Methylmalonate-Semialdehyde Dehydrogenase (Acylating)
"Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the VALINE; LEUCINE; and ISOLEUCINE catabolic pathways by catalyzing the oxidation of 2-methyl-3-oxopropanate to propanoyl-CoA using NAD+ as a coenzyme. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated BETA-ALANINE and 3-hydropropionic acid.
Descriptor ID |
D050646
|
MeSH Number(s) |
D08.811.682.657.163.827
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Concept/Terms |
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