alpha-Tocopherol

"alpha-Tocopherol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.

Descriptor ID	D024502
MeSH Number(s)	D03.383.663.283.909.750.249 D03.633.100.150.909.750.249
Concept/Terms	alpha-Tocopherol alpha-Tocopherol alpha Tocopherol 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol alpha-Tocopheryl Calcium Succinate alpha-Tocopheryl Calcium Succinate Calcium Succinate, alpha-Tocopheryl alpha Tocopheryl Calcium Succinate alpha-Tocopherol Acetate alpha-Tocopherol Acetate alpha Tocopherol Acetate Tocopheryl Acetate Tocopherol Acetate Acetate, Tocopherol d-alpha-Tocopheryl Acetate d-alpha-Tocopheryl Acetate d alpha Tocopheryl Acetate alpha-Tocopherol Succinate alpha-Tocopherol Succinate alpha Tocopherol Succinate Tocopherol Succinate Succinate, Tocopherol alpha-Tocopherol Hemisuccinate alpha Tocopherol Hemisuccinate d-alpha Tocopherol d-alpha Tocopherol Tocopherol, d-alpha d alpha Tocopherol R,R,R-alpha-Tocopherol

Below are MeSH descriptors whose meaning is more general than "alpha-Tocopherol".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrans [D03.383.663]
Benzopyrans [D03.383.663.283]
Vitamin E [D03.383.663.283.909]
Tocopherols [D03.383.663.283.909.750]
alpha-Tocopherol [D03.383.663.283.909.750.249]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzopyrans [D03.633.100.150]
Vitamin E [D03.633.100.150.909]
Tocopherols [D03.633.100.150.909.750]
alpha-Tocopherol [D03.633.100.150.909.750.249]

Below are MeSH descriptors whose meaning is related to "alpha-Tocopherol".

Below are MeSH descriptors whose meaning is more specific than "alpha-Tocopherol".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "alpha-Tocopherol" by people in this website by year, and whether "alpha-Tocopherol" was a major or minor topic of these publications.

Bar chart showing 23 publications over 12 distinct years, with a maximum of 4 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2003	1	0	1
2004	1	1	2
2006	0	1	1
2007	0	1	1
2008	2	2	4
2009	2	1	3
2010	1	2	3
2011	0	2	2
2012	1	1	2
2013	1	0	1
2014	2	0	2

Below are the most recent publications written about "alpha-Tocopherol" by people in Profiles.

Chai W, Novotny R, Maskarinec G, Le Marchand L, Franke AA, Cooney RV. Serum coenzyme Q10, a-tocopherol, ?-tocopherol, and C-reactive protein levels and body mass index in adolescent and premenopausal females. J Am Coll Nutr. 2014; 33(3):192-7.

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Marchese ME, Kumar R, Colangelo LA, Avila PC, Jacobs DR, Gross M, Sood A, Liu K, Cook-Mills JM. The vitamin E isoforms a-tocopherol and ?-tocopherol have opposite associations with spirometric parameters: the CARDIA study. Respir Res. 2014 Mar 15; 15:31.

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Bell EF, Hansen NI, Brion LP, Ehrenkranz RA, Kennedy KA, Walsh MC, Shankaran S, Acarregui MJ, Johnson KJ, Hale EC, Messina LA, Crawford MM, Laptook AR, Goldberg RN, Van Meurs KP, Carlo WA, Poindexter BB, Faix RG, Carlton DP, Watterberg KL, Ellsbury DL, Das A, Higgins RD. Serum tocopherol levels in very preterm infants after a single dose of vitamin E at birth. Pediatrics. 2013 Dec; 132(6):e1626-33.

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Cook MB, Kamangar F, Weinstein SJ, Albanes D, Virtamo J, Taylor PR, Abnet CC, Wood RJ, Petty G, Cross AJ, Dawsey SM. Iron in relation to gastric cancer in the Alpha-tocopherol, Beta-carotene Cancer Prevention Study. Cancer Epidemiol Biomarkers Prev. 2012 Nov; 21(11):2033-42.

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Xiong A, Yu W, Tiwary R, Sanders BG, Kline K. Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells. Mol Nutr Food Res. 2012 Jun; 56(6):923-34.

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Tiwary R, Yu W, deGraffenried LA, Sanders BG, Kline K. Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer. Breast Cancer Res. 2011; 13(6):R120.

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Cooney RV, Dai Q, Gao YT, Chow WH, Franke AA, Shu XO, Li H, Ji B, Cai Q, Chai W, Zheng W. Low plasma coenzyme Q(10) levels and breast cancer risk in Chinese women. Cancer Epidemiol Biomarkers Prev. 2011 Jun; 20(6):1124-30.

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Tiwary R, Yu W, Sanders BG, Kline K. a-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways. Br J Cancer. 2011 Jan 04; 104(1):101-9.

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Cook MB, Dawsey SM, Diaw L, Blaser MJ, Perez-Perez GI, Abnet CC, Taylor PR, Albanes D, Virtamo J, Kamangar F. Serum pepsinogens and Helicobacter pylori in relation to the risk of esophageal squamous cell carcinoma in the alpha-tocopherol, beta-carotene cancer prevention study. Cancer Epidemiol Biomarkers Prev. 2010 Aug; 19(8):1966-75.

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Dodge HH, Katsumata Y, Todoriki H, Yasura S, Willcox DC, Bowman GL, Willcox B, Leonard S, Clemons A, Oken BS, Kaye JA, Traber MG. Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot study. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1060-7.

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