H(+)-K(+)-Exchanging ATPase
"H(+)-K(+)-Exchanging ATPase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme isolated from the GASTRIC MUCOSA that catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions across the cell wall. This enzyme was formerly listed as EC 3.6.1.36.
Descriptor ID |
D017506
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MeSH Number(s) |
D08.811.277.040.025.314.625 D12.776.157.530.450.250.875.500.625 D12.776.157.530.813.625 D12.776.543.585.450.250.875.500.625 D12.776.543.585.813.625
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Concept/Terms |
H(+)-K(+)-Exchanging ATPase- H(+)-K(+)-Exchanging ATPase
- Potassium Hydrogen ATPase
- ATPase, Potassium Hydrogen
- ATPase, Hydrogen, Potassium
- Hydrogen, Potassium ATPase
- ATPase Hydrogen, Potassium
- Adenosinetriphosphatase, Hydrogen, Potassium
- Hydrogen-Potassium-Exchanging ATPase
- ATPase, Hydrogen-Potassium-Exchanging
- Hydrogen Potassium Exchanging ATPase
- H(+)-K(+)-Transporting ATPase
- Adenosine Triphosphatase, Hydrogen, Potassium
- Hydrogen, Potassium, Adenosine Triphosphatase
- Gastric H(+) K(+) ATPase
- Hydrogen, Potassium, Adenosinetriphosphatase
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Below are MeSH descriptors whose meaning is more general than "H(+)-K(+)-Exchanging ATPase".
Below are MeSH descriptors whose meaning is more specific than "H(+)-K(+)-Exchanging ATPase".
This graph shows the total number of publications written about "H(+)-K(+)-Exchanging ATPase" by people in this website by year, and whether "H(+)-K(+)-Exchanging ATPase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 |
2002 | 0 | 3 | 3 |
2005 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "H(+)-K(+)-Exchanging ATPase" by people in Profiles.
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Yuan X, Yao PY, Jiang J, Zhang Y, Su Z, Yao W, Wang X, Gui P, Mullen M, Henry C, Ward T, Wang W, Brako L, Tian R, Zhao X, Wang F, Cao X, Wang D, Liu X, Ding X, Yao X. MST4 kinase phosphorylates ACAP4 protein to orchestrate apical membrane remodeling during gastric acid secretion. J Biol Chem. 2017 09 29; 292(39):16174-16187.
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Yu H, Zhou J, Takahashi H, Yao W, Suzuki Y, Yuan X, Yoshimura SH, Zhang Y, Liu Y, Emmett N, Bond V, Wang D, Ding X, Takeyasu K, Yao X. Spatial control of proton pump H,K-ATPase docking at the apical membrane by phosphorylation-coupled ezrin-syntaxin 3 interaction. J Biol Chem. 2014 Nov 28; 289(48):33333-42.
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Ding X, Wu F, Guo Z, Yao X. Molecular dissection of HCl secretion in gastric parietal cells using streptolysin O permeabilization. Methods Mol Biol. 2008; 440:217-26.
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Zhou R, Zhu L, Kodani A, Hauser P, Yao X, Forte JG. Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J Cell Sci. 2005 Oct 01; 118(Pt 19):4381-91.
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Karvar S, Yao X, Crothers JM, Liu Y, Forte JG. Localization and function of soluble N-ethylmaleimide-sensitive factor attachment protein-25 and vesicle-associated membrane protein-2 in functioning gastric parietal cells. J Biol Chem. 2002 Dec 20; 277(51):50030-5.
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Karvar S, Yao X, Duman JG, Hybiske K, Liu Y, Forte JG. Intracellular distribution and functional importance of vesicle-associated membrane protein 2 in gastric parietal cells. Gastroenterology. 2002 Jul; 123(1):281-90.
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Ammar DA, Zhou R, Forte JG, Yao X. Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland model. Am J Physiol Gastrointest Liver Physiol. 2002 Jan; 282(1):G23-33.
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Rulli SJ, Louneva NM, Skripnikova EV, Rabon EC. Site-directed mutagenesis of cation coordinating residues in the gastric H,K-ATPase. Arch Biochem Biophys. 2001 Mar 01; 387(1):27-34.