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Connection

George Perry to Alzheimer Disease

This is a "connection" page, showing publications George Perry has written about Alzheimer Disease.
Connection Strength

48.540
  1. Plascencia-Villa G, Castellani RJ, Perry G. Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease. Proc Natl Acad Sci U S A. 2024 Aug 06; 121(32):e2412255121.
    View in: PubMed
    Score: 0.579
  2. Liang J, LaFleur B, Hussainy S, Perry G. Gene Co-Expression Analysis of Multiple Brain Tissues Reveals Correlation of FAM222A Expression with Multiple Alzheimer's Disease-Related Genes. J Alzheimers Dis. 2024; 99(s2):S249-S263.
    View in: PubMed
    Score: 0.556
  3. Perry G. Alzheimer's Disease: Not Just for the Aged? J Alzheimers Dis. 2023; 91(3):923-924.
    View in: PubMed
    Score: 0.519
  4. Plascencia-Villa G, Perry G. Lessons from antiamyloid-? immunotherapies in Alzheimer's disease. Handb Clin Neurol. 2023; 193:267-292.
    View in: PubMed
    Score: 0.519
  5. Atwood CS, Perry G. Playing Russian Roulette with Alzheimer's Disease Patients: Do the Cognitive Benefits of Lecanemab Outweigh the Risk of Edema, Stroke and Encephalitis? J Alzheimers Dis. 2023; 92(3):799-801.
    View in: PubMed
    Score: 0.519
  6. Plascencia-Villa G, Perry G. Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia. Am J Pathol. 2022 10; 192(10):1340-1346.
    View in: PubMed
    Score: 0.504
  7. Mandal PK, Perry G. SWADESH: A Comprehensive Platform for Multimodal Data and Analytics for Advanced Research in Alzheimer's Disease and Other Brain Disorders. J Alzheimers Dis. 2022; 85(1):1-5.
    View in: PubMed
    Score: 0.484
  8. Ashford JW, Schmitt FA, Bergeron MF, Bayley PJ, Clifford JO, Xu Q, Liu X, Zhou X, Kumar V, Buschke H, Dean M, Finkel SI, Hyer L, Perry G. Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement. J Alzheimers Dis. 2022; 87(1):305-315.
    View in: PubMed
    Score: 0.484
  9. Nunomura A, Perry G. RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs. Oxid Med Cell Longev. 2020; 2020:2638130.
    View in: PubMed
    Score: 0.449
  10. Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293.
    View in: PubMed
    Score: 0.449
  11. Kelley AR, Colley M, Dyer S, Bach SBH, Zhu X, Perry G. Ethanol-Fixed, Paraffin-Embedded Tissue Imaging: Implications for Alzheimer's Disease Research. J Am Soc Mass Spectrom. 2020 Dec 02; 31(12):2416-2420.
    View in: PubMed
    Score: 0.440
  12. Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. Int Rev Neurobiol. 2020; 154:3-50.
    View in: PubMed
    Score: 0.438
  13. Plascencia-Villa G, Perry G. Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis. Antioxid Redox Signal. 2021 03 10; 34(8):591-610.
    View in: PubMed
    Score: 0.438
  14. Perry G. Alzheimer's Disease Patients in the Crosshairs of COVID-19. J Alzheimers Dis. 2020; 76(1):1.
    View in: PubMed
    Score: 0.422
  15. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders. Neurotherapeutics. 2019 07; 16(3):666-674.
    View in: PubMed
    Score: 0.407
  16. Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Lab Invest. 2019 07; 99(7):958-970.
    View in: PubMed
    Score: 0.397
  17. Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2040-2047.
    View in: PubMed
    Score: 0.390
  18. Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4).
    View in: PubMed
    Score: 0.373
  19. Plascencia-Villa G, Perry G. Iron?ic facts about dementia. J Neurol Neurosurg Psychiatry. 2018 05; 89(5):446-447.
    View in: PubMed
    Score: 0.368
  20. Reale M, D'Angelo C, Costantini E, Di Nicola M, Yarla NS, Kamal MA, Salvador N, Perry G. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology. J Alzheimers Dis. 2018; 62(1):467-476.
    View in: PubMed
    Score: 0.367
  21. Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. J Alzheimers Dis. 2018; 64(s1):S1.
    View in: PubMed
    Score: 0.367
  22. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Thermodynamics of Amyloid-? Fibril Elongation: Atomistic Details of the Transition State. ACS Chem Neurosci. 2018 04 18; 9(4):783-789.
    View in: PubMed
    Score: 0.367
  23. Hajipour MJ, Santoso MR, Rezaee F, Aghaverdi H, Mahmoudi M, Perry G. Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology. Trends Biotechnol. 2017 10; 35(10):937-953.
    View in: PubMed
    Score: 0.354
  24. Nunomura A, Zhu X, Perry G. Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration. J Alzheimers Dis. 2017; 55(1):73-75.
    View in: PubMed
    Score: 0.342
  25. Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9.
    View in: PubMed
    Score: 0.329
  26. Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jim?nez MJ, Zhu X, Rogers JT, Betancourt I, Jos?-Yacam?n M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep. 2016 04 28; 6:24873.
    View in: PubMed
    Score: 0.327
  27. Forero DA, Gonz?lez-Giraldo Y, L?pez-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2016 08; 71(8):1069-73.
    View in: PubMed
    Score: 0.326
  28. Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting A? by Using Several Synthetic and Herbal Compounds. Oxid Med Cell Longev. 2016; 2016:7361613.
    View in: PubMed
    Score: 0.319
  29. Calder?n-Garcidue?as L, Franco-Lira M, D'Angiulli A, Rodr?guez-D?az J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jard?n R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ Res. 2015 Jul; 140:579-92.
    View in: PubMed
    Score: 0.307
  30. Perry G. Two hundred treasured issues! J Alzheimers Dis. 2015; 44(3):725.
    View in: PubMed
    Score: 0.298
  31. Rodrigues R, Petersen RB, Perry G. Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability. Cell Mol Neurobiol. 2014 Oct; 34(7):925-49.
    View in: PubMed
    Score: 0.287
  32. Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochem Pharmacol. 2014 Apr 15; 88(4):671-6.
    View in: PubMed
    Score: 0.279
  33. Rosen AC, Ashford JW, Perry G. Ethics review as a catalyst for progress. J Alzheimers Dis. 2014; 40(2):233-5.
    View in: PubMed
    Score: 0.278
  34. Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. J Alzheimers Dis. 2014; 40 Suppl 1:S5.
    View in: PubMed
    Score: 0.278
  35. Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiol Dis. 2013 Nov; 59:100-10.
    View in: PubMed
    Score: 0.269
  36. Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface. Alzheimer's disease: advances for a new century. J Alzheimers Dis. 2013; 33 Suppl 1:S1.
    View in: PubMed
    Score: 0.260
  37. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57.
    View in: PubMed
    Score: 0.258
  38. Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res. 2012 Nov; 43(8):694-8.
    View in: PubMed
    Score: 0.256
  39. Liu G, Men P, Zhu X, Perry G. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease. Ther Deliv. 2012 May; 3(5):571-4.
    View in: PubMed
    Score: 0.248
  40. Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. J Neurochem. 2012 Mar; 120(6):1139-40.
    View in: PubMed
    Score: 0.243
  41. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704.
    View in: PubMed
    Score: 0.240
  42. Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. Int J Exp Pathol. 2011 Oct; 92(5):297-8.
    View in: PubMed
    Score: 0.238
  43. Perry G, Zhu X. Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease. J Alzheimers Dis. 2011; 24(1):1-2.
    View in: PubMed
    Score: 0.226
  44. Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, Kennedy D, Weiner M, Perry G. Imaging the Alzheimer brain. J Alzheimers Dis. 2011; 26 Suppl 3:1-27.
    View in: PubMed
    Score: 0.226
  45. Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1201-8.
    View in: PubMed
    Score: 0.218
  46. Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1209-18.
    View in: PubMed
    Score: 0.218
  47. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010; 610:419-34.
    View in: PubMed
    Score: 0.211
  48. Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010; 19(1):363-72.
    View in: PubMed
    Score: 0.211
  49. Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7.
    View in: PubMed
    Score: 0.210
  50. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta. 2010 Jan; 1802(1):2-10.
    View in: PubMed
    Score: 0.208
  51. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40.
    View in: PubMed
    Score: 0.207
  52. Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-1406.
    View in: PubMed
    Score: 0.200
  53. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66.
    View in: PubMed
    Score: 0.199
  54. Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009 Feb; 43(2):156-64.
    View in: PubMed
    Score: 0.198
  55. Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem. 2008 Nov; 8(13):1395-406.
    View in: PubMed
    Score: 0.194
  56. Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets. 2008 Feb; 7(1):3-10.
    View in: PubMed
    Score: 0.185
  57. Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med. 2008 Apr 15; 44(8):1493-505.
    View in: PubMed
    Score: 0.184
  58. Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30.
    View in: PubMed
    Score: 0.183
  59. Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets. 2007 Dec; 6(6):411-23.
    View in: PubMed
    Score: 0.182
  60. Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep; 64(17):2202-10.
    View in: PubMed
    Score: 0.179
  61. Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis. 2007 Sep; 12(2):195-206.
    View in: PubMed
    Score: 0.179
  62. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 2007 Nov-Dec; 3(6):614-5.
    View in: PubMed
    Score: 0.179
  63. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol. 2007 Jun; 66(6):525-32.
    View in: PubMed
    Score: 0.176
  64. Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May; 32(4-5):717-22.
    View in: PubMed
    Score: 0.173
  65. Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 Jun 15; 257(1-2):240-6.
    View in: PubMed
    Score: 0.173
  66. Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev Med Chem. 2007 Feb; 7(2):171-80.
    View in: PubMed
    Score: 0.172
  67. Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Rev Neurother. 2006 Jun; 6(6):897-910.
    View in: PubMed
    Score: 0.164
  68. Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mech Ageing Dev. 2006 Jun; 127(6):501-6.
    View in: PubMed
    Score: 0.162
  69. Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101.
    View in: PubMed
    Score: 0.160
  70. Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radic Biol Med. 2006 Mar 01; 40(5):737-9.
    View in: PubMed
    Score: 0.160
  71. Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res. 2006; 39(1):7-13.
    View in: PubMed
    Score: 0.160
  72. Perry G. Solving the insoluble. J Alzheimers Dis. 2006; 9(3 Suppl):301-4.
    View in: PubMed
    Score: 0.160
  73. Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res. 2005 Oct; 2(4):403-8.
    View in: PubMed
    Score: 0.157
  74. Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends Mol Med. 2005 Sep; 11(9):391-3.
    View in: PubMed
    Score: 0.156
  75. Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? J Alzheimers Dis. 2005 Jun; 7(3):247-53; discussion 255-62.
    View in: PubMed
    Score: 0.153
  76. Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging. 2005 May; 26(5):579-80.
    View in: PubMed
    Score: 0.152
  77. Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Curr Neurovasc Res. 2005 Apr; 2(2):179-84.
    View in: PubMed
    Score: 0.152
  78. Liu Q, Smith MA, Avil? J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med. 2005 Mar 15; 38(6):746-54.
    View in: PubMed
    Score: 0.151
  79. Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem. 2005 Jun 03; 280(22):20978-86.
    View in: PubMed
    Score: 0.151
  80. Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochim Biophys Acta. 2005 Jan 03; 1739(2-3):211-5.
    View in: PubMed
    Score: 0.149
  81. Moreira PI, Smith MA, Zhu X, Honda K, Lee HG, Aliev G, Perry G. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful? Drug News Perspect. 2005 Jan-Feb; 18(1):13-9.
    View in: PubMed
    Score: 0.149
  82. Moreira PI, Siedlak SL, Aliev G, Zhu X, Cash AD, Smith MA, Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. J Neural Transm (Vienna). 2005 Jul; 112(7):921-32.
    View in: PubMed
    Score: 0.148
  83. Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. Am J Pathol. 2004 Nov; 165(5):1461-4.
    View in: PubMed
    Score: 0.147
  84. Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer's disease. Expert Rev Neurother. 2004 Nov; 4(6):995-1004.
    View in: PubMed
    Score: 0.147
  85. de la Torre J, Aliev G, Perry G. Drug therapy in Alzheimer's disease. N Engl J Med. 2004 Oct 28; 351(18):1911-3; author reply 1911-3.
    View in: PubMed
    Score: 0.147
  86. Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis. 2004 Oct; 17(1):108-13.
    View in: PubMed
    Score: 0.146
  87. H?ilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Donanemab, another anti-Alzheimer's drug with risk and uncertain benefit. Ageing Res Rev. 2024 Aug; 99:102348.
    View in: PubMed
    Score: 0.143
  88. Casadesus G, Smith MA, Zhu X, Aliev G, Cash AD, Honda K, Petersen RB, Perry G. Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species. J Alzheimers Dis. 2004 Apr; 6(2):165-9.
    View in: PubMed
    Score: 0.141
  89. H?ilund-Carlsen PF, Alavi A, Castellani RJ, Neve RL, Perry G, Revheim ME, Barrio JR. Alzheimer's Amyloid Hypothesis and Antibody Therapy: Melting Glaciers? Int J Mol Sci. 2024 Mar 31; 25(7).
    View in: PubMed
    Score: 0.141
  90. Everett J, Brooks J, Tjendana Tjhin V, Lermyte F, Hands-Portman I, Plascencia-Villa G, Perry G, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues. ACS Chem Neurosci. 2024 04 03; 15(7):1469-1483.
    View in: PubMed
    Score: 0.141
  91. Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, Perry G. Oxidative stress signalling in Alzheimer's disease. Brain Res. 2004 Mar 12; 1000(1-2):32-9.
    View in: PubMed
    Score: 0.141
  92. Ghanbari HA, Ghanbari K, Harris PL, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell. 2004 02; 3(1):41-4.
    View in: PubMed
    Score: 0.140
  93. Garc?a-Carlos CA, Basurto-Islas G, Perry G, Mondrag?n-Rodr?guez S. Meta-Analysis in Transgenic Alzheimer's Disease Mouse Models Reveals Opposite Brain Network Effects of Amyloid-? and Phosphorylated Tau Proteins. J Alzheimers Dis. 2024; 99(2):595-607.
    View in: PubMed
    Score: 0.139
  94. H?ilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village. Ageing Res Rev. 2024 01; 93:102173.
    View in: PubMed
    Score: 0.139
  95. Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS. Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927.
    View in: PubMed
    Score: 0.137
  96. Perry G, Nunomura A, Raina AK, Aliev G, Siedlak SL, Harris PL, Casadesus G, Petersen RB, Bligh-Glover W, Balraj E, Petot GJ, Smith MA. A metabolic basis for Alzheimer disease. Neurochem Res. 2003 Oct; 28(10):1549-52.
    View in: PubMed
    Score: 0.137
  97. Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurol Res. 2003 Sep; 25(6):665-74.
    View in: PubMed
    Score: 0.136
  98. Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathol. 2003 Dec; 106(6):552-6.
    View in: PubMed
    Score: 0.136
  99. Liu Q, Raina AK, Smith MA, Sayre LM, Perry G. Hydroxynonenal, toxic carbonyls, and Alzheimer disease. Mol Aspects Med. 2003 Aug-Oct; 24(4-5):305-13.
    View in: PubMed
    Score: 0.135
  100. Petrovic N, Essack M, ?ami A, Perry G, Gojobori T, Isenovic ER, Bajic VP. MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may unravel targets for the AD/BC comorbidity treatment. Comput Biol Chem. 2023 Oct; 106:107925.
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    Score: 0.135
  101. H?ilund-Carlsen PF, Revheim ME, Costa T, Alavi A, Kepp KP, Sensi SL, Perry G, Robakis NK, Barrio JR, Vissel B. Passive Alzheimer's immunotherapy: A promising or uncertain option? Ageing Res Rev. 2023 09; 90:101996.
    View in: PubMed
    Score: 0.134
  102. Lathe R, Schultek NM, Balin BJ, Ehrlich GD, Auber LA, Perry G, Breitschwerdt EB, Corry DB, Doty RL, Rissman RA, Nara PL, Itzhaki R, Eimer WA, Tanzi RE. Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for collaboration. Alzheimers Dement. 2023 11; 19(11):5209-5231.
    View in: PubMed
    Score: 0.134
  103. Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Av?la J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol. 2003 May; 162(5):1623-7.
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    Score: 0.133
  104. Wang W, Zhao F, Lu Y, Siedlak SL, Fujioka H, Feng H, Perry G, Zhu X. Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain. Acta Neuropathol Commun. 2023 03 31; 11(1):54.
    View in: PubMed
    Score: 0.132
  105. Hampel H, Hu Y, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The amyloid-? pathway in Alzheimer's disease: a plain language summary. Neurodegener Dis Manag. 2023 06; 13(3):141-149.
    View in: PubMed
    Score: 0.132
  106. Shobeiri P, Alilou S, Jaberinezhad M, Zare F, Karimi N, Maleki S, Teixeira AL, Perry G, Rezaei N. Circulating long non-coding RNAs as novel diagnostic biomarkers for Alzheimer's disease (AD): A systematic review and meta-analysis. PLoS One. 2023; 18(3):e0281784.
    View in: PubMed
    Score: 0.132
  107. Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals. 2003 Mar; 16(1):77-81.
    View in: PubMed
    Score: 0.131
  108. Kepp KP, Sensi SL, Johnsen KB, Barrio JR, H?ilund-Carlsen PF, Neve RL, Alavi A, Herrup K, Perry G, Robakis NK, Vissel B, Espay AJ. The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes. J Alzheimers Dis. 2023; 94(2):497-507.
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    Score: 0.130
  109. Ding P, Gurney M, Perry G, Xu R. Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects. J Alzheimers Dis. 2023; 96(4):1711-1720.
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    Score: 0.130
  110. Aliev G, Smith MA, Obrenovich ME, de la Torre JC, Perry G. Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotox Res. 2003; 5(7):491-504.
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    Score: 0.130
  111. H?ilund-Carlsen PF, Alavi A, Perry G, Barrio JR. MRI Monitoring of Anti-Alzheimer Therapy Amyloid-Related Imaging Abnormalities: Due Diligence or Overkill? AJNR Am J Neuroradiol. 2023 01; 44(1):E4-E5.
    View in: PubMed
    Score: 0.129
  112. Perry G, Nunomura A, Hirai K, Zhu X, P?rez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 2002 Dec 01; 33(11):1475-9.
    View in: PubMed
    Score: 0.129
  113. Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Dec; 133(4):507-13.
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    Score: 0.129
  114. Smith MA, Casadesus G, Joseph JA, Perry G. Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic Biol Med. 2002 Nov 01; 33(9):1194-9.
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    Score: 0.128
  115. Smith MA, Atwood CS, Joseph JA, Perry G. Predicting the failure of amyloid-beta vaccine. Lancet. 2002 May 25; 359(9320):1864-5.
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    Score: 0.124
  116. Smith MA, Joseph JA, Atwood CS, Perry G. Dangers of the amyloid-beta vaccination. Acta Neuropathol. 2002 Jul; 104(1):110.
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    Score: 0.124
  117. Correia SC, Alves MG, Oliveira PF, Casadesus G, LaManna J, Perry G, Moreira PI. Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria. Antioxid Redox Signal. 2022 Oct; 37(10-12):739-757.
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    Score: 0.124
  118. Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochem Int. 2002 May; 40(6):527-31.
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    Score: 0.124
  119. Mirzayi P, Shobeiri P, Kalantari A, Perry G, Rezaei N. Optogenetics: implications for Alzheimer's disease research and therapy. Mol Brain. 2022 02 23; 15(1):20.
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    Score: 0.122
  120. Whitehouse P, Gandy S, Saini V, George DR, Larson EB, Alexander GC, Avorn J, Brownlee S, Camp C, Chertkow H, Fugh-Berman A, Howard R, Kesselheim A, Langa KM, Perry G, Richard E, Schneider L. Making the Case for Accelerated Withdrawal of Aducanumab. J Alzheimers Dis. 2022; 87(3):1003-1007.
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    Score: 0.121
  121. Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. J Neural Transm Suppl. 2002; (62):69-75.
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    Score: 0.121
  122. Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J Biol Chem. 2002 Feb 15; 277(7):4644-8.
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    Score: 0.120
  123. Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R. Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Alzheimers Res Ther. 2021 10 20; 13(1):177.
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    Score: 0.119
  124. Mahdiabadi S, Momtazmanesh S, Perry G, Rezaei N. Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review. Rev Neurosci. 2022 06 27; 33(4):365-381.
    View in: PubMed
    Score: 0.118
  125. Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The Amyloid-? Pathway in Alzheimer's Disease. Mol Psychiatry. 2021 10; 26(10):5481-5503.
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    Score: 0.118
  126. Pappolla MA, Perry G, Fang X, Zagorski M, Sambamurti K, Poeggeler B. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Neurobiol Dis. 2021 08; 156:105403.
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    Score: 0.116
  127. Hampel H, Nistic? R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucia A, Urbani A, Sancesario GM, Mapstone M, Corbo M, Vergallo A, Lista S. Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing Res Rev. 2021 08; 69:101346.
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    Score: 0.115
  128. ?ivkovic L, Bajic V, Cabarkapa-Pirkovic A, Dekanski D, Forbes-Hern?ndez TY, Zlatkovic-?venda M, Perry G, Spremo-Potparevic B. Strawberry (Fragaria ananassa duch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer's disease. J Food Biochem. 2021 04; 45(4):e13637.
    View in: PubMed
    Score: 0.114
  129. Momtazmanesh S, Perry G, Rezaei N. Toll-like receptors in Alzheimer's disease. J Neuroimmunol. 2020 11 15; 348:577362.
    View in: PubMed
    Score: 0.110
  130. Smith MA, Rottkamp CA, Nunomura A, Raina AK, Perry G. Oxidative stress in Alzheimer's disease. Biochim Biophys Acta. 2000 Jul 26; 1502(1):139-44.
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    Score: 0.110
  131. Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. Int J Dev Neurosci. 2000 Jul-Aug; 18(4-5):417-21.
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    Score: 0.109
  132. Gonz?lez-S?nchez M, Bartolome F, Antequera D, Puertas-Mart?n V, Gonz?lez P, G?mez-Grande A, Llamas-Velasco S, Herrero-San Mart?n A, P?rez-Mart?nez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Iba?ez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834.
    View in: PubMed
    Score: 0.109
  133. Veurink G, Perry G, Singh SK. Role of antioxidants and a nutrient rich diet in Alzheimer's disease. Open Biol. 2020 06; 10(6):200084.
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    Score: 0.109
  134. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30.
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    Score: 0.108
  135. Friedland RP, Shi J, Lamanna JC, Smith MA, Perry G. Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease. Ann N Y Acad Sci. 2000 Apr; 903:123-8.
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    Score: 0.107
  136. Perry G, Raina AK, Nunomura A, Wataya T, Sayre LM, Smith MA. How important is oxidative damage? Lessons from Alzheimer's disease. Free Radic Biol Med. 2000 Mar 01; 28(5):831-4.
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    Score: 0.107
  137. Perry G, Nunomura A, Raina AK, Smith MA. Amyloid-beta junkies. Lancet. 2000 Feb 26; 355(9205):757.
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    Score: 0.107
  138. Smith MA, Joseph JA, Perry G. Arson. Tracking the culprit in Alzheimer's disease. Ann N Y Acad Sci. 2000; 924:35-8.
    View in: PubMed
    Score: 0.105
  139. Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):413-20.
    View in: PubMed
    Score: 0.105
  140. Kim HT, Russell RL, Raina AK, Harris PL, Siedlak SL, Zhu X, Petersen RB, Shimohama S, Smith MA, Perry G. Protein disulfide isomerase in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):485-9.
    View in: PubMed
    Score: 0.105
  141. Hernandes-Alejandro M, Monta?o S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, P?rez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres M?, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(2):553-569.
    View in: PubMed
    Score: 0.105
  142. Reyes-Pablo AE, Campa-C?rdoba BB, Luna-Viramontes NI, Ontiveros-Torres M?, Villanueva-Fierro I, Bravo-Mu?oz M, S?enz-Ibarra B, Barbosa O, Guadarrama-Ort?z P, Garc?s-Ram?rez L, de la Cruz F, Harrington CR, Mart?nez-Robles S, Gonz?lez-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in M?xico. J Alzheimers Dis. 2020; 76(3):853-862.
    View in: PubMed
    Score: 0.105
  143. Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580.
    View in: PubMed
    Score: 0.104
  144. Russell RL, Siedlak SL, Raina AK, Bautista JM, Smith MA, Perry G. Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease. Arch Biochem Biophys. 1999 Oct 15; 370(2):236-9.
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    Score: 0.104
  145. Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 Aug 02; 10(11):2411-5.
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    Score: 0.102
  146. Castellani RJ, Smith MA, Nunomura A, Harris PL, Perry G. Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin? Free Radic Biol Med. 1999 Jun; 26(11-12):1508-12.
    View in: PubMed
    Score: 0.101
  147. Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA, Schwarzschild MA, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337.
    View in: PubMed
    Score: 0.099
  148. Perry G, Smith MA. [Is the lesion produced by oxidation a central part in the pathogenesis of Alzheimer's disease?]. Neurologia. 1999 Feb; 14(2):78-84.
    View in: PubMed
    Score: 0.099
  149. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289.
    View in: PubMed
    Score: 0.098
  150. Hampel H, Vergallo A, Perry G, Lista S. The Alzheimer Precision Medicine Initiative. J Alzheimers Dis. 2019; 68(1):1-24.
    View in: PubMed
    Score: 0.098
  151. Hampel H, Lista S, Mango D, Nistic? R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A. Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. J Alzheimers Dis. 2019; 69(3):615-629.
    View in: PubMed
    Score: 0.098
  152. Velasco ME, Smith MA, Siedlak SL, Nunomura A, Perry G. Striation is the characteristic neuritic abnormality in Alzheimer disease. Brain Res. 1998 Dec 07; 813(2):329-33.
    View in: PubMed
    Score: 0.098
  153. Smith MA, Perry G. What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease? J Chem Neuroanat. 1998 Dec; 16(1):35-41.
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    Score: 0.098
  154. Smith MA, Vas?k M, Knipp M, Castellani RJ, Perry G. Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease. Free Radic Biol Med. 1998 Nov 15; 25(8):898-902.
    View in: PubMed
    Score: 0.097
  155. Perry G, Nunomura A, Lucassen P, Lassmann H, Smith MA. Apoptosis and Alzheimer's disease. Science. 1998 Nov 13; 282(5392):1268-9.
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    Score: 0.097
  156. Pinho TS, Correia SC, Perry G, Ambr?sio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2048-2059.
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    Score: 0.097
  157. Hern?ndez F, Cuadros R, Oll? I, Garc?a C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030.
    View in: PubMed
    Score: 0.096
  158. Perry G, Nunomura A, Smith MA. A suicide note from Alzheimer disease neurons? Nat Med. 1998 Aug; 4(8):897-8.
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    Score: 0.096
  159. Everett J, Collingwood JF, Tjendana-Tjhin V, Brooks J, Lermyte F, Plascencia-Villa G, Hands-Portman I, Dobson J, Perry G, Telling ND. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale. 2018 Jul 05; 10(25):11782-11796.
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    Score: 0.095
  160. Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G. Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem. 1998 Jun; 46(6):731-5.
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    Score: 0.094
  161. Perry G, Smith MA. Is oxidative damage central to the pathogenesis of Alzheimer disease? Acta Neurol Belg. 1998 Jun; 98(2):175-9.
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    Score: 0.094
  162. Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PL, Siedlak SL, Tabaton M, Perry G. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem. 1998 May; 70(5):2212-5.
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    Score: 0.094
  163. Perry G, Smith MA, McCann CE, Siedlak SL, Jones PK, Friedland RP. Cerebrovascular muscle atrophy is a feature of Alzheimer's disease. Brain Res. 1998 Apr 27; 791(1-2):63-6.
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    Score: 0.094
  164. Mondrag?n-Rodr?guez S, Salas-Gallardo A, Gonz?lez-Pereyra P, Mac?as M, Ordaz B, Pe?a-Ortega F, Aguilar-V?zquez A, Orta-Salazar E, D?az-Cintra S, Perry G, Williams S. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. J Biol Chem. 2018 06 01; 293(22):8462-8472.
    View in: PubMed
    Score: 0.093
  165. Smith MA, Wehr K, Harris PL, Siedlak SL, Connor JR, Perry G. Abnormal localization of iron regulatory protein in Alzheimer's disease. Brain Res. 1998 Mar 30; 788(1-2):232-6.
    View in: PubMed
    Score: 0.093
  166. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 04; 130:331-365.
    View in: PubMed
    Score: 0.093
  167. Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. ACS Chem Neurosci. 2018 04 18; 9(4):708-714.
    View in: PubMed
    Score: 0.092
  168. Manyevitch R, Protas M, Scarpiello S, Deliso M, Bass B, Nanajian A, Chang M, Thompson SM, Khoury N, Gonnella R, Trotz M, Moore DB, Harms E, Perry G, Clunes L, Ortiz A, Friedrich JO, Murray IVJ. Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers. Curr Alzheimer Res. 2018; 15(2):164-181.
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    Score: 0.092
  169. Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. J Alzheimers Dis. 2018; 63(1):157-165.
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    Score: 0.092
  170. Frank L, Wesson Ashford J, Bayley PJ, Borson S, Buschke H, Cohen D, Cummings JL, Davies P, Dean M, Finkel SI, Hyer L, Perry G, Powers RE, Schmitt F. Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle. J Alzheimers Dis. 2018; 66(2):421-423.
    View in: PubMed
    Score: 0.092
  171. Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens. Free Radic Biol Med. 2018 02 01; 115:351-360.
    View in: PubMed
    Score: 0.091
  172. Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Mu?oz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to ? sheet in tau protein linked to Alzheimer's disease. J Enzyme Inhib Med Chem. 2017 Dec; 32(1):945-953.
    View in: PubMed
    Score: 0.091
  173. Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131.
    View in: PubMed
    Score: 0.091
  174. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev. 2017; 2017:9302761.
    View in: PubMed
    Score: 0.090
  175. Smith MA, Harris PL, Sayre LM, Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9866-8.
    View in: PubMed
    Score: 0.090
  176. Sayre LM, Zagorski MG, Surewicz WK, Krafft GA, Perry G. Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal. Chem Res Toxicol. 1997 May; 10(5):518-26.
    View in: PubMed
    Score: 0.088
  177. Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci. 1997 Apr 15; 17(8):2653-7.
    View in: PubMed
    Score: 0.087
  178. Doens D, Valiente PA, Mfuh AM, X T Vo A, Tristan A, Carre?o L, Quijada M, Nguyen VT, Perry G, Larionov OV, Lleonart R, Fern?ndez PL. Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. ACS Chem Neurosci. 2017 06 21; 8(6):1232-1241.
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    Score: 0.086
  179. Smith MA, Perry G. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J Neuropathol Exp Neurol. 1997 Feb; 56(2):217.
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    Score: 0.086
  180. Mondrag?n-Rodr?guez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46.
    View in: PubMed
    Score: 0.086
  181. Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1027-1033.
    View in: PubMed
    Score: 0.086
  182. Smith MA, Tabaton M, Perry G. Early contribution of oxidative glycation in Alzheimer disease. Neurosci Lett. 1996 Oct 18; 217(2-3):210-1.
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    Score: 0.084
  183. Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochim Biophys Acta. 2016 10; 1862(10):1909-17.
    View in: PubMed
    Score: 0.083
  184. Pistollato F, Ohayon EL, Lam A, Langley GR, Novak TJ, Pamies D, Perry G, Trushina E, Williams RS, Roher AE, Hartung T, Harnad S, Barnard N, Morris MC, Lai MC, Merkley R, Chandrasekera PC. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. Oncotarget. 2016 Jun 28; 7(26):38999-39016.
    View in: PubMed
    Score: 0.083
  185. Smith MA, Sayre LM, Monnier VM, Perry G. Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol Chem Neuropathol. 1996 May-Aug; 28(1-3):41-8.
    View in: PubMed
    Score: 0.082
  186. Smith MA, Siedlak SL, Richey PL, Nagaraj RH, Elhammer A, Perry G. Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease. Brain Res. 1996 Apr 22; 717(1-2):99-108.
    View in: PubMed
    Score: 0.082
  187. Ontiveros-Torres M?, Labra-Barrios ML, D?az-Cintra S, Aguilar-V?zquez AR, Moreno-Campuzano S, Flores-Rodr?guez P, Luna-Herrera C, Mena R, Perry G, Flor?n-Gardu?o B, Luna-Mu?oz J, Luna-Arias JP. Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse. J Alzheimers Dis. 2016 03 22; 52(1):243-69.
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    Score: 0.081
  188. Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016 Feb 03; 6:20352.
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    Score: 0.080
  189. Smith MA, Sayre LM, Perry G. Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link. Diabetologia. 1996 Feb; 39(2):247.
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    Score: 0.080
  190. Smith MA, Dunbar CE, Miller EJ, Perry G. Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor. Mol Chem Neuropathol. 1996 Feb; 27(2):145-54.
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    Score: 0.080
  191. Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. ACS Chem Neurosci. 2016 Mar 16; 7(3):261-8.
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    Score: 0.080
  192. Praprotnik D, Smith MA, Richey PL, Vinters HV, Perry G. Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress. Acta Neuropathol. 1996; 91(1):1-5.
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    Score: 0.080
  193. Praprotnik D, Smith MA, Richey PL, Vinters HV, Perry G. Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease. Acta Neuropathol. 1996; 91(3):226-35.
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    Score: 0.080
  194. Smith MA, Perry G. Alzheimer disease: protein-protein interaction and oxidative stress. Bol Estud Med Biol. 1996 Jan-Dec; 44(1-4):5-10.
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    Score: 0.080
  195. Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, L?vheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA. Microbes and Alzheimer's Disease. J Alzheimers Dis. 2016; 51(4):979-84.
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    Score: 0.080
  196. Mart?n-Maestro P, Gargini R, Perry G, Avila J, Garc?a-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet. 2016 Feb 15; 25(4):792-806.
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    Score: 0.080
  197. Smith MA, Perry G. Free radical damage, iron, and Alzheimer's disease. J Neurol Sci. 1995 Dec; 134 Suppl:92-4.
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    Score: 0.079
  198. Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71.
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    Score: 0.079
  199. Smith MA, Monnier VM, Sayre LM, Perry G. Amyloidosis, advanced glycation end products and Alzheimer disease. Neuroreport. 1995 Aug 21; 6(12):1595-6.
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    Score: 0.078
  200. Smith MA, Rudnicka-Nawrot M, Richey PL, Praprotnik D, Mulvihill P, Miller CA, Sayre LM, Perry G. Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease. J Neurochem. 1995 Jun; 64(6):2660-6.
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    Score: 0.077
  201. Rifenburg RP, Perry G. Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease. Neurodegeneration. 1995 Jun; 4(2):235-7.
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    Score: 0.077
  202. Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Mart?nez-Mart?n P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model. ACS Chem Neurosci. 2015 Aug 19; 6(8):1393-1399.
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    Score: 0.076
  203. Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995 Apr; 18(4):172-6.
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    Score: 0.076
  204. Smith MA, Sayre LM, Vitek MP, Monnier VM, Perry G. Early AGEing and Alzheimer's. Nature. 1995 Mar 23; 374(6520):316.
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    Score: 0.076
  205. Richey PL, Siedlak SL, Smith MA, Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):657-63.
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    Score: 0.076
  206. Smith MA, Richey PL, Kutty RK, Wiggert B, Perry G. Ultrastructural localization of heme oxygenase-1 to the neurofibrillary pathology of Alzheimer disease. Mol Chem Neuropathol. 1995 Feb-Apr; 24(2-3):227-30.
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    Score: 0.075
  207. Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. J Neural Transm (Vienna). 2016 Feb; 123(2):107-11.
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    Score: 0.075
  208. Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease. Acta Neuropathol. 1995; 89(4):291-5.
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    Score: 0.075
  209. Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. J Alzheimers Dis. 2015; 44(2):549-60.
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    Score: 0.075
  210. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. J Alzheimers Dis. 2015; 46(1):271-83.
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    Score: 0.075
  211. Luna-Mu?oz J, Perry G, Guevara J. Ra?l Mena: 1953-2014. J Alzheimers Dis. 2015; 45(2):325-7.
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    Score: 0.075
  212. Spremo-Potparevic B, Bajic V, Perry G, Zivkovic L. Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients. Curr Alzheimer Res. 2015; 12(10):990-6.
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    Score: 0.075
  213. Gambetti P, Perry G. Alzheimer's disease and prion proteins: a meeting made in muscle. Am J Pathol. 1994 Dec; 145(6):1261-4.
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    Score: 0.074
  214. Smith MA, Richey PL, Taneda S, Kutty RK, Sayre LM, Monnier VM, Perry G. Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease. Ann N Y Acad Sci. 1994 Nov 17; 738:447-54.
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    Score: 0.074
  215. Smith MA, Kutty RK, Richey PL, Yan SD, Stern D, Chader GJ, Wiggert B, Petersen RB, Perry G. Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. Am J Pathol. 1994 Jul; 145(1):42-7.
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    Score: 0.072
  216. Smith MA, Taneda S, Richey PL, Miyata S, Yan SD, Stern D, Sayre LM, Monnier VM, Perry G. Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5710-4.
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    Score: 0.072
  217. Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neurosci Bull. 2014 Apr; 30(2):243-52.
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    Score: 0.071
  218. Smith MA, Perry G. Alzheimer disease: an imbalance of proteolytic regulation? Med Hypotheses. 1994 Apr; 42(4):277-9.
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    Score: 0.071
  219. Mondrag?n-Rodr?guez S, Perry G, Luna-Mu?oz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35.
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    Score: 0.070
  220. Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Curr Alzheimer Res. 2014 Feb; 11(2):165-74.
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    Score: 0.070
  221. Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Curr Alzheimer Res. 2014; 11(10):928-40.
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    Score: 0.070
  222. Kalaria RN, Perry G. Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease. Brain Res. 1993 Dec 17; 631(1):151-5.
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    Score: 0.069
  223. Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Transl Psychiatry. 2013 Dec 03; 3:e332.
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    Score: 0.069
  224. Perry G, Richey PL, Siedlak SL, Smith MA, Mulvihill P, DeWitt DA, Barnett J, Greenberg BD, Kalaria RN. Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease. Am J Pathol. 1993 Dec; 143(6):1586-93.
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    Score: 0.069
  225. Jarero-Basulto JJ, Luna-Mu?oz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61.
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    Score: 0.069
  226. Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta. 2014 Aug; 1842(8):1240-7.
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    Score: 0.069
  227. Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):70-8.
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    Score: 0.069
  228. Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide ?-defensin-1 expression is upregulated in Alzheimer's brain. J Neuroinflammation. 2013 Oct 18; 10:127.
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    Score: 0.069
  229. Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? J Neurochem. 2013 Oct; 127(1):4-6.
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    Score: 0.068
  230. Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg BD, Perry G. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Res. 1993 Sep 24; 623(1):142-6.
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    Score: 0.068
  231. Kalaria RN, Golde T, Kroon SN, Perry G. Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. Am J Pathol. 1993 Sep; 143(3):886-93.
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    Score: 0.068
  232. Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72.
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    Score: 0.068
  233. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxid Med Cell Longev. 2013; 2013:940603.
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    Score: 0.067
  234. Smith MA, Kalaria RN, Perry G. Alpha 1-trypsin immunoreactivity in Alzheimer disease. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):579-84.
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    Score: 0.067
  235. Garc?a-Escudero V, Mart?n-Maestro P, Perry G, Avila J. Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev. 2013; 2013:162152.
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    Score: 0.067
  236. DeWitt DA, Silver J, Canning DR, Perry G. Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease. Exp Neurol. 1993 Jun; 121(2):149-52.
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    Score: 0.067
  237. Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res. 2013 May 01; 10(4):406-19.
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    Score: 0.066
  238. Perry G. Neuritic plaques in Alzheimer disease originate from neurofibrillary tangles. Med Hypotheses. 1993 Apr; 40(4):257-8.
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    Score: 0.066
  239. Dur?n-Gonz?lez J, Michi ED, Elorza B, Perez-C?rdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging. 2013 Aug; 34(8):2071-6.
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    Score: 0.066
  240. Zivkovic L, Spremo-Potparevic B, Siedlak SL, Perry G, Pleca?-Solarovic B, Milicevic Z, Bajic VP. DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neurodegener Dis. 2013; 12(3):156-63.
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    Score: 0.065
  241. Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62.
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    Score: 0.065
  242. Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Curr Alzheimer Res. 2013 Jan; 10(1):108-16.
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    Score: 0.065
  243. Hou L, Lee HG, Han F, Tedesco JM, Perry G, Smith MA, Zagorski MG. Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation. J Alzheimers Dis. 2013; 37(1):9-18.
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    Score: 0.065
  244. Coskuner O, Wise-Scira O, Perry G, Kitahara T. The structures of the E22? mutant-type amyloid-? alloforms and the impact of E22? mutation on the structures of the wild-type amyloid-? alloforms. ACS Chem Neurosci. 2013 Feb 20; 4(2):310-20.
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    Score: 0.065
  245. Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Pl?cido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7.
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    Score: 0.064
  246. Kalaria RN, Kroon SN, Grahovac I, Perry G. Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease. Neuroscience. 1992 Nov; 51(1):177-84.
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    Score: 0.064
  247. Kawai M, Cras P, Perry G. Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution. Brain Res. 1992 Oct 02; 592(1-2):278-82.
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    Score: 0.064
  248. Kawai M, Cras P, Richey P, Tabaton M, Lowery DE, Gonzalez-DeWhitt PA, Greenberg BD, Gambetti P, Perry G. Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease. Am J Pathol. 1992 Apr; 140(4):947-58.
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    Score: 0.062
  249. Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors. 2012 Mar-Apr; 38(2):133-8.
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    Score: 0.061
  250. Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41.
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    Score: 0.061
  251. Gollin PA, Kalaria RN, Eikelenboom P, Rozemuller A, Perry G. Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease. Neuroreport. 1992 Feb; 3(2):201-3.
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    Score: 0.061
  252. Perry G, Cras P, Siedlak SL, Tabaton M, Kawai M. Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease. Am J Pathol. 1992 Feb; 140(2):283-90.
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    Score: 0.061
  253. Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radic Res. 2012 Apr; 46(4):565-76.
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    Score: 0.061
  254. Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem. 2012 Feb; 120(3):419-29.
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    Score: 0.060
  255. Colom LV, Castaneda MT, Hernandez S, Perry G, Jaime S, Touhami A. Intrahippocampal amyloid-? (1-40) injections injure medial septal neurons in rats. Curr Alzheimer Res. 2011 Dec; 8(8):832-40.
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    Score: 0.060
  256. Perry G, Siedlak SL, Richey P, Kawai M, Cras P, Kalaria RN, Galloway PG, Scardina JM, Cordell B, Greenberg BD, et al. Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease. J Neurosci. 1991 Nov; 11(11):3679-83.
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    Score: 0.060
  257. Ziats NP, Petersen RB, Lee HG, Castellani RJ, Perry G, Zhu X. Mark A. Smith, 1965-2010: consummate student of pathogenesis. Int J Clin Exp Pathol. 2011; 4(7):731-2.
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    Score: 0.060
  258. Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Invest. 2011 Dec; 91(12):1777-86.
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    Score: 0.059
  259. Vande Weghe J, Cras P, Kawai M, Siedlak SL, Tabaton M, Greenberg B, Perry G. Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease. Brain Res. 1991 Sep 27; 560(1-2):303-5.
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    Score: 0.059
  260. Cras P, Kawai M, Siedlak S, Perry G. Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease. Brain Res. 1991 Sep 06; 558(2):312-4.
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    Score: 0.059
  261. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7552-6.
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    Score: 0.059
  262. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42.
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    Score: 0.059
  263. Siedlak SL, Cras P, Kawai M, Richey P, Perry G. Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease. J Histochem Cytochem. 1991 Jul; 39(7):899-904.
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    Score: 0.058
  264. Kalaria RN, Galloway PG, Perry G. Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders. Neuropathol Appl Neurobiol. 1991 Jun; 17(3):189-201.
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    Score: 0.058
  265. Perry G, Kawai M, Tabaton M, Onorato M, Mulvihill P, Richey P, Morandi A, Connolly JA, Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J Neurosci. 1991 Jun; 11(6):1748-55.
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    Score: 0.058
  266. Bonda DJ, Lee HG, Blair JA, Zhu X, Perry G, Smith MA. Role of metal dyshomeostasis in Alzheimer's disease. Metallomics. 2011 Mar; 3(3):267-70.
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    Score: 0.057
  267. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev. 2011 Apr; 10(2):264-73.
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    Score: 0.057
  268. Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. J Alzheimers Dis. 2011; 24 Suppl 2:1-2.
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    Score: 0.056
  269. Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, Zhu X. The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Curr Pharm Des. 2011; 17(31):3374-80.
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    Score: 0.056
  270. Kawai M, Kalaria RN, Harik SI, Perry G. The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathol. 1990 Dec; 137(6):1435-46.
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    Score: 0.056
  271. Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9.
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    Score: 0.056
  272. Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):241-6.
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    Score: 0.055
  273. Galloway PG, Mulvihill P, Siedlak S, Mijares M, Kawai M, Padget H, Kim R, Perry G. Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):291-300.
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    Score: 0.055
  274. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol. 2010 Jun 25; 3(6):570-81.
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    Score: 0.054
  275. Mondrag?n-Rodr?guez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev Neurother. 2010 May; 10(5):683-91.
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    Score: 0.054
  276. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010 Sep-Oct; 59(4-5):290-4.
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    Score: 0.054
  277. Bonda DJ, Lee HP, Lee HG, Friedlich AL, Perry G, Zhu X, Smith MA. Novel therapeutics for Alzheimer's disease: an update. Curr Opin Drug Discov Devel. 2010 Mar; 13(2):235-46.
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    Score: 0.053
  278. Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging. 2010 Mar 01; 27(3):181-92.
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    Score: 0.053
  279. Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomark Med. 2010 Feb; 4(1):15-26.
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    Score: 0.053
  280. Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96.
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    Score: 0.053
  281. Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol Biol. 2010; 610:123-44.
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    Score: 0.053
  282. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. J Alzheimers Dis. 2010; 20 Suppl 2:S401-12.
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    Score: 0.053
  283. Avila J, Perry G, Mart?nez-Mart?n P. Prospects on the origin of Alzheimer's disease. J Alzheimers Dis. 2010; 20(2):669-72.
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    Score: 0.053
  284. Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8.
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    Score: 0.053
  285. Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. J Alzheimers Dis. 2010; 22(3):771-5.
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    Score: 0.053
  286. Tabaton M, Perry G, Zhu X, Lee HG, Casadesus G, Smith MA. Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease. Am J Pathol. 2010 Feb; 176(2):540-1.
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    Score: 0.053
  287. Liu G, Men P, Perry G, Smith MA. Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease. Prog Brain Res. 2009; 180:97-108.
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    Score: 0.052
  288. Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev Neurother. 2009 Nov; 9(11):1615-21.
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    Score: 0.052
  289. Gustaw-Rothenberg KA, Siedlak SL, Bonda DJ, Lerner A, Tabaton M, Perry G, Smith MA. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol. 2010 Jan; 45(1):47-52.
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    Score: 0.052
  290. Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103.
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    Score: 0.051
  291. Dwyer BE, Stone ML, Gorman N, Sinclair PR, Perry G, Smith MA, Zhu X. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease. Neurosci Lett. 2009 Sep 25; 461(3):302-5.
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    Score: 0.051
  292. Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4.
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    Score: 0.051
  293. Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem. 2009 May; 109 Suppl 1:153-9.
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    Score: 0.050
  294. Perry G, Mulvihill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease. J Neurochem. 1989 May; 52(5):1523-8.
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    Score: 0.050
  295. Mulvihill P, Perry G. Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau. Brain Res. 1989 Apr 10; 484(1-2):150-6.
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    Score: 0.050
  296. Bonda DJ, Evans TA, Santocanale C, Llos? JC, Vi?a J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY). 2009 Apr; 1(4):382-8.
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    Score: 0.050
  297. Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90.
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    Score: 0.050
  298. Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochem Biophys Res Commun. 2009 Apr 24; 382(1):91-5.
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    Score: 0.050
  299. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Getting the iron out: phlebotomy for Alzheimer's disease? Med Hypotheses. 2009 May; 72(5):504-9.
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    Score: 0.049
  300. Perry G, Siedlak S, Mulvihill P, Kancherla M, Mijares M, Kawai M, Gambetti P, Sharma S, Maggiora L, Cornette J, et al. Immunolocalization of the amyloid precursor protein within the senile plaque. Prog Clin Biol Res. 1989; 317:1021-5.
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    Score: 0.049
  301. Onorato M, Mulvihill P, Connolly J, Galloway P, Whitehouse P, Perry G. Alteration of neuritic cytoarchitecture in Alzheimer disease. Prog Clin Biol Res. 1989; 317:781-9.
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    Score: 0.049
  302. Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):731-40.
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    Score: 0.049
  303. Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):763-74.
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    Score: 0.049
  304. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009; 18(3):483-507.
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    Score: 0.049
  305. Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis. 2009; 18(2):447-52.
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    Score: 0.049
  306. Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int. 2009 Feb; 54(2):84-8.
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    Score: 0.049
  307. Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res. 2008 Dec; 5(6):525-32.
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    Score: 0.049
  308. Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis. 2008 Dec; 15(4):615-24.
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    Score: 0.049
  309. Galloway PG, Grundke-Iqbal I, Iqbal K, Perry G. Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles. J Neuropathol Exp Neurol. 1988 Nov; 47(6):654-63.
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    Score: 0.049
  310. Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, M?ndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. J Cell Mol Med. 2009 May; 13(5):853-65.
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    Score: 0.048
  311. Marlatt MW, Lucassen PJ, Perry G, Smith MA, Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. J Alzheimers Dis. 2008 Oct; 15(2):199-210.
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    Score: 0.048
  312. Perry G, Lipphardt S, Mulvihill P, Kancherla M, Mijares M, Gambetti P, Sharma S, Maggiora L, Cornette J, Lobl T, et al. Amyloid precursor protein in senile plaques of Alzheimer disease. Lancet. 1988 Sep 24; 2(8613):746.
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    Score: 0.048
  313. Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol. 2008 Jun; 67(6):523-31.
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    Score: 0.047
  314. Collingwood JF, Chong RK, Kasama T, Cervera-Gontard L, Dunin-Borkowski RE, Perry G, P?sfai M, Siedlak SL, Simpson ET, Smith MA, Dobson J. Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. J Alzheimers Dis. 2008 Jun; 14(2):235-45.
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    Score: 0.047
  315. Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. J Neurochem. 2008 Aug; 106(3):1350-6.
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    Score: 0.047
  316. Mondrag?n-Rodr?guez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, Garc?a-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90.
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    Score: 0.047
  317. Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother. 2008 Apr-May; 62(4):199-207.
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    Score: 0.047
  318. Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Adv Clin Chem. 2008; 45:139-53.
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    Score: 0.046
  319. Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotox Res. 2007 Dec; 12(4):269-74.
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    Score: 0.046
  320. Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocr Metab Immune Disord Drug Targets. 2007 Dec; 7(4):300-3.
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    Score: 0.046
  321. Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):457-65.
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    Score: 0.045
  322. Perry G, Mulvihill P, Manetto V, Autilio-Gambetti L, Gambetti P. Immunocytochemical properties of Alzheimer straight filaments. J Neurosci. 1987 Nov; 7(11):3736-8.
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    Score: 0.045
  323. Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75.
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    Score: 0.045
  324. Webber KM, Perry G, Smith MA, Casadesus G. The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clin Med Res. 2007 Oct; 5(3):177-83.
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    Score: 0.045
  325. Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43(12):1569-73.
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    Score: 0.045
  326. Perry G, Friedman R, Kang DH, Manetto V, Autilio-Gambetti L, Gambetti P. Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions. Brain Res. 1987 Sep 15; 420(2):233-42.
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    Score: 0.045
  327. Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73.
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    Score: 0.044
  328. Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochem Res. 2007 Oct; 32(10):1640-5.
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    Score: 0.044
  329. Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. 2007 May 12; 4(3):140-5.
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    Score: 0.044
  330. Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci U S A. 1987 May; 84(9):3033-6.
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    Score: 0.044
  331. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9.
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    Score: 0.044
  332. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother. 2007 May; 7(5):473-85.
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    Score: 0.044
  333. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52.
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    Score: 0.044
  334. Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Curr Alzheimer Res. 2007 Feb; 4(1):67-72.
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    Score: 0.043
  335. Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9.
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    Score: 0.043
  336. Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61.
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    Score: 0.043
  337. Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4.
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    Score: 0.042
  338. Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007 Apr; 1772(4):494-502.
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    Score: 0.042
  339. Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Mol Cell Endocrinol. 2007 Jan 02; 260-262:271-5.
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    Score: 0.042
  340. Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochem Res. 2007 Apr-May; 32(4-5):639-44.
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    Score: 0.042
  341. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose! Am J Pathol. 2006 Sep; 169(3):738-9.
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    Score: 0.042
  342. Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6.
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    Score: 0.042
  343. Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett. 2006 Oct 09; 406(3):189-93.
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    Score: 0.042
  344. Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 Aug; 10(1):43-56.
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    Score: 0.042
  345. Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jul; 65(7):631-41.
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    Score: 0.041
  346. Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis. 2006 Jul; 9(2):147-53.
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    Score: 0.041
  347. Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G. Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. J Nutr Health Aging. 2006 Jul-Aug; 10(4):247-54.
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    Score: 0.041
  348. Forero DA, Casadesus G, Perry G, Arboleda H. Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J Cell Mol Med. 2006 Jul-Sep; 10(3):796-805.
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    Score: 0.041
  349. Lee HG, Perry G, Zhu X, Nunomura A, Smith MA. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression". Free Radic Biol Med. 2006 Jul 15; 41(2):188-9.
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    Score: 0.041
  350. Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10.
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    Score: 0.041
  351. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9.
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    Score: 0.041
  352. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30.
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    Score: 0.040
  353. Perry G, Selkoe DJ, Block BR, Stewart D, Autilio-Gambetti L, Gambetti P. Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments. J Neuropathol Exp Neurol. 1986 Mar; 45(2):161-8.
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    Score: 0.040
  354. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid beta: the alternate hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):75-80.
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    Score: 0.040
  355. Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Curr Pharm Des. 2006; 12(6):691-7.
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    Score: 0.040
  356. Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs Aging. 2006; 23(2):179.
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    Score: 0.040
  357. Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs R D. 2006; 7(3):187-93.
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    Score: 0.040
  358. Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25.
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    Score: 0.039
  359. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23.
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    Score: 0.039
  360. Liu G, Garrett MR, Men P, Zhu X, Perry G, Smith MA. Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochim Biophys Acta. 2005 Sep 25; 1741(3):246-52.
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    Score: 0.039
  361. Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Curr Neurovasc Res. 2005 Jul; 2(3):261-7.
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    Score: 0.039
  362. Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? Int J Exp Pathol. 2005 Jun; 86(3):133-8.
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    Score: 0.038
  363. Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Ann N Y Acad Sci. 2005 Jun; 1052:201-9.
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    Score: 0.038
  364. Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Ann N Y Acad Sci. 2005 Jun; 1043:545-52.
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    Score: 0.038
  365. Perry G, Rizzuto N, Autilio-Gambetti L, Gambetti P. Paired helical filaments from Alzheimer disease patients contain cytoskeletal components. Proc Natl Acad Sci U S A. 1985 Jun; 82(11):3916-20.
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    Score: 0.038
  366. Reddy VP, Garrett MR, Perry G, Smith MA. Carnosine: a versatile antioxidant and antiglycating agent. Sci Aging Knowledge Environ. 2005 May 04; 2005(18):pe12.
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    Score: 0.038
  367. Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med. 2005 Apr; 11(4):164-9.
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    Score: 0.038
  368. Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Dis Assoc Disord. 2005 Apr-Jun; 19(2):95-9.
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    Score: 0.038
  369. Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. J Neurosci Res. 2005 Feb 15; 79(4):554-60.
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    Score: 0.038
  370. Casadesus G, Atwood CS, Zhu X, Hartzler AW, Webber KM, Perry G, Bowen RL, Smith MA. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cell Mol Life Sci. 2005 Feb; 62(3):293-8.
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    Score: 0.037
  371. Zhu X, Perry G, Smith MA. Insulin signaling, diabetes mellitus and risk of Alzheimer disease. J Alzheimers Dis. 2005 Feb; 7(1):81-4.
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    Score: 0.037
  372. Marlatt MW, Webber KM, Moreira PI, Lee HG, Casadesus G, Honda K, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: one for all or all for one? Curr Med Chem. 2005; 12(10):1137-47.
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    Score: 0.037
  373. Zhu X, Lee HG, Casadesus G, Avila J, Drew K, Perry G, Smith MA. Oxidative imbalance in Alzheimer's disease. Mol Neurobiol. 2005; 31(1-3):205-17.
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    Score: 0.037
  374. Sayre LM, Moreira PI, Smith MA, Perry G. Metal ions and oxidative protein modification in neurological disease. Ann Ist Super Sanita. 2005; 41(2):143-64.
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    Score: 0.037
  375. Aliyev A, Chen SG, Seyidova D, Smith MA, Perry G, de la Torre J, Aliev G. Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease. J Neurol Sci. 2005 Mar 15; 229-230:285-92.
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    Score: 0.037
  376. Santa-Mar?a I, Smith MA, Perry G, Hern?ndez F, Avila J, Moreno FJ. Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease. Biochim Biophys Acta. 2005 Jun 10; 1740(3):472-80.
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    Score: 0.037
  377. Zhu X, Smith MA, Perry G, Aliev G. Mitochondrial failures in Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2004 Nov-Dec; 19(6):345-52.
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    Score: 0.037
  378. Zhu X, Webber KM, Casadesus G, Raina AK, Lee HG, Marlatt M, Hartzler A, Atwood CS, Perry G, Smith MA. Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities. Curr Drug Targets. 2004 Aug; 5(6):559-63.
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    Score: 0.036
  379. Casadesus G, Zhu X, Atwood CS, Webber KM, Perry G, Bowen RL, Smith MA. Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. Curr Drug Targets CNS Neurol Disord. 2004 Aug; 3(4):281-5.
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    Score: 0.036
  380. Castellani RJ, Honda K, Zhu X, Cash AD, Nunomura A, Perry G, Smith MA. Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease. Ageing Res Rev. 2004 Jul; 3(3):319-26.
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    Score: 0.036
  381. Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurol Res. 2004 Jul; 26(5):547-53.
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    Score: 0.036
  382. Dwyer BE, Raina AK, Perry G, Smith MA. Homocysteine and Alzheimer's disease: a modifiable risk? Free Radic Biol Med. 2004 Jun 01; 36(11):1471-5.
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    Score: 0.036
  383. Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. J Neurochem. 2004 Jun; 89(5):1233-40.
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    Score: 0.036
  384. Castellani RJ, Smith MA, Perry G, Friedland RP. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis. Neurobiol Aging. 2004 May-Jun; 25(5):599-602; discussion 603-4.
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    Score: 0.036
  385. Seyidova D, Aliyev A, Rzayev N, Obrenovich M, Lamb BT, Smith MA, de la Torre JC, Perry G, Aliev G. The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease. In Vivo. 2004 May-Jun; 18(3):325-33.
    View in: PubMed
    Score: 0.036
  386. Avila J, P?rez M, Lucas JJ, G?mez-Ramos A, Santa Mar?a I, Moreno F, Smith M, Perry G, Hern?ndez F. Assembly in vitro of tau protein and its implications in Alzheimer's disease. Curr Alzheimer Res. 2004 May; 1(2):97-101.
    View in: PubMed
    Score: 0.036
  387. Zhu X, Raina AK, Perry G, Smith MA. Alzheimer's disease: the two-hit hypothesis. Lancet Neurol. 2004 Apr; 3(4):219-26.
    View in: PubMed
    Score: 0.035
  388. Lee HG, Casadesus G, Zhu X, Joseph JA, Perry G, Smith MA. Perspectives on the amyloid-beta cascade hypothesis. J Alzheimers Dis. 2004 Apr; 6(2):137-45.
    View in: PubMed
    Score: 0.035
  389. Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. J Neurosci Res. 2004 Mar 01; 75(5):698-703.
    View in: PubMed
    Score: 0.035
  390. Honda K, Casadesus G, Petersen RB, Perry G, Smith MA. Oxidative stress and redox-active iron in Alzheimer's disease. Ann N Y Acad Sci. 2004 Mar; 1012:179-82.
    View in: PubMed
    Score: 0.035
  391. Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathol. 2004 Apr; 107(4):365-71.
    View in: PubMed
    Score: 0.035
  392. Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 2004 Jan 20; 43(2):560-8.
    View in: PubMed
    Score: 0.035
  393. Castellani RJ, Perry G, Smith MA. Prion disease and Alzheimer's disease: pathogenic overlap. Acta Neurobiol Exp (Wars). 2004; 64(1):11-7.
    View in: PubMed
    Score: 0.035
  394. G?mez-Ramos A, Smith MA, Perry G, Avila J. Tau phosphorylation and assembly. Acta Neurobiol Exp (Wars). 2004; 64(1):33-9.
    View in: PubMed
    Score: 0.035
  395. Marlatt M, Lee HG, Perry G, Smith MA, Zhu X. Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease. Acta Neurobiol Exp (Wars). 2004; 64(1):81-7.
    View in: PubMed
    Score: 0.035
  396. Lee HG, Zhu X, O'Neill MJ, Webber K, Casadesus G, Marlatt M, Raina AK, Perry G, Smith MA. The role of metabotropic glutamate receptors in Alzheimer's disease. Acta Neurobiol Exp (Wars). 2004; 64(1):89-98.
    View in: PubMed
    Score: 0.035
  397. Webber KM, Bowen R, Casadesus G, Perry G, Atwood CS, Smith MA. Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection. Acta Neurobiol Exp (Wars). 2004; 64(1):113-8.
    View in: PubMed
    Score: 0.035
  398. Zhu X, Raina AK, Lee HG, Chao M, Nunomura A, Tabaton M, Petersen RB, Perry G, Smith MA. Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways. Antioxid Redox Signal. 2003 Oct; 5(5):571-6.
    View in: PubMed
    Score: 0.034
  399. Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52.
    View in: PubMed
    Score: 0.034
  400. Zhu X, Sun Z, Lee HG, Siedlak SL, Perry G, Smith MA. Distribution, levels, and activation of MEK1 in Alzheimer's disease. J Neurochem. 2003 Jul; 86(1):136-42.
    View in: PubMed
    Score: 0.034
  401. Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, Herbert D, Cruz-Sanchez F, Chyan YJ, Smith MA, Perry G, Shoji M, Abe K, Leone A, Grundke-Ikbal I, Wilson GL, Ghiso J, Williams C, Refolo LM, Pappolla MA, Chain DG, Neria E. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem. 2003 Jun; 85(5):1101-8.
    View in: PubMed
    Score: 0.033
  402. Zhu X, Ogawa O, Wang Y, Perry G, Smith MA. JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease. J Neurochem. 2003 Apr; 85(1):87-93.
    View in: PubMed
    Score: 0.033
  403. Raina AK, Hochman A, Ickes H, Zhu X, Ogawa O, Cash AD, Shimohama S, Perry G, Smith MA. Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out? Prog Neuropsychopharmacol Biol Psychiatry. 2003 Apr; 27(2):251-4.
    View in: PubMed
    Score: 0.033
  404. Ogawa O, Lee HG, Zhu X, Raina A, Harris PL, Castellani RJ, Perry G, Smith MA. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2003 04; 2(2):105-10.
    View in: PubMed
    Score: 0.033
  405. Smith MA, Perry G, Atwood CS, Bowen RL. Estrogen replacement and risk of Alzheimer disease. JAMA. 2003 Mar 05; 289(9):1100; author reply 1101-2.
    View in: PubMed
    Score: 0.033
  406. Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathol. 2003 May; 105(5):524-8.
    View in: PubMed
    Score: 0.033
  407. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Tsuchiya D, Taniguchi T, Smith MA, Perry G, Shimohama S. Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis. Biochem Biophys Res Commun. 2003 Feb 14; 301(3):699-703.
    View in: PubMed
    Score: 0.033
  408. Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochem Biophys. 2003; 39(3):249-55.
    View in: PubMed
    Score: 0.032
  409. Atwood CS, Bishop GM, Perry G, Smith MA. Amyloid-beta: a vascular sealant that protects against hemorrhage? J Neurosci Res. 2002 Nov 01; 70(3):356.
    View in: PubMed
    Score: 0.032
  410. Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002 Nov 01; 70(3):357-60.
    View in: PubMed
    Score: 0.032
  411. Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. J Neurosci Res. 2002 Nov 01; 70(3):514-8.
    View in: PubMed
    Score: 0.032
  412. Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiol Aging. 2002 Nov-Dec; 23(6):1097-9.
    View in: PubMed
    Score: 0.032
  413. Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Ann N Y Acad Sci. 2002 Nov; 977:45-64.
    View in: PubMed
    Score: 0.032
  414. Kakimura J, Kitamura Y, Takata K, Tsuchiya D, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits. Ann N Y Acad Sci. 2002 Nov; 977:327-32.
    View in: PubMed
    Score: 0.032
  415. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible protective mechanisms of heme oxygenase-1 in the brain. Ann N Y Acad Sci. 2002 Nov; 977:501-6.
    View in: PubMed
    Score: 0.032
  416. Cash AD, Perry G, Ogawa O, Raina AK, Zhu X, Smith MA. Is Alzheimer's disease a mitochondrial disorder? Neuroscientist. 2002 Oct; 8(5):489-96.
    View in: PubMed
    Score: 0.032
  417. Cash AD, Perry G, Smith MA. Therapeutic potential in Alzheimer disease. Curr Med Chem. 2002 Sep; 9(17):1605-10.
    View in: PubMed
    Score: 0.032
  418. Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals. 2002 Sep-Oct; 11(5):270-81.
    View in: PubMed
    Score: 0.032
  419. Lee HG, Zhu X, Ghanbari HA, Ogawa O, Raina AK, O'Neill MJ, Perry G, Smith MA. Differential regulation of glutamate receptors in Alzheimer's disease. Neurosignals. 2002 Sep-Oct; 11(5):282-92.
    View in: PubMed
    Score: 0.032
  420. Smith MA, Atwood CS, Joseph JA, Perry G. Ill-fated amyloid-beta vaccine. J Neurosci Res. 2002 Aug 01; 69(3):285.
    View in: PubMed
    Score: 0.032
  421. Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radic Biol Med. 2002 Jul 15; 33(2):173-81.
    View in: PubMed
    Score: 0.031
  422. Rottkamp CA, Atwood CS, Joseph JA, Nunomura A, Perry G, Smith MA. The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides. 2002 Jul; 23(7):1333-41.
    View in: PubMed
    Score: 0.031
  423. Smith MA, Perry G, Pryor WA. Causes and consequences of oxidative stress in Alzheimer's disease. Free Radic Biol Med. 2002 Jun 01; 32(11):1049.
    View in: PubMed
    Score: 0.031
  424. Bishop GM, Robinson SR, Smith MA, Perry G, Atwood CS. Call for Elan to publish Alzheimer's trial details. Nature. 2002 Apr 18; 416(6882):677.
    View in: PubMed
    Score: 0.031
  425. Kakimura J, Kitamura Y, Takata K, Umeki M, Suzuki S, Shibagaki K, Taniguchi T, Nomura Y, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J. 2002 Apr; 16(6):601-3.
    View in: PubMed
    Score: 0.031
  426. Ogawa O, Perry G, Smith MA. The "Down's" side of mitochondria. Dev Cell. 2002 Mar; 2(3):255-6.
    View in: PubMed
    Score: 0.031
  427. Aliev G, Smith MA, Seyidov D, Neal ML, Lamb BT, Nunomura A, Gasimov EK, Vinters HV, Perry G, LaManna JC, Friedland RP. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol. 2002 Jan; 12(1):21-35.
    View in: PubMed
    Score: 0.030
  428. Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. CNS Drugs. 2002; 16(5):339-52.
    View in: PubMed
    Score: 0.030
  429. Bishop GM, Robinson SR, Liu Q, Perry G, Atwood CS, Smith MA. Iron: a pathological mediator of Alzheimer disease? Dev Neurosci. 2002; 24(2-3):184-7.
    View in: PubMed
    Score: 0.030
  430. Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mech Ageing Dev. 2001 Dec; 123(1):39-46.
    View in: PubMed
    Score: 0.030
  431. Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. J Neurochem. 2001 Oct; 79(2):311-8.
    View in: PubMed
    Score: 0.030
  432. Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug; 60(8):759-67.
    View in: PubMed
    Score: 0.029
  433. Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med. 2001 Jul 15; 31(2):175-80.
    View in: PubMed
    Score: 0.029
  434. Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem. 2001 Jun; 8(7):721-38.
    View in: PubMed
    Score: 0.029
  435. Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Duffy LK. Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease. Neuroreport. 2001 May 08; 12(6):1277-80.
    View in: PubMed
    Score: 0.029
  436. Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001 May 01; 21(9):3017-23.
    View in: PubMed
    Score: 0.029
  437. Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. 2001 Apr; 101(4):305-10.
    View in: PubMed
    Score: 0.029
  438. Perry G, Zhu X, Smith MA. Do neurons have a choice in death? Am J Pathol. 2001 Jan; 158(1):1-2.
    View in: PubMed
    Score: 0.028
  439. Joseph J, Shukitt-Hale B, Denisova NA, Martin A, Perry G, Smith MA. Copernicus revisited: amyloid beta in Alzheimer's disease. Neurobiol Aging. 2001 Jan-Feb; 22(1):131-46.
    View in: PubMed
    Score: 0.028
  440. Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem. 2001 Jan; 76(2):435-41.
    View in: PubMed
    Score: 0.028
  441. Mart?nez-Maldonado A, Ontiveros-Torres M?, Harrington CR, Montiel-Sosa JF, Prandiz RG, Bocanegra-L?pez P, Sorsby-Vargas AM, Bravo-Mu?oz M, Flor?n-Gardu?o B, Villanueva-Fierro I, Perry G, Garc?s-Ram?rez L, de la Cruz F, Mart?nez-Robles S, Pacheco-Herrero M, Luna-Mu?oz J. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration. J Alzheimers Dis. 2021; 79(4):1517-1531.
    View in: PubMed
    Score: 0.028
  442. Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol. 2000 Oct; 59(10):880-8.
    View in: PubMed
    Score: 0.028
  443. Takeda A, Smith MA, Avil? J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J Neurochem. 2000 Sep; 75(3):1234-41.
    View in: PubMed
    Score: 0.028
  444. Rottkamp CA, Nunomura A, Hirai K, Sayre LM, Perry G, Smith MA. Will antioxidants fulfill their expectations for the treatment of Alzheimer disease? Mech Ageing Dev. 2000 Jul 31; 116(2-3):169-79.
    View in: PubMed
    Score: 0.027
  445. Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. J Biol Chem. 2000 Jun 30; 275(26):19439-42.
    View in: PubMed
    Score: 0.027
  446. Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S. Activation of NADPH oxidase in Alzheimer's disease brains. Biochem Biophys Res Commun. 2000 Jun 24; 273(1):5-9.
    View in: PubMed
    Score: 0.027
  447. Shi J, Perry G, Smith MA, Friedland RP. Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease. Neurobiol Aging. 2000 Mar-Apr; 21(2):357-61.
    View in: PubMed
    Score: 0.027
  448. Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem. 2000 Jan; 74(1):270-9.
    View in: PubMed
    Score: 0.026
  449. Rottkamp CA, Nunomura A, Raina AK, Sayre LM, Perry G, Smith MA. Oxidative stress, antioxidants, and Alzheimer disease. Alzheimer Dis Assoc Disord. 2000; 14 Suppl 1:S62-6.
    View in: PubMed
    Score: 0.026
  450. Castellani RJ, Harris PL, Lecroisey A, Izadi-Pruneyre N, Wandersman C, Perry G, Smith MA. Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease. Antioxid Redox Signal. 2000; 2(1):137-42.
    View in: PubMed
    Score: 0.026
  451. Shi J, Perry G, Aliev G, Smith MA, Ashe KH, Friedland RP. Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model. Neuroreport. 1999 Oct 19; 10(15):3229-32.
    View in: PubMed
    Score: 0.026
  452. Castellani RJ, Perry G, Brenner DS, Smith MA. Alexander disease: Alzheimer disease of the developing brain? Alzheimer Dis Assoc Disord. 1999 Oct-Dec; 13(4):232-5.
    View in: PubMed
    Score: 0.026
  453. Raina AK, Takeda A, Nunomura A, Perry G, Smith MA. Genetic evidence for oxidative stress in Alzheimer's disease. Neuroreport. 1999 Apr 26; 10(6):1355-7.
    View in: PubMed
    Score: 0.025
  454. Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999 Mar 15; 19(6):1959-64.
    View in: PubMed
    Score: 0.025
  455. Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543.
    View in: PubMed
    Score: 0.025
  456. Nunomura A, Perry G, Hirai K, Aliev G, Takeda A, Chiba S, Smith MA. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann N Y Acad Sci. 1999; 893:362-4.
    View in: PubMed
    Score: 0.025
  457. Raina AK, Templeton DJ, Deak JC, Perry G, Smith MA. Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease. Redox Rep. 1999; 4(1-2):23-7.
    View in: PubMed
    Score: 0.025
  458. Hattori N, Kitagawa K, Higashida T, Yagyu K, Shimohama S, Wataya T, Perry G, Smith MA, Inagaki C. CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains. Neurosci Lett. 1998 Oct 02; 254(3):141-4.
    View in: PubMed
    Score: 0.024
  459. Guevara J, Espinosa B, Zenteno E, V?zguez L, Luna J, Perry G, Mena R. Altered glycosylation pattern of proteins in Alzheimer disease. J Neuropathol Exp Neurol. 1998 Oct; 57(10):905-14.
    View in: PubMed
    Score: 0.024
  460. Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA, Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol. 1998 Apr; 152(4):871-7.
    View in: PubMed
    Score: 0.023
  461. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):307-318.
    View in: PubMed
    Score: 0.023
  462. DeWitt DA, Perry G, Cohen M, Doller C, Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp Neurol. 1998 Feb; 149(2):329-40.
    View in: PubMed
    Score: 0.023
  463. Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5.
    View in: PubMed
    Score: 0.023
  464. Kitamura Y, Shimohama S, Kamoshima W, Ota T, Matsuoka Y, Nomura Y, Smith MA, Perry G, Whitehouse PJ, Taniguchi T. Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease. Brain Res. 1998 Jan 12; 780(2):260-9.
    View in: PubMed
    Score: 0.023
  465. M?nch G, Schinzel R, Loske C, Wong A, Durany N, Li JJ, Vlassara H, Smith MA, Perry G, Riederer P. Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts. J Neural Transm (Vienna). 1998; 105(4-5):439-61.
    View in: PubMed
    Score: 0.023
  466. Smith MA, Nagaraj RH, Perry G. Protocol for quantitative analysis of paired helical filament solubilization: a method applicable to insoluble amyloids and inclusion bodies. Brain Res Brain Res Protoc. 1997 Aug; 1(3):247-52.
    View in: PubMed
    Score: 0.022
  467. Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997 May; 68(5):2092-7.
    View in: PubMed
    Score: 0.022
  468. Tabaton M, Perry G, Smith M, Vitek M, Angelini G, Dapino D, Garibaldi S, Zaccheo D, Odetti P. Is amyloid beta-protein glycated in Alzheimer's disease? Neuroreport. 1997 Mar 03; 8(4):907-9.
    View in: PubMed
    Score: 0.022
  469. Xiao J, Perry G, Troncoso J, Monteiro MJ. alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease. J Neuropathol Exp Neurol. 1996 Sep; 55(9):954-63.
    View in: PubMed
    Score: 0.021
  470. Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016 10; 15(5):914-23.
    View in: PubMed
    Score: 0.021
  471. Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. Oxidative damage in Alzheimer's. Nature. 1996 Jul 11; 382(6587):120-1.
    View in: PubMed
    Score: 0.021
  472. Greenberg BD, Savage MJ, Howland DS, Ali SM, Siedlak SL, Perry G, Siman R, Scott RW. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol Aging. 1996 Mar-Apr; 17(2):153-71.
    View in: PubMed
    Score: 0.020
  473. Calder?n-Garcidue?as L, Reynoso-Robles R, Vargas-Mart?nez J, G?mez-Maqueo-Chew A, P?rez-Guill? B, Mukherjee PS, Torres-Jard?n R, Perry G, G?nzalez-Maciel A. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease. Environ Res. 2016 Apr; 146:404-17.
    View in: PubMed
    Score: 0.020
  474. Giaccone G, Pedrotti B, Migheli A, Verga L, Perez J, Racagni G, Smith MA, Perry G, De Gioia L, Selvaggini C, Salmona M, Ghiso J, Frangione B, Islam K, Bugiani O, Tagliavini F. beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. Am J Pathol. 1996 Jan; 148(1):79-87.
    View in: PubMed
    Score: 0.020
  475. Shimohama S, Fujimoto S, Chachin M, Taniguchi T, Perry G, Whitehouse PJ, Kimura J. Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease. Brain Res. 1995 Nov 13; 699(1):125-9.
    View in: PubMed
    Score: 0.020
  476. Castellani R, Smith MA, Richey PL, Kalaria R, Gambetti P, Perry G. Evidence for oxidative stress in Pick disease and corticobasal degeneration. Brain Res. 1995 Oct 23; 696(1-2):268-71.
    View in: PubMed
    Score: 0.020
  477. Premkumar DR, Smith MA, Richey PL, Petersen RB, Castellani R, Kutty RK, Wiggert B, Perry G, Kalaria RN. Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease. J Neurochem. 1995 Sep; 65(3):1399-402.
    View in: PubMed
    Score: 0.020
  478. Yan SD, Yan SF, Chen X, Fu J, Chen M, Kuppusamy P, Smith MA, Perry G, Godman GC, Nawroth P, et al. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat Med. 1995 Jul; 1(7):693-9.
    View in: PubMed
    Score: 0.019
  479. Shimohama S, Fujimoto S, Matsushima H, Takenawa T, Taniguchi T, Perry G, Whitehouse PJ, Kimura J. Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease. J Neurochem. 1995 Jun; 64(6):2629-34.
    View in: PubMed
    Score: 0.019
  480. Shimohama S, Perry G, Richey P, Praprotnik D, Takenawa T, Fukami K, Whitehouse PJ, Kimura J. Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles. Brain Res. 1995 Jan 16; 669(2):217-24.
    View in: PubMed
    Score: 0.019
  481. Canning DR, McKeon RJ, DeWitt DA, Perry G, Wujek JR, Frederickson RC, Silver J. beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth. Exp Neurol. 1993 Dec; 124(2):289-98.
    View in: PubMed
    Score: 0.017
  482. Shimohama S, Fujimoto S, Tresser N, Richey P, Perry G, Whitehouse PJ, Homma Y, Takenawa T, Taniguchi T, Suenaga T, et al. Aberrant phosphoinositide metabolism in Alzheimer's disease. Ann N Y Acad Sci. 1993 Sep 24; 695:46-9.
    View in: PubMed
    Score: 0.017
  483. Ciss? S, Perry G, Lacoste-Royal G, Cabana T, Gauvreau D. Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains. Acta Neuropathol. 1993; 85(3):233-40.
    View in: PubMed
    Score: 0.016
  484. Greco SJ, Hamzelou A, Johnston JM, Richardson S, Smith MA, Perry G, Ashford JW, Tezapsidis N. Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest. Curr Alzheimer Res. 2012 Dec; 9(10):1168-73.
    View in: PubMed
    Score: 0.016
  485. Tabaton M, Cammarata S, Mandybur T, Richey P, Kawai M, Perry G, Gambetti P. Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities. Brain Res. 1992 Oct 16; 593(2):299-303.
    View in: PubMed
    Score: 0.016
  486. Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):81-5.
    View in: PubMed
    Score: 0.015
  487. Wise-Scira O, Xu L, Kitahara T, Perry G, Coskuner O. Amyloid-? peptide structure in aqueous solution varies with fragment size. J Chem Phys. 2011 Nov 28; 135(20):205101.
    View in: PubMed
    Score: 0.015
  488. Gheuens J, Cras P, Perry G, Boons J, Ceuterick-de Groote C, L?bke U, Mercken M, Tabaton M, Gambetti PL, Vandermeeren M, et al. Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases. Brain Res. 1991 Aug 30; 558(1):43-52.
    View in: PubMed
    Score: 0.015
  489. Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol. 2011 Jul; 70(7):578-87.
    View in: PubMed
    Score: 0.015
  490. Valdez CM, Phelix CF, Smith MA, Perry G, Santamaria F. Modeling cholesterol metabolism by gene expression profiling in the hippocampus. Mol Biosyst. 2011 Jun; 7(6):1891-901.
    View in: PubMed
    Score: 0.014
  491. Tabaton M, Cammarata S, Mancardi G, Manetto V, Autilio-Gambetti L, Perry G, Gambetti P. Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2098-102.
    View in: PubMed
    Score: 0.014
  492. Tabaton M, Cammarata S, Mancardi GL, Cordone G, Perry G, Loeb C. Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease. Neurology. 1991 Mar; 41(3):391-4.
    View in: PubMed
    Score: 0.014
  493. Murphy GM, Eng LF, Ellis WG, Perry G, Meissner LC, Tinklenberg JR. Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease. Brain Res. 1990 Dec 24; 537(1-2):102-8.
    View in: PubMed
    Score: 0.014
  494. Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation. Neurobiol Aging. 2012 Jan; 33(1):196.e13-27.
    View in: PubMed
    Score: 0.014
  495. Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. J Neurosci Methods. 2010 Jul 15; 190(2):244-7.
    View in: PubMed
    Score: 0.014
  496. Tabaton M, Mandybur TI, Perry G, Onorato M, Autilio-Gambetti L, Gambetti P. The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition. Ann Neurol. 1989 Dec; 26(6):771-8.
    View in: PubMed
    Score: 0.013
  497. Palmert MR, Siedlak SL, Podlisny MB, Greenberg B, Shelton ER, Chan HW, Usiak M, Selkoe DJ, Perry G, Younkin SG. Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein. Biochem Biophys Res Commun. 1989 Nov 30; 165(1):182-8.
    View in: PubMed
    Score: 0.013
  498. Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta. 2010 Jan; 1802(1):212-20.
    View in: PubMed
    Score: 0.013
  499. Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta. 2010 Jan; 1802(1):135-42.
    View in: PubMed
    Score: 0.013
  500. Tabaton M, Cammarata S, Manetto V, Perry G, Mancardi G. Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease. Neurosci Lett. 1989 Sep 11; 103(3):259-62.
    View in: PubMed
    Score: 0.013
  501. Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L. Signaling effect of amyloid-beta(42) on the processing of AbetaPP. Exp Neurol. 2010 Jan; 221(1):18-25.
    View in: PubMed
    Score: 0.013
  502. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66.
    View in: PubMed
    Score: 0.013
  503. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56.
    View in: PubMed
    Score: 0.012
  504. Whitehouse PJ, Gambetti P, Harik SI, Kalaria RN, Perry G, Younkin SI, Tabaton M, Unnerstall JR. Neurochemistry of dementia: establishing the links. Prog Clin Biol Res. 1989; 317:131-42.
    View in: PubMed
    Score: 0.012
  505. Autilio-Gambetti L, Morandi A, Kovacs DM, Tabaton M, Schaetzle B, Hauer C, Groger RK, Tykocinski ML, Perry G, Greenberg BD, et al. Amyloid precursor protein in cell cultures: a 130 kDa polypeptide. Prog Clin Biol Res. 1989; 317:985-90.
    View in: PubMed
    Score: 0.012
  506. Autilio-Gambetti L, Morandi A, Tabaton M, Schaetzle B, Kovacs D, Perry G, Sharma S, Cornette J, Greenberg B, Gambetti P. The amyloid percursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types. FEBS Lett. 1988 Dec 05; 241(1-2):94-8.
    View in: PubMed
    Score: 0.012
  507. Tabaton M, Whitehouse PJ, Perry G, Davies P, Autilio-Gambetti L, Gambetti P. Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy. Ann Neurol. 1988 Sep; 24(3):407-13.
    View in: PubMed
    Score: 0.012
  508. Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. J Alzheimers Dis. 2008 Aug; 14(4):377-83.
    View in: PubMed
    Score: 0.012
  509. Manetto V, Perry G, Tabaton M, Mulvihill P, Fried VA, Smith HT, Gambetti P, Autilio-Gambetti L. Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4501-5.
    View in: PubMed
    Score: 0.012
  510. Tabaton M, Perry G, Autilio-Gambetti L, Manetto V, Gambetti P. Influence of neuronal location on antigenic properties of neurofibrillary tangles. Ann Neurol. 1988 Jun; 23(6):604-10.
    View in: PubMed
    Score: 0.012
  511. Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. J Biol Chem. 2008 Aug 15; 283(33):22550-6.
    View in: PubMed
    Score: 0.012
  512. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol. 2008 Jan; 21(1):172-88.
    View in: PubMed
    Score: 0.011
  513. Galloway PG, Perry G, Kosik KS, Gambetti P. Hirano bodies contain tau protein. Brain Res. 1987 Feb 17; 403(2):337-40.
    View in: PubMed
    Score: 0.011
  514. Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94.
    View in: PubMed
    Score: 0.010
  515. Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci. 2004 Jun; 1019:1-4.
    View in: PubMed
    Score: 0.009
  516. Gambetti P, Autilio-Gambetti L, Perry G, Shecket G, Crane RC. Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions. Lab Invest. 1983 Oct; 49(4):430-5.
    View in: PubMed
    Score: 0.009
  517. Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN. Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev. 2003 Sep; 43(1):1-16.
    View in: PubMed
    Score: 0.008
  518. Shi J, Perry G, Berridge MS, Aliev G, Siedlak SL, Smith MA, LaManna JC, Friedland RP. Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med. 2002 Aug; 43(8):1044-51.
    View in: PubMed
    Score: 0.008
  519. Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology. 2002 Feb 26; 58(4):589-92.
    View in: PubMed
    Score: 0.008
  520. Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". J Neurochem. 2001 Jul; 78(1):121-8.
    View in: PubMed
    Score: 0.007
  521. Clapp-Lilly KL, Smith MA, Perry G, Duffy LK. Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices. Chem Biol Interact. 2001 Mar 14; 134(1):101-7.
    View in: PubMed
    Score: 0.007
  522. Sayre LM, Perry G, Atwood CS, Smith MA. The role of metals in neurodegenerative diseases. Cell Mol Biol (Noisy-le-grand). 2000 Jun; 46(4):731-41.
    View in: PubMed
    Score: 0.007
  523. Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, Menini S, Traverso N, Zaccheo D, Siedlak S, Perry G, Smith MA, Tabaton M. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol. 2000 May; 59(5):393-7.
    View in: PubMed
    Score: 0.007
  524. Takeda A, Perry G, Abraham NG, Dwyer BE, Kutty RK, Laitinen JT, Petersen RB, Smith MA. Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem. 2000 Feb 25; 275(8):5395-9.
    View in: PubMed
    Score: 0.007
  525. Raina AK, Perry G, Nunomura A, Sayre LM, Smith MA. Histochemical and immunocytochemical approaches to the study of oxidative stress. Clin Chem Lab Med. 2000 Feb; 38(2):93-7.
    View in: PubMed
    Score: 0.007
  526. Chen X, Eswaran D, Smith MA, Perry G, Anderson VE. Universal isolation of cross-linked peptides: application to neurofibrillary tangles. Bioconjug Chem. 1999 Jan-Feb; 10(1):112-8.
    View in: PubMed
    Score: 0.006
  527. Sayre LM, Perry G, Smith MA. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol. 1999; 309:133-52.
    View in: PubMed
    Score: 0.006
  528. Ali SM, Siedlak SL, Gonzalez-DeWhitt PA, Altman RA, Glendening JM, Lowery DE, Savage MJ, Polites HG, Perry G, Greenberg BD. Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice. Neurobiol Aging. 1996 Mar-Apr; 17(2):223-34.
    View in: PubMed
    Score: 0.005
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