"Mucin 5AC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gel-forming mucin that is primarily found on the surface of gastric epithelium and in the RESPIRATORY TRACT. Mucin 5AC was originally identified as two distinct proteins, however a single gene encodes the protein which gives rise to the mucin 5A and mucin 5C variants.
| Descriptor ID |
D055271
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| MeSH Number(s) |
D12.776.395.560.631.100.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucin 5AC".
Below are MeSH descriptors whose meaning is more specific than "Mucin 5AC".
This graph shows the total number of publications written about "Mucin 5AC" by people in this website by year, and whether "Mucin 5AC" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mucin 5AC" by people in Profiles.
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Chand HS, Harris JF, Tesfaigzi Y. IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells. Sci Rep. 2018 01 11; 8(1):436.
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Chand HS, Mebratu YA, Kuehl PJ, Tesfaigzi Y. Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. J Allergy Clin Immunol. 2017 11; 140(5):1456-1459.e9.
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Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA. Protective role for club cell secretory protein-16 (CC16) in the development of COPD. Eur Respir J. 2015 Jun; 45(6):1544-56.
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Chand HS, Woldegiorgis Z, Schwalm K, McDonald J, Tesfaigzi Y. Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):784-91.
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Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Pe?a-Philippides JC, Koga T, Razani-Boroujerdi S, Hutt J, Campen M, Kim KC, Tesfaigzi Y, Sopori ML. Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. J Immunol. 2008 Jun 01; 180(11):7655-63.
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Schwalm K, Stevens JF, Jiang Z, Schuyler MR, Schrader R, Randell SH, Green FH, Tesfaigzi Y. Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1102-9.