Serotonin Plasma Membrane Transport Proteins

"Serotonin Plasma Membrane Transport Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.

Descriptor ID	D050486
MeSH Number(s)	D12.776.157.530.450.625.311 D12.776.157.530.562.374.875 D12.776.157.530.937.624 D12.776.543.585.450.625.374 D12.776.543.585.562.374.875 D12.776.543.585.937.747
Concept/Terms	Serotonin Plasma Membrane Transport Proteins Serotonin Plasma Membrane Transport Proteins Serotonin Plasma Membrane Transporter Proteins Neurotransmitter Transporters, Serotonin-Specific Neurotransmitter Transporters, Serotonin Specific Serotonin-Specific Neurotransmitter Transporters 5-Hydroxytryptamine Plasma Membrane Transport Protein 5 Hydroxytryptamine Plasma Membrane Transport Protein Neurotransmitter Transport Proteins, Serotonin-Specific Neurotransmitter Transport Proteins, Serotonin Specific Serotonin Transporter SERT Proteins Solute Carrier Family 6, Member 4 Protein Solute Carrier Family 6, Member 4 Protein Sodium-Dependent Serotonin Transporter Serotonin Transporter, Sodium-Dependent Sodium Dependent Serotonin Transporter Transporter, Sodium-Dependent Serotonin 5HT Transporter SLC6A4 Protein Serotonectin Serotonectin Platelet Serotonin Transporter Serotonin Transporter, Platelet Serotonin Transporter, Platelets Platelets Serotonin Transporter

Below are MeSH descriptors whose meaning is more general than "Serotonin Plasma Membrane Transport Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Symporters [D12.776.157.530.450.625]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.450.625.311]
Neurotransmitter Transport Proteins [D12.776.157.530.562]
Plasma Membrane Neurotransmitter Transport Proteins [D12.776.157.530.562.374]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.562.374.875]
Solute Carrier Proteins [D12.776.157.530.937]
Serotonin Plasma Membrane Transport Proteins [D12.776.157.530.937.624]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Ion Pumps [D12.776.543.585.450]
Symporters [D12.776.543.585.450.625]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.450.625.374]
Neurotransmitter Transport Proteins [D12.776.543.585.562]
Plasma Membrane Neurotransmitter Transport Proteins [D12.776.543.585.562.374]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.562.374.875]
Solute Carrier Proteins [D12.776.543.585.937]
Serotonin Plasma Membrane Transport Proteins [D12.776.543.585.937.747]

Below are MeSH descriptors whose meaning is related to "Serotonin Plasma Membrane Transport Proteins".

Below are MeSH descriptors whose meaning is more specific than "Serotonin Plasma Membrane Transport Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Serotonin Plasma Membrane Transport Proteins" by people in this website by year, and whether "Serotonin Plasma Membrane Transport Proteins" was a major or minor topic of these publications.

Bar chart showing 11 publications over 7 distinct years, with a maximum of 2 publications in 2012 and 2015 and 2016 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	1	1
2009	1	0	1
2011	1	0	1
2012	2	0	2
2015	1	1	2
2016	1	1	2
2017	1	1	2

Below are the most recent publications written about "Serotonin Plasma Membrane Transport Proteins" by people in Profiles.

Trucco EM, Villafuerte S, Hussong A, Burmeister M, Zucker RA. Biological underpinnings of an internalizing pathway to alcohol, cigarette, and marijuana use. J Abnorm Psychol. 2018 01; 127(1):79-91.

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Valderrama J, Miranda R. Early life stress predicts negative urgency through brooding, depending on 5-HTTLPR genotype: A pilot study with 6-month follow-up examining suicide ideation. Psychiatry Res. 2017 12; 258:481-487.

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Cope LM, Munier EC, Trucco EM, Hardee JE, Burmeister M, Zucker RA, Heitzeg MM. Effects of the serotonin transporter gene, sensitivity of response to alcohol, and parental monitoring on risk for problem alcohol use. Alcohol. 2017 03; 59:7-16.

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Trucco EM, Hicks BM, Villafuerte S, Nigg JT, Burmeister M, Zucker RA. Temperament and externalizing behavior as mediators of genetic risk on adolescent substance use. J Abnorm Psychol. 2016 05; 125(4):565-75.

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Kristofco LA, Cruz LC, Haddad SP, Behra ML, Chambliss CK, Brooks BW. Age matters: Developmental stage of Danio rerio larvae influences photomotor response thresholds to diazinion or diphenhydramine. Aquat Toxicol. 2016 Jan; 170:344-354.

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Villalba K, Attonito J, Mendy A, Devieux JG, Gasana J, Dorak TM. A meta-analysis of the associations between the SLC6A4 promoter polymorphism (5HTTLPR) and the risk for alcohol dependence. Psychiatr Genet. 2015 Apr; 25(2):47-58.

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Kranzler HR, Scott D, Tennen H, Feinn R, Williams C, Armeli S, Taylor RE, Briggs-Gowan MJ, Covault J. The 5-HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent. Am J Med Genet B Neuropsychiatr Genet. 2012 Jul; 159B(5):484-90.

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Zhu XY, Etukala JR, Eyunni SV, Setola V, Roth BL, Ablordeppey SY. Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants. Eur J Med Chem. 2012 Jul; 53:124-32.

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Brody GH, Beach SR, Chen YF, Obasi E, Philibert RA, Kogan SM, Simons RL. Perceived discrimination, serotonin transporter linked polymorphic region status, and the development of conduct problems. Dev Psychopathol. 2011 May; 23(2):617-27.

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Babu DK, Diaz A, Samikkannu T, Rao KV, Saiyed ZM, Rodriguez JW, Nair MP. Upregulation of serotonin transporter by alcohol in human dendritic cells: possible implication in neuroimmune deregulation. Alcohol Clin Exp Res. 2009 Oct; 33(10):1731-8.

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