Renato J. Aguilera to Antineoplastic Agents
This is a "connection" page, showing publications Renato J. Aguilera has written about Antineoplastic Agents.
Connection Strength
4.604
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Borrego EA, Guerena CD, Schiaffino Bustamante AY, Gutierrez DA, Valenzuela CA, Betancourt AP, Varela-Ramirez A, Aguilera RJ. A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells. Cells. 2024 Jul 20; 13(14).
Score: 0.570
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Swain RM, Sanchez A, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Thiophene derivative inflicts cytotoxicity via an intrinsic apoptotic pathway on human acute lymphoblastic leukemia cells. PLoS One. 2023; 18(12):e0295441.
Score: 0.548
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Swain RM, Contreras L, Varela-Ramirez A, Hossain M, Das U, Valenzuela CA, Penichet ML, Dimmock JR, Aguilera RJ. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. Invest New Drugs. 2022 Oct; 40(5):905-921.
Score: 0.495
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Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ. A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation. Cell Biol Toxicol. 2019 12; 35(6):503-519.
Score: 0.393
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Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis. PLoS One. 2018; 13(11):e0206467.
Score: 0.384
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Robles-Escajeda E, Das U, Ortega NM, Parra K, Francia G, Dimmock JR, Varela-Ramirez A, Aguilera RJ. A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cells. Cell Oncol (Dordr). 2016 Jun; 39(3):265-77.
Score: 0.319
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Varela-Ramirez A, Costanzo M, Carrasco YP, Pannell KH, Aguilera RJ. Cytotoxic effects of two organotin compounds and their mode of inflicting cell death on four mammalian cancer cells. Cell Biol Toxicol. 2011 Jun; 27(3):159-68.
Score: 0.220
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Bhatt HN, Diwan R, Borrego EA, P?rez CAM, Varela-Ramirez A, Kumar R, Aguilera RJ, Nurunnabi M. A photothermal driven chemotherapy for the treatment of metastatic melanoma. J Control Release. 2023 09; 361:314-333.
Score: 0.134
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Jain PM, Gutierrez DA, Kumar S, Aguilera RJ, Karki SS. Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis. Chem Biodivers. 2023 Sep; 20(9):e202300843.
Score: 0.134
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Chhikara A, Roayapalley PK, Sakagami H, Amano S, Satoh K, Uesawa Y, Das U, Das S, Borrego EA, Guerena CD, Hernandez CR, Aguilera RJ, Dimmock JR. Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity. Molecules. 2022 Oct 09; 27(19).
Score: 0.126
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Huda MN, Deaguero IG, Borrego EA, Kumar R, Islam T, Afrin H, Varela-Ramirez A, Aguilera RJ, Tanner EEL, Nurunnabi M. Ionic liquid-mediated delivery of a BCL-2 inhibitor for topical treatment of skin melanoma. J Control Release. 2022 09; 349:783-795.
Score: 0.124
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Roayapalley PK, Dimmock JR, Contreras L, Balderrama KS, Aguilera RJ, Sakagami H, Amano S, Sharma RK, Das U. Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts. Molecules. 2021 Nov 25; 26(23).
Score: 0.119
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Contreras L, Medina S, Schiaffino Bustamante AY, Borrego EA, Valenzuela CA, Das U, Karki SS, Dimmock JR, Aguilera RJ. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep. 2022 Feb; 74(1):159-174.
Score: 0.117
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Choodamani B, Cano Hernandez KG, Kumar S, Tony AM, Schiaffino Bustamante AY, Aguilera RJ, Schols D, Gopi Mohan C, Karki SS. Synthesis, Molecular Docking and Preliminary Antileukemic Activity of 4-Methoxybenzyl Derivatives Bearing Imidazo[2,1-b][1,3,4]thiadiazole. Chem Biodivers. 2021 Feb; 18(2):e2000800.
Score: 0.112
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Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15; 202:112603.
Score: 0.108
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Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Guti?rrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Ch?vez-B?ez I, Pulgar R, Urra FA, Varela-Ram?rez A, Araya-Maturana R. An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells. Bioorg Chem. 2020 07; 100:103935.
Score: 0.107
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Iglesias-Figueroa BF, Siqueiros-Cend?n TS, Gutierrez DA, Aguilera RJ, Espinoza-S?nchez EA, Ar?valo-Gallegos S, Varela-Ramirez A, Rasc?n-Cruz Q. Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells. Apoptosis. 2019 08; 24(7-8):562-577.
Score: 0.101
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Nunes LM, Robles-Escajeda E, Santiago-Vazquez Y, Ortega NM, Lema C, Muro A, Almodovar G, Das U, Das S, Dimmock JR, Aguilera RJ, Varela-Ramirez A. The gender of cell lines matters when screening for novel anti-cancer drugs. AAPS J. 2014 Jul; 16(4):872-4.
Score: 0.071
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Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ram?rez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity. Eur J Med Chem. 2014 Apr 22; 77:315-22.
Score: 0.069
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Pedroza DA, De Leon F, Varela-Ramirez A, Lema C, Aguilera RJ, Mito S. The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells. Bioorg Med Chem. 2014 Jan 15; 22(2):842-7.
Score: 0.068
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Gonz?lez-Pantoja JF, Stern M, Jarzecki AA, Royo E, Robles-Escajeda E, Varela-Ram?rez A, Aguilera RJ, Contel M. Titanocene-phosphine derivatives as precursors to cytotoxic heterometallic TiAu2 and TiM (M = Pd, Pt) compounds. Studies of their interactions with DNA. Inorg Chem. 2011 Nov 07; 50(21):11099-110.
Score: 0.059
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Das S, Das U, Varela-Ram?rez A, Lema C, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: a novel class of potent cytotoxins. ChemMedChem. 2011 Oct 04; 6(10):1892-9.
Score: 0.058
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Mart?nez A, Rajapakse CS, S?nchez-Delgado RA, Varela-Ramirez A, Lema C, Aguilera RJ. Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells. J Inorg Biochem. 2010 Sep; 104(9):967-77.
Score: 0.053
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Shaik N, Mart?nez A, Augustin I, Giovinazzo H, Varela-Ram?rez A, Sana? M, Aguilera RJ, Contel M. Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets. Inorg Chem. 2009 Feb 16; 48(4):1577-87.
Score: 0.049
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Montoya J, Varela-Ramirez A, Shanmugasundram M, Martinez LE, Primm TP, Aguilera RJ. Tandem screening of toxic compounds on GFP-labeled bacteria and cancer cells in microtiter plates. Biochem Biophys Res Commun. 2005 Sep 23; 335(2):367-72.
Score: 0.039
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Tilekar K, Hess JD, Upadhyay N, Bianco AL, Schweipert M, Laghezza A, Loiodice F, Meyer-Almes FJ, Aguilera RJ, Lavecchia A, C S R. Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPAR? and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. J Med Chem. 2021 05 27; 64(10):6949-6971.
Score: 0.029