Interleukin-1 Receptor Accessory Protein
"Interleukin-1 Receptor Accessory Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.
Descriptor ID |
D053577
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MeSH Number(s) |
D12.776.543.750.705.852.420.300.249
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1 Receptor Accessory Protein".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1 Receptor Accessory Protein".
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