"Laron Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
| Descriptor ID |
D046150
|
| MeSH Number(s) |
C05.116.099.343.679 C16.320.240.750 C19.297.656
|
| Concept/Terms |
Laron Syndrome- Laron Syndrome
- Syndrome, Laron
- Growth Hormone Receptor Defect
- Growth Hormone Receptor Deficiency
- Pituitary Dwarfism II
- Dwarfism II, Pituitary
- Dwarfism IIs, Pituitary
- Pituitary Dwarfism IIs
- Laron Type Dwarfism I
- Primary GH Resistance
- GH Resistance, Primary
- Primary Growth Hormone Resistance
- Severe GH Insensitivity
- Growth Hormone Insensitivity Syndrome
- Laron Dwarfism
- Dwarfism, Laron
|
Below are MeSH descriptors whose meaning is more general than "Laron Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Laron Syndrome".
This graph shows the total number of publications written about "Laron Syndrome" by people in this website by year, and whether "Laron Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Laron Syndrome" by people in Profiles.
-
Tailor K, van Ree J, Stowe T, Ventura B, Sisk C, Courtis J, Camp A, Elzamzami F, van Deursen J, O'Brien R, Baron J, Lui JC. Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity. Front Endocrinol (Lausanne). 2024; 15:1523931.
-
Liu Z, Solesio ME, Schaffler MB, Frikha-Benayed D, Rosen CJ, Werner H, Kopchick JJ, Pavlov EV, Abramov AY, Yakar S. Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice. J Bone Miner Res. 2019 01; 34(1):106-122.
-
Wu Y, Sun H, Basta-Pljakic J, Cardoso L, Kennedy OD, Jasper H, Domen? H, Karabatas L, Guida C, Schaffler MB, Rosen CJ, Yakar S. Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor. J Bone Miner Res. 2013 Jul; 28(7):1575-86.