Mitomycin

"Mitomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.

Descriptor ID	D016685
MeSH Number(s)	D02.806.400.249.350 D03.383.097.500.350 D03.633.100.473.412.249.350
Concept/Terms	Mitomycin Mitomycin Mitomycin C Mitomycin-C Mitocin-C Mitocin-C Mitocin C MitocinC NSC-26980 NSC-26980 NSC 26980 NSC26980 Ametycine Ametycine Mutamycin Mutamycin

Below are MeSH descriptors whose meaning is more general than "Mitomycin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Quinones [D02.806]
Indolequinones [D02.806.400]
Mitomycins [D02.806.400.249]
Mitomycin [D02.806.400.249.350]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azirines [D03.383.097]
Mitomycins [D03.383.097.500]
Mitomycin [D03.383.097.500.350]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Indolequinones [D03.633.100.473.412]
Mitomycins [D03.633.100.473.412.249]
Mitomycin [D03.633.100.473.412.249.350]

Below are MeSH descriptors whose meaning is related to "Mitomycin".

Below are MeSH descriptors whose meaning is more specific than "Mitomycin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mitomycin" by people in this website by year, and whether "Mitomycin" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2007	0	1	1
2008	1	0	1
2010	0	1	1
2013	1	0	1
2014	2	0	2
2015	1	0	1
2016	0	1	1
2018	1	0	1

Below are the most recent publications written about "Mitomycin" by people in Profiles.

Nguyen AH, Fatehi N, Romero P, Miraftabi A, Kim E, Morales E, Giaconi J, Coleman AL, Law SK, Caprioli J, Nouri-Mahdavi K. Observational Outcomes of Initial Trabeculectomy With Mitomycin C in Patients of African Descent vs Patients of European Descent: Five-Year Results. JAMA Ophthalmol. 2018 10 01; 136(10):1106-1113.

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Nowacki M, Alyami M, Villeneuve L, Mercier F, Hubner M, Willaert W, Ceelen W, Reymond M, Pezet D, Arvieux C, Khomyakov V, Lay L, Gianni S, Zegarski W, Bakrin N, Glehen O. Multicenter comprehensive methodological and technical analysis of?832 pressurized intraperitoneal aerosol chemotherapy (PIPAC) interventions performed in 349 patients for peritoneal carcinomatosis treatment: An international survey study. Eur J Surg Oncol. 2018 07; 44(7):991-996.

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Song BJ, Ramanathan M, Morales E, Law SK, Giaconi JA, Coleman AL, Caprioli J. Trabeculectomy and Combined Phacoemulsification-Trabeculectomy: Outcomes and Risk Factors for Failure in Primary Angle Closure Glaucoma. J Glaucoma. 2016 09; 25(9):763-9.

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Habibollahi A, Hashemi H, Seyedian MA, Mehravaran S, Asgari S, Habibollahi S, Habibollahi S, Khabazkhoob M. One Year Outcomes of Photorefractive Keratectomy with the Application of Mitomycin-C in the Treatment of Mild to Moderate Hyperopia. Middle East Afr J Ophthalmol. 2015 Oct-Dec; 22(4):484-8.

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Nassiri N, Sheibani K, Safi S, Haghnegahdar M, Nassiri S, Panahi N, Mehravaran S, Nassiri N. Alcohol-assisted debridement in PRK with intraoperative mitomycin C. Optom Vis Sci. 2014 Sep; 91(9):1084-8.

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Kwong A, Law SK, Kule RR, Nouri-Mahdavi K, Coleman AL, Caprioli J, Giaconi JA. Long-term outcomes of resident- versus attending-performed primary trabeculectomy with mitomycin C in a United States residency program. Am J Ophthalmol. 2014 Jun; 157(6):1190-201.

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Farahi A, Hashemi H, Mehravaran S. The effects of mitomycin C on tear function after photorefractive keratectomy: a contralateral comparative study. J Refract Surg. 2013 Apr; 29(4):260-4.

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Boamah EK, Brekman A, Tomasz M, Myeku N, Figueiredo-Pereira M, Hunter S, Meyer J, Bhosle RC, Bargonetti J. DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1. Chem Res Toxicol. 2010 Jul 19; 23(7):1151-62.

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Paz MM, Ladwa S, Champeil E, Liu Y, Rockwell S, Boamah EK, Bargonetti J, Callahan J, Roach J, Tomasz M. Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry. Chem Res Toxicol. 2008 Dec; 21(12):2370-8.

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Law SK, Nguyen AM, Coleman AL, Caprioli J. Severe loss of central vision in patients with advanced glaucoma undergoing trabeculectomy. Arch Ophthalmol. 2007 Aug; 125(8):1044-50.

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