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Connection

George Perry to tau Proteins

This is a "connection" page, showing publications George Perry has written about tau Proteins.
Connection Strength

9.457
  1. Avila J, Perry G. Memory, Sleep, and Tau Function. J Alzheimers Dis. 2023; 94(2):491-495.
    View in: PubMed
    Score: 0.798
  2. Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. Int Rev Neurobiol. 2020; 154:3-50.
    View in: PubMed
    Score: 0.673
  3. Castellani RJ, Perry G. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges. J Alzheimers Dis. 2019; 67(2):447-467.
    View in: PubMed
    Score: 0.605
  4. Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2040-2047.
    View in: PubMed
    Score: 0.601
  5. Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neurodegener Dis. 2008; 5(3-4):222-4.
    View in: PubMed
    Score: 0.286
  6. Liu Q, Smith MA, Avil? J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med. 2005 Mar 15; 38(6):746-54.
    View in: PubMed
    Score: 0.232
  7. Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochim Biophys Acta. 2005 Jan 03; 1739(2-3):211-5.
    View in: PubMed
    Score: 0.229
  8. Garc?a-Carlos CA, Basurto-Islas G, Perry G, Mondrag?n-Rodr?guez S. Meta-Analysis in Transgenic Alzheimer's Disease Mouse Models Reveals Opposite Brain Network Effects of Amyloid-? and Phosphorylated Tau Proteins. J Alzheimers Dis. 2024; 99(2):595-607.
    View in: PubMed
    Score: 0.214
  9. Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Av?la J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol. 2003 May; 162(5):1623-7.
    View in: PubMed
    Score: 0.204
  10. Smith MA, Casadesus G, Joseph JA, Perry G. Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic Biol Med. 2002 Nov 01; 33(9):1194-9.
    View in: PubMed
    Score: 0.197
  11. Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochem Int. 2002 May; 40(6):527-31.
    View in: PubMed
    Score: 0.190
  12. Xolalpa-Cueva L, Garc?a-Carlos CA, Villase?or-Zepeda R, Orta-Salazar E, D?az-Cintra S, Pe?a-Ortega F, Perry G, Mondrag?n-Rodr?guez S. Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy. J Alzheimers Dis. 2022; 87(2):529-543.
    View in: PubMed
    Score: 0.186
  13. Mart?nez-Maldonado A, Ontiveros-Torres M?, Harrington CR, Montiel-Sosa JF, Prandiz RG, Bocanegra-L?pez P, Sorsby-Vargas AM, Bravo-Mu?oz M, Flor?n-Gardu?o B, Villanueva-Fierro I, Perry G, Garc?s-Ram?rez L, de la Cruz F, Mart?nez-Robles S, Pacheco-Herrero M, Luna-Mu?oz J. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration. J Alzheimers Dis. 2021; 79(4):1517-1531.
    View in: PubMed
    Score: 0.174
  14. Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293.
    View in: PubMed
    Score: 0.172
  15. Hernandes-Alejandro M, Monta?o S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, P?rez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres M?, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(2):553-569.
    View in: PubMed
    Score: 0.162
  16. Flores-Rodr?guez P, Harrington CR, Wischik CM, Ibarra-Bracamontes V, Zarco N, Navarrete A, Mart?nez-Maldonado A, Guadarrama-Ort?z P, Villanueva-Fierro I, Ontiveros-Torres MA, Perry G, Alonso AD, Floran-Gardu?o B, Segovia J, Luna-Mu?oz J. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. J Alzheimers Dis. 2019; 71(2):631-645.
    View in: PubMed
    Score: 0.151
  17. Hern?ndez F, Cuadros R, Oll? I, Garc?a C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030.
    View in: PubMed
    Score: 0.147
  18. Mondrag?n-Rodr?guez S, Salas-Gallardo A, Gonz?lez-Pereyra P, Mac?as M, Ordaz B, Pe?a-Ortega F, Aguilar-V?zquez A, Orta-Salazar E, D?az-Cintra S, Perry G, Williams S. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. J Biol Chem. 2018 06 01; 293(22):8462-8472.
    View in: PubMed
    Score: 0.144
  19. Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Mu?oz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to ? sheet in tau protein linked to Alzheimer's disease. J Enzyme Inhib Med Chem. 2017 Dec; 32(1):945-953.
    View in: PubMed
    Score: 0.140
  20. Mondrag?n-Rodr?guez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46.
    View in: PubMed
    Score: 0.132
  21. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762.
    View in: PubMed
    Score: 0.132
  22. Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016 10; 15(5):914-23.
    View in: PubMed
    Score: 0.127
  23. Ontiveros-Torres M?, Labra-Barrios ML, D?az-Cintra S, Aguilar-V?zquez AR, Moreno-Campuzano S, Flores-Rodr?guez P, Luna-Herrera C, Mena R, Perry G, Flor?n-Gardu?o B, Luna-Mu?oz J, Luna-Arias JP. Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse. J Alzheimers Dis. 2016 03 22; 52(1):243-69.
    View in: PubMed
    Score: 0.125
  24. Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016 Feb 03; 6:20352.
    View in: PubMed
    Score: 0.124
  25. Mondrag?n-Rodr?guez S, Perry G, Luna-Mu?oz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35.
    View in: PubMed
    Score: 0.108
  26. Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. J Alzheimers Dis. 2014; 40 Suppl 1:S5.
    View in: PubMed
    Score: 0.107
  27. Jarero-Basulto JJ, Luna-Mu?oz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61.
    View in: PubMed
    Score: 0.106
  28. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxid Med Cell Longev. 2013; 2013:940603.
    View in: PubMed
    Score: 0.103
  29. Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res. 2012 Nov; 43(8):694-8.
    View in: PubMed
    Score: 0.098
  30. Calder?n-Garcidue?as L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Ch?vez R, Torres-Jard?n R, Gonz?lez-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis. 2012; 28(1):93-107.
    View in: PubMed
    Score: 0.093
  31. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42.
    View in: PubMed
    Score: 0.091
  32. Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol. 2011 Jul; 70(7):578-87.
    View in: PubMed
    Score: 0.090
  33. Su B, Wang X, Lee HG, Tabaton M, Perry G, Smith MA, Zhu X. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neurosci Lett. 2010 Jan 14; 468(3):267-71.
    View in: PubMed
    Score: 0.080
  34. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66.
    View in: PubMed
    Score: 0.077
  35. Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-1406.
    View in: PubMed
    Score: 0.077
  36. Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. J Alzheimers Dis. 2008 Aug; 14(4):377-83.
    View in: PubMed
    Score: 0.073
  37. Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008 Jun 01; 105(6):2098-108.
    View in: PubMed
    Score: 0.073
  38. Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol. 2008 Jun; 67(6):523-31.
    View in: PubMed
    Score: 0.073
  39. Mondrag?n-Rodr?guez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, Garc?a-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90.
    View in: PubMed
    Score: 0.072
  40. Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75.
    View in: PubMed
    Score: 0.070
  41. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30.
    View in: PubMed
    Score: 0.062
  42. Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101.
    View in: PubMed
    Score: 0.062
  43. Santa-Mar?a I, Hern?ndez F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Mol Cell Biochem. 2005 Oct; 278(1-2):203-12.
    View in: PubMed
    Score: 0.060
  44. Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med. 2005 Apr; 11(4):164-9.
    View in: PubMed
    Score: 0.058
  45. Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Curr Neurovasc Res. 2005 Apr; 2(2):179-84.
    View in: PubMed
    Score: 0.058
  46. Avila J, P?rez M, Lucas JJ, G?mez-Ramos A, Santa Mar?a I, Moreno F, Smith M, Perry G, Hern?ndez F. Assembly in vitro of tau protein and its implications in Alzheimer's disease. Curr Alzheimer Res. 2004 May; 1(2):97-101.
    View in: PubMed
    Score: 0.055
  47. Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem. 2004 Feb; 88(3):554-63.
    View in: PubMed
    Score: 0.054
  48. G?mez-Ramos A, Smith MA, Perry G, Avila J. Tau phosphorylation and assembly. Acta Neurobiol Exp (Wars). 2004; 64(1):33-9.
    View in: PubMed
    Score: 0.053
  49. H?ilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village. Ageing Res Rev. 2024 01; 93:102173.
    View in: PubMed
    Score: 0.053
  50. Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS. Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927.
    View in: PubMed
    Score: 0.053
  51. G?mez-Ramos A, D?az-Nido J, Smith MA, Perry G, Avila J. Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. J Neurosci Res. 2003 Mar 15; 71(6):863-70.
    View in: PubMed
    Score: 0.051
  52. Hartzler AW, Zhu X, Siedlak SL, Castellani RJ, Avil? J, Perry G, Smith MA. The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau. Neurobiol Aging. 2002 Sep-Oct; 23(5):855-9.
    View in: PubMed
    Score: 0.049
  53. P?rez M, Hern?ndez F, G?mez-Ramos A, Smith M, Perry G, Avila J. Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. Eur J Biochem. 2002 Mar; 269(5):1484-9.
    View in: PubMed
    Score: 0.047
  54. Mahdiabadi S, Momtazmanesh S, Perry G, Rezaei N. Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review. Rev Neurosci. 2022 06 27; 33(4):365-381.
    View in: PubMed
    Score: 0.046
  55. Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The Amyloid-? Pathway in Alzheimer's Disease. Mol Psychiatry. 2021 10; 26(10):5481-5503.
    View in: PubMed
    Score: 0.045
  56. P?rez M, Cuadros R, Smith MA, Perry G, Avila J. Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal. FEBS Lett. 2000 Dec 15; 486(3):270-4.
    View in: PubMed
    Score: 0.043
  57. Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol. 2000 Oct; 59(10):880-8.
    View in: PubMed
    Score: 0.043
  58. Takeda A, Smith MA, Avil? J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J Neurochem. 2000 Sep; 75(3):1234-41.
    View in: PubMed
    Score: 0.042
  59. Gonz?lez-S?nchez M, Bartolome F, Antequera D, Puertas-Mart?n V, Gonz?lez P, G?mez-Grande A, Llamas-Velasco S, Herrero-San Mart?n A, P?rez-Mart?nez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Iba?ez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834.
    View in: PubMed
    Score: 0.042
  60. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30.
    View in: PubMed
    Score: 0.042
  61. Takeda A, Perry G, Abraham NG, Dwyer BE, Kutty RK, Laitinen JT, Petersen RB, Smith MA. Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem. 2000 Feb 25; 275(8):5395-9.
    View in: PubMed
    Score: 0.041
  62. Reyes-Pablo AE, Campa-C?rdoba BB, Luna-Viramontes NI, Ontiveros-Torres M?, Villanueva-Fierro I, Bravo-Mu?oz M, S?enz-Ibarra B, Barbosa O, Guadarrama-Ort?z P, Garc?s-Ram?rez L, de la Cruz F, Harrington CR, Mart?nez-Robles S, Gonz?lez-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in M?xico. J Alzheimers Dis. 2020; 76(3):853-862.
    View in: PubMed
    Score: 0.041
  63. Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 Aug 02; 10(11):2411-5.
    View in: PubMed
    Score: 0.039
  64. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289.
    View in: PubMed
    Score: 0.038
  65. Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087.
    View in: PubMed
    Score: 0.038
  66. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 04; 130:331-365.
    View in: PubMed
    Score: 0.036
  67. Giaccone G, Pedrotti B, Migheli A, Verga L, Perez J, Racagni G, Smith MA, Perry G, De Gioia L, Selvaggini C, Salmona M, Ghiso J, Frangione B, Islam K, Bugiani O, Tagliavini F. beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. Am J Pathol. 1996 Jan; 148(1):79-87.
    View in: PubMed
    Score: 0.031
  68. Yan SD, Yan SF, Chen X, Fu J, Chen M, Kuppusamy P, Smith MA, Perry G, Godman GC, Nawroth P, et al. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat Med. 1995 Jul; 1(7):693-9.
    View in: PubMed
    Score: 0.030
  69. Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol. 2015 Jun; 74(6):493-9.
    View in: PubMed
    Score: 0.029
  70. Smith MA, Sayre LM, Vitek MP, Monnier VM, Perry G. Early AGEing and Alzheimer's. Nature. 1995 Mar 23; 374(6520):316.
    View in: PubMed
    Score: 0.029
  71. Richey PL, Siedlak SL, Smith MA, Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):657-63.
    View in: PubMed
    Score: 0.029
  72. Kawai M, Cras P, Richey P, Tabaton M, Lowery DE, Gonzalez-DeWhitt PA, Greenberg BD, Gambetti P, Perry G. Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease. Am J Pathol. 1992 Apr; 140(4):947-58.
    View in: PubMed
    Score: 0.024
  73. Vande Weghe J, Cras P, Kawai M, Siedlak SL, Tabaton M, Greenberg B, Perry G. Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease. Brain Res. 1991 Sep 27; 560(1-2):303-5.
    View in: PubMed
    Score: 0.023
  74. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7552-6.
    View in: PubMed
    Score: 0.023
  75. Perry G, Kawai M, Tabaton M, Onorato M, Mulvihill P, Richey P, Morandi A, Connolly JA, Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J Neurosci. 1991 Jun; 11(6):1748-55.
    View in: PubMed
    Score: 0.022
  76. Mondrag?n-Rodr?guez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev Neurother. 2010 May; 10(5):683-91.
    View in: PubMed
    Score: 0.021
  77. Bonda DJ, Lee HP, Lee HG, Friedlich AL, Perry G, Zhu X, Smith MA. Novel therapeutics for Alzheimer's disease: an update. Curr Opin Drug Discov Devel. 2010 Mar; 13(2):235-46.
    View in: PubMed
    Score: 0.020
  78. Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomark Med. 2010 Feb; 4(1):15-26.
    View in: PubMed
    Score: 0.020
  79. Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96.
    View in: PubMed
    Score: 0.020
  80. Galloway PG, Bergeron C, Perry G. The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease. Neurosci Lett. 1989 May 22; 100(1-3):6-10.
    View in: PubMed
    Score: 0.019
  81. Mulvihill P, Perry G. Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau. Brain Res. 1989 Apr 10; 484(1-2):150-6.
    View in: PubMed
    Score: 0.019
  82. Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int. 2009 Feb; 54(2):84-8.
    View in: PubMed
    Score: 0.019
  83. Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis. 2008 Dec; 15(4):615-24.
    View in: PubMed
    Score: 0.019
  84. Lee HG, Zhu X, Casadesus G, Pall?s M, Camins A, O'Neill MJ, Nakanishi S, Perry G, Smith MA. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res. 2009 Jan 16; 1249:244-50.
    View in: PubMed
    Score: 0.019
  85. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9.
    View in: PubMed
    Score: 0.017
  86. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother. 2007 May; 7(5):473-85.
    View in: PubMed
    Score: 0.017
  87. Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61.
    View in: PubMed
    Score: 0.016
  88. Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007 Apr; 1772(4):494-502.
    View in: PubMed
    Score: 0.016
  89. Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10.
    View in: PubMed
    Score: 0.016
  90. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9.
    View in: PubMed
    Score: 0.016
  91. Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25.
    View in: PubMed
    Score: 0.015
  92. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23.
    View in: PubMed
    Score: 0.015
  93. Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxid Redox Signal. 2004 Oct; 6(5):888-94.
    View in: PubMed
    Score: 0.014
  94. Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathol. 2004 Apr; 107(4):365-71.
    View in: PubMed
    Score: 0.013
  95. Ogawa O, Lee HG, Zhu X, Raina A, Harris PL, Castellani RJ, Perry G, Smith MA. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2003 04; 2(2):105-10.
    View in: PubMed
    Score: 0.013
  96. Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology. 2002 Feb 26; 58(4):589-92.
    View in: PubMed
    Score: 0.012
  97. Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem. 2001 Jan; 76(2):435-41.
    View in: PubMed
    Score: 0.011
  98. Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, Menini S, Traverso N, Zaccheo D, Siedlak S, Perry G, Smith MA, Tabaton M. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol. 2000 May; 59(5):393-7.
    View in: PubMed
    Score: 0.010
  99. Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem. 2000 Jan; 74(1):270-9.
    View in: PubMed
    Score: 0.010
  100. Guevara J, Espinosa B, Zenteno E, V?zguez L, Luna J, Perry G, Mena R. Altered glycosylation pattern of proteins in Alzheimer disease. J Neuropathol Exp Neurol. 1998 Oct; 57(10):905-14.
    View in: PubMed
    Score: 0.009
  101. Shimohama S, Perry G, Richey P, Praprotnik D, Takenawa T, Fukami K, Whitehouse PJ, Kimura J. Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles. Brain Res. 1995 Jan 16; 669(2):217-24.
    View in: PubMed
    Score: 0.007
  102. Tabaton M, Cammarata S, Mancardi G, Manetto V, Autilio-Gambetti L, Perry G, Gambetti P. Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2098-102.
    View in: PubMed
    Score: 0.006
  103. Tabaton M, Cammarata S, Mancardi GL, Cordone G, Perry G, Loeb C. Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease. Neurology. 1991 Mar; 41(3):391-4.
    View in: PubMed
    Score: 0.005
  104. Tabaton M, Mandybur TI, Perry G, Onorato M, Autilio-Gambetti L, Gambetti P. The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition. Ann Neurol. 1989 Dec; 26(6):771-8.
    View in: PubMed
    Score: 0.005
  105. Tabaton M, Cammarata S, Manetto V, Perry G, Mancardi G. Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease. Neurosci Lett. 1989 Sep 11; 103(3):259-62.
    View in: PubMed
    Score: 0.005
  106. Galloway PG, Perry G, Kosik KS, Gambetti P. Hirano bodies contain tau protein. Brain Res. 1987 Feb 17; 403(2):337-40.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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