Monocarboxylic Acid Transporters

"Monocarboxylic Acid Transporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of proteins involved in the transport of monocarboxylic acids such as LACTIC ACID and PYRUVIC ACID across cellular membranes.

Descriptor ID	D027501
MeSH Number(s)	D12.776.157.530.450.074.500.400 D12.776.543.585.450.074.500.300
Concept/Terms	Monocarboxylic Acid Transporters Monocarboxylic Acid Transporters Acid Transporters, Monocarboxylic Transporters, Monocarboxylic Acid Monocarboxylate Translocator Translocator, Monocarboxylate Monocarboxylic Acid Transport Proteins MCT Proteins Monocarboxylic Acid Transport Protein Erythrocyte Lactate Transporters Erythrocyte Lactate Transporters Lactate Transporters, Erythrocyte Transporters, Erythrocyte Lactate Erythrocyte Lactate Transporter Lactate Transporter, Erythrocyte Transporter, Erythrocyte Lactate Lactate Transport Proteins Lactate Transport Proteins Transport Proteins, Lactate Lactate Transport Protein Transport Protein, Lactate Lactate Transporter Transporter, Lactate Lactate Translocase Translocase, Lactate

Below are MeSH descriptors whose meaning is more general than "Monocarboxylic Acid Transporters".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Pumps [D12.776.157.530.450]
Anion Transport Proteins [D12.776.157.530.450.074]
Organic Anion Transporters [D12.776.157.530.450.074.500]
Monocarboxylic Acid Transporters [D12.776.157.530.450.074.500.400]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Ion Pumps [D12.776.543.585.450]
Anion Transport Proteins [D12.776.543.585.450.074]
Organic Anion Transporters [D12.776.543.585.450.074.500]
Monocarboxylic Acid Transporters [D12.776.543.585.450.074.500.300]

Below are MeSH descriptors whose meaning is related to "Monocarboxylic Acid Transporters".

Below are MeSH descriptors whose meaning is more specific than "Monocarboxylic Acid Transporters".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Monocarboxylic Acid Transporters" by people in this website by year, and whether "Monocarboxylic Acid Transporters" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 2005 and 2007 and 2010 and 2011 and 2016 and 2019 and 2021 and 2022 and 2025

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2007	0	1	1
2010	1	0	1
2011	0	1	1
2016	1	0	1
2019	0	1	1
2021	1	0	1
2022	1	0	1
2025	0	1	1

Below are the most recent publications written about "Monocarboxylic Acid Transporters" by people in Profiles.

da Silva RAG, Tien BYQ, Kao PHN, Antypas H, Celik C, Tan AZC, Ismail MH, Hu G, Chong KKL, Thibault G, Chen J, Kline KA. Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections. Cell Host Microbe. 2026 Feb 11; 34(2):245-262.e8.

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Yasukawa K, Shimada S, Akiyama Y, Taniai T, Igarashi Y, Tsukihara S, Tanji Y, Umemura K, Kamachi A, Nara A, Yamane M, Akahoshi K, Shimizu A, Soejima Y, Tanabe M, Tanaka S. ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T?cells in hepatocellular carcinoma. Cell Rep Med. 2025 Apr 15; 6(4):102038.

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Hao Q, Huang Z, Li Q, Liu D, Wang P, Wang K, Li J, Cao W, Deng W, Wu K, Su R, Liu Z, Vadgama J, Wu Y. A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes-Associated Breast Cancer. Adv Sci (Weinh). 2022 02; 9(6):e2102303.

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Xu L, Phelix CF, Chen LY. Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes. J Chem Inf Model. 2021 11 22; 61(11):5614-5625.

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Turner TL, Lane S, Jayakody LN, Zhang GC, Kim H, Cho W, Jin YS. Deletion of JEN1 and ADY2 reduces lactic acid yield from an engineered Saccharomyces cerevisiae, in xylose medium, expressing a heterologous lactate dehydrogenase. FEMS Yeast Res. 2019 09 01; 19(6).

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Shima T, Jesmin S, Matsui T, Soya M, Soya H. Differential effects of type 2 diabetes on brain glycometabolism in rats: focus on glycogen and monocarboxylate transporter 2. J Physiol Sci. 2018 Jan; 68(1):69-75.

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Brim H, Kumar K, Nazarian J, Hathout Y, Jafarian A, Lee E, Green W, Smoot D, Park J, Nouraie M, Ashktorab H. SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas. PLoS One. 2011; 6(6):e20216.

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McDermott JR, Rosen BP, Liu Z. Jen1p: a high affinity selenite transporter in yeast. Mol Biol Cell. 2010 Nov 15; 21(22):3934-41.

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Davidow LS, Breen M, Duke SE, Samollow PB, McCarrey JR, Lee JT. The search for a marsupial XIC reveals a break with vertebrate synteny. Chromosome Res. 2007; 15(2):137-46.

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Hong C, Maunakea A, Jun P, Bollen AW, Hodgson JG, Goldenberg DD, Weiss WA, Costello JF. Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8. Cancer Res. 2005 May 01; 65(9):3617-23.

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