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Connection

Eunsook Lee to Humans

This is a "connection" page, showing publications Eunsook Lee has written about Humans.
Connection Strength

0.616
  1. Pajarillo E, Kim S, Digman A, Dutton M, Son DS, Aschner M, Lee E. The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction. J Biol Chem. 2023 07; 299(7):104879.
    View in: PubMed
    Score: 0.042
  2. Kim S, Pajarillo E, Nyarko-Danquah I, Aschner M, Lee E. Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants. Cells. 2023 02 15; 12(4).
    View in: PubMed
    Score: 0.041
  3. Pajarillo E, Demayo M, Digman A, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice. Glia. 2022 10; 70(10):1886-1901.
    View in: PubMed
    Score: 0.039
  4. Rizor A, Pajarillo E, Son DS, Aschner M, Lee E. Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes. Toxicol Lett. 2022 Feb 01; 355:41-46.
    View in: PubMed
    Score: 0.038
  5. Pajarillo E, Digman A, Nyarko-Danquah I, Son DS, Soliman KFA, Aschner M, Lee E. Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity. J Biol Chem. 2021 12; 297(6):101372.
    View in: PubMed
    Score: 0.038
  6. Rizor A, Pajarillo E, Nyarko-Danquah I, Digman A, Mooneyham L, Son DS, Aschner M, Lee E. Manganese-induced reactive oxygen species activate I?B kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro. Neurotoxicology. 2021 09; 86:94-103.
    View in: PubMed
    Score: 0.037
  7. Nyarko-Danquah I, Pajarillo E, Digman A, Soliman KFA, Aschner M, Lee E. Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms. Molecules. 2020 Dec 12; 25(24).
    View in: PubMed
    Score: 0.036
  8. Pajarillo E, Rizor A, Lee J, Aschner M, Lee E. The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics. Neuropharmacology. 2019 12 15; 161:107559.
    View in: PubMed
    Score: 0.032
  9. Kim J, Pajarillo E, Rizor A, Son DS, Lee J, Aschner M, Lee E. LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia. PLoS One. 2019; 14(1):e0210248.
    View in: PubMed
    Score: 0.031
  10. Pajarillo E, Rizor A, Lee J, Aschner M, Lee E. The role of posttranslational modifications of a-synuclein and LRRK2 in Parkinson's disease: Potential contributions of environmental factors. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):1992-2000.
    View in: PubMed
    Score: 0.031
  11. Karki P, Hong P, Johnson J, Pajarillo E, Son DS, Aschner M, Lee EY. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-?B Pathways. Mol Neurobiol. 2018 Jun; 55(6):5031-5046.
    View in: PubMed
    Score: 0.028
  12. Lee E, Karki P, Johnson J, Hong P, Aschner M. Manganese Control of Glutamate Transporters' Gene Expression. Adv Neurobiol. 2017; 16:1-12.
    View in: PubMed
    Score: 0.027
  13. Karki P, Johnson J, Son DS, Aschner M, Lee E. Transcriptional Regulation of Human Transforming Growth Factor-a in Astrocytes. Mol Neurobiol. 2017 03; 54(2):964-976.
    View in: PubMed
    Score: 0.025
  14. Karki P, Smith K, Johnson J, Aschner M, Lee E. Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity. Neurochem Int. 2015 Sep; 88:53-9.
    View in: PubMed
    Score: 0.023
  15. Karki P, Smith K, Johnson J, Aschner M, Lee EY. Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicity. Neurochem Res. 2015 Feb; 40(2):380-8.
    View in: PubMed
    Score: 0.023
  16. Karki P, Smith K, Johnson J, Lee E. Astrocyte-derived growth factors and estrogen neuroprotection: role of transforming growth factor-a in estrogen-induced upregulation of glutamate transporters in astrocytes. Mol Cell Endocrinol. 2014 May 25; 389(1-2):58-64.
    View in: PubMed
    Score: 0.022
  17. Karki P, Webb A, Smith K, Lee K, Son DS, Aschner M, Lee E. cAMP response element-binding protein (CREB) and nuclear factor ?B mediate the tamoxifen-induced up-regulation of glutamate transporter 1 (GLT-1) in rat astrocytes. J Biol Chem. 2013 Oct 04; 288(40):28975-86.
    View in: PubMed
    Score: 0.021
  18. Aschner M, Skalny AV, Paoliello MMB, Tinkova MN, Martins AC, Santamaria A, Lee E, Rocha JBT, Farsky SHP, Tinkov AA. Retinal toxicity of heavy metals and its involvement in retinal pathology. Food Chem Toxicol. 2024 Jun; 188:114685.
    View in: PubMed
    Score: 0.011
  19. Tinkov AA, Martins AC, Avila DS, Gritsenko VA, Skalny AV, Santamaria A, Lee E, Bowman AB, Aschner M. Gut Microbiota as a Potential Player in Mn-Induced Neurotoxicity. Biomolecules. 2021 08 31; 11(9).
    View in: PubMed
    Score: 0.009
  20. Tinkov AA, Paoliello MMB, Mazilina AN, Skalny AV, Martins AC, Voskresenskaya ON, Aaseth J, Santamaria A, Notova SV, Tsatsakis A, Lee E, Bowman AB, Aschner M. Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update. Int J Mol Sci. 2021 Apr 28; 22(9).
    View in: PubMed
    Score: 0.009
  21. Martins AC, Ruella Oliveira S, Barbosa F, Tinkov AA, V Skalny A, Santamar?a A, Lee E, Bowman AB, Aschner M. Evaluating the risk of manganese-induced neurotoxicity of parenteral nutrition: review of the current literature. Expert Opin Drug Metab Toxicol. 2021 May; 17(5):581-593.
    View in: PubMed
    Score: 0.009
  22. Martins AC, Gubert P, Villas Boas GR, Meirelles Paes M, Santamar?a A, Lee E, Tinkov AA, Bowman AB, Aschner M. Manganese-induced neurodegenerative diseases and possible therapeutic approaches. Expert Rev Neurother. 2020 11; 20(11):1109-1121.
    View in: PubMed
    Score: 0.009
  23. Ke T, Sidoryk-Wegrzynowicz M, Pajarillo E, Rizor A, Soares FAA, Lee E, Aschner M. Role of Astrocytes in Manganese Neurotoxicity Revisited. Neurochem Res. 2019 Nov; 44(11):2449-2459.
    View in: PubMed
    Score: 0.008
  24. Martins AC, Morcillo P, Ijomone OM, Venkataramani V, Harrison FE, Lee E, Bowman AB, Aschner M. New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease. Int J Environ Res Public Health. 2019 09 22; 16(19).
    View in: PubMed
    Score: 0.008
  25. Chen P, Chakraborty S, Mukhopadhyay S, Lee E, Paoliello MM, Bowman AB, Aschner M. Manganese homeostasis in the nervous system. J Neurochem. 2015 Aug; 134(4):601-10.
    View in: PubMed
    Score: 0.006
  26. Son DS, Kabir SM, Dong YL, Lee E, Adunyah SE. Inhibitory effect of tumor suppressor p53 on proinflammatory chemokine expression in ovarian cancer cells by reducing proteasomal degradation of I?B. PLoS One. 2012; 7(12):e51116.
    View in: PubMed
    Score: 0.005
  27. Sidoryk-Wegrzynowicz M, Wegrzynowicz M, Lee E, Bowman AB, Aschner M. Role of astrocytes in brain function and disease. Toxicol Pathol. 2011 Jan; 39(1):115-23.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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