95.
    View in: PubMed
    Score: 0.016
  31. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52.
    View in: PubMed
    Score: 0.015
  32. Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9.
    View in: PubMed
    Score: 0.015
  33. Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94.
    View in: PubMed
    Score: 0.014
  34. Bruckner SR, Perry G, Estus S. 4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis. J Neurochem. 2003 May; 85(4):999-1005.
    View in: PubMed
    Score: 0.011
  35. Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochem Biophys. 2003; 39(3):249-55.
    View in: PubMed
    Score: 0.011
  36. Cash AD, Perry G, Smith MA. Therapeutic potential in Alzheimer disease. Curr Med Chem. 2002 Sep; 9(17):1605-10.
    View in: PubMed
    Score: 0.011
  37. Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radic Biol Med. 2002 Jul 15; 33(2):173-81.
    View in: PubMed
    Score: 0.011
  38. Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S. Activation of NADPH oxidase in Alzheimer's disease brains. Biochem Biophys Res Commun. 2000 Jun 24; 273(1):5-9.
    View in: PubMed
    Score: 0.009
  39. Castellani RJ, Harris PL, Lecroisey A, Izadi-Pruneyre N, Wandersman C, Perry G, Smith MA. Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease. Antioxid Redox Signal. 2000; 2(1):137-42.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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