Polyunsaturated Alkamides
"Polyunsaturated Alkamides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Amides composed of unsaturated aliphatic FATTY ACIDS linked with AMINES by an amide bond. They are most prominent in ASTERACEAE; PIPERACEAE; and RUTACEAE; and also found in ARISTOLOCHIACEAE; BRASSICACEAE; CONVOLVULACEAE; EUPHORBIACEAE; MENISPERMACEAE; POACEAE; and SOLANACEAE. They are recognized by their pungent taste and for causing numbing and salivation.
| Descriptor ID |
D053284
|
| MeSH Number(s) |
D02.065.160 D02.455.326.271.060 D02.455.326.397.675
|
| Concept/Terms |
Polyunsaturated Alkamides- Polyunsaturated Alkamides
- Alkamides, Polyunsaturated
- Alkylamides, Polyunsaturated
- Polyunsaturated Alkylamides
|
Below are MeSH descriptors whose meaning is more general than "Polyunsaturated Alkamides".
Below are MeSH descriptors whose meaning is more specific than "Polyunsaturated Alkamides".
This graph shows the total number of publications written about "Polyunsaturated Alkamides" by people in this website by year, and whether "Polyunsaturated Alkamides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polyunsaturated Alkamides" by people in Profiles.
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Jagla CAD, Scott CE, Tang Y, Qiao C, Mateo-Semidey GE, Yudowski GA, Lu D, Kendall DA. Pyrimidinyl Biphenylureas Act as Allosteric Modulators to Activate Cannabinoid Receptor 1 and Initiate ?-Arrestin-Dependent Responses. Mol Pharmacol. 2019 01; 95(1):1-10.
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Xu C, Hermes DJ, Nwanguma B, Jacobs IR, Mackie K, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska B, Fitting S. Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. Mol Cell Neurosci. 2017 09; 83:92-102.
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Wang ZJ, Sun L, Heinbockel T. Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. J Neurosci. 2012 Jun 20; 32(25):8475-9.
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Carney ST, Lloyd ML, MacKinnon SE, Newton DC, Jones JD, Howlett AC, Norford DC. Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. J Neuroimmune Pharmacol. 2009 Sep; 4(3):338-49.
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Balas L, Durand T, Saha S, Johnson I, Mukhopadhyay S. Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. J Med Chem. 2009 Feb 26; 52(4):1005-17.
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Njie YF, Qiao Z, Xiao Z, Wang W, Song ZH. N-arachidonylethanolamide-induced increase in aqueous humor outflow facility. Invest Ophthalmol Vis Sci. 2008 Oct; 49(10):4528-34.
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Mukhopadhyay S, Tulis DA. Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. Cardiovasc Hematol Agents Med Chem. 2007 Oct; 5(4):311-8.
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Shivachar AC. Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes. Biochem Pharmacol. 2007 Jun 15; 73(12):2004-11.
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McCollum L, Howlett AC, Mukhopadhyay S. Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. J Pharmacol Exp Ther. 2007 Jun; 321(3):930-7.
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Awumey EM, Howlett AC, Diz DI. Is there a role for anandamide in cardiovascular regulation? Insights from studies of endocannabinoid metabolism. Am J Physiol Heart Circ Physiol. 2005 Aug; 289(2):H520-1.