"Ofloxacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
| Descriptor ID |
D015242
|
| MeSH Number(s) |
D03.633.100.810.835.322.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ofloxacin".
Below are MeSH descriptors whose meaning is more specific than "Ofloxacin".
This graph shows the total number of publications written about "Ofloxacin" by people in this website by year, and whether "Ofloxacin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ofloxacin" by people in Profiles.
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Erova TE, Rosenzweig JA, Sha J, Suarez G, Sierra JC, Kirtley ML, van Lier CJ, Telepnev MV, Motin VL, Chopra AK. Evaluation of protective potential of Yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine. Clin Vaccine Immunol. 2013 Feb; 20(2):227-38.
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Sha J, Rosenzweig JA, Kirtley ML, van Lier CJ, Fitts EC, Kozlova EV, Erova TE, Tiner BL, Chopra AK. A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague. Microb Pathog. 2013 Feb; 55:39-50.
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Rosenzweig JA, Brackman SM, Kirtley ML, Sha J, Erova TE, Yeager LA, Peterson JW, Xu ZQ, Chopra AK. Cethromycin-mediated protection against the plague pathogen Yersinia pestis in a rat model of infection and comparison with levofloxacin. Antimicrob Agents Chemother. 2011 Nov; 55(11):5034-42.
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Griffith ME, Moon JE, Johnson EN, Clark KP, Hawley JS, Hospenthal DR, Murray CK. Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model. Antimicrob Agents Chemother. 2007 Jul; 51(7):2615-7.
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Mulla ZD. Group A streptococcal pneumonia. Arch Intern Med. 2003 Sep 22; 163(17):2101; author reply 2101-2.
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Zheng X, Johnson C, Lu Y, Yanagihara R, Hollingshead S, Crain M, Benjamin W, Waites KB. Clinical isolates of Streptococcus pneumoniae resistant to levofloxacin contain mutations in both gyrA and parC genes. Int J Antimicrob Agents. 2001 Oct; 18(4):373-8.
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Son DS, Ikenoue N, Tagawa Y, Shimoda M, Kokue E. Non-linear pharmacokinetics of ofloxacin after a single intravenous bolus dose in pigs. J Vet Pharmacol Ther. 2000 Oct; 23(5):311-5.