DNA-Directed RNA Polymerases

"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).

Descriptor ID	D012321
MeSH Number(s)	D08.811.913.696.445.735.270
Concept/Terms	DNA-Directed RNA Polymerases DNA-Directed RNA Polymerases DNA Directed RNA Polymerases Polymerases, DNA-Directed RNA RNA Polymerases, DNA-Directed RNA Polymerase Polymerase, RNA Transcriptases DNA-Directed RNA Polymerase DNA Directed RNA Polymerase Polymerase, DNA-Directed RNA RNA Polymerase, DNA-Directed DNA-Dependent RNA Polymerases DNA Dependent RNA Polymerases Polymerases, DNA-Dependent RNA RNA Polymerases, DNA-Dependent RNA Polymerases Polymerases, RNA Transcriptase Transcriptase

Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Nucleotidyltransferases [D08.811.913.696.445]
RNA Nucleotidyltransferases [D08.811.913.696.445.735]
DNA-Directed RNA Polymerases [D08.811.913.696.445.735.270]

Below are MeSH descriptors whose meaning is related to "DNA-Directed RNA Polymerases".

Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.

Bar chart showing 18 publications over 11 distinct years, with a maximum of 4 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	3	1	4
2000	1	1	2
2001	1	1	2
2003	1	0	1
2008	0	1	1
2010	0	1	1
2011	0	1	1
2014	1	1	2
2017	2	0	2
2018	0	1	1

Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.

Campos-Gomez J, Benitez JA. A simple cell-based high throughput screening (HTS) assay for inhibitors of Salmonella enterica RNA polymerase containing the general stress response regulator RpoS (sS). J Microbiol Methods. 2018 07; 150:1-4.

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Richard CA, Rincheval V, Lassoued S, Fix J, Cardone C, Esneau C, Nekhai S, Galloux M, Rameix-Welti MA, Sizun C, El?ou?t JF. RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription. PLoS Pathog. 2018 03; 14(3):e1006920.

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Abanda NN, Djieugou? JY, Khadka VS, Pefura-Yone EW, Mbacham WF, Vernet G, Penlap VM, Deng Y, Eyangoh SI, Taylor DW, Leke RGF. Absence of hybridization with the wild-type and mutant rpoB probes in the Genotype MTBDRplus assay detects 'disputed' rifampicin mutations. Clin Microbiol Infect. 2018 Jul; 24(7):781.e1-781.e3.

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Alphonse S, Ghose R. Cystoviral RNA-directed RNA polymerases: Regulation of RNA synthesis on multiple time and length scales. Virus Res. 2017 04 15; 234:135-152.

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Giampietro PF, Armstrong L, Stoddard A, Blank RD, Livingston J, Raggio CL, Rasmussen K, Pickart M, Lorier R, Turner A, Sund S, Sobrera N, Neptune E, Sweetser D, Santiago-Cornier A, Broeckel U. Whole exome sequencing identifies a POLRID mutation segregating in a father and two daughters with findings of Klippel-Feil and Treacher Collins syndromes. Am J Med Genet A. 2015 Jan; 167A(1):95-102.

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Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A. Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription. J Biol Chem. 2014 Aug 15; 289(33):22723-22738.

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Wang H, Zhang L, Silva AJ, Benitez JA. A quinazoline-2,4-diamino analog suppresses Vibrio cholerae flagellar motility by interacting with motor protein PomB and induces envelope stress. Antimicrob Agents Chemother. 2013 Aug; 57(8):3950-9.

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Wang J, Chen WF, Li QX. Rapid identification and classification of Mycobacterium spp. using whole-cell protein barcodes with matrix assisted laser desorption ionization time of flight mass spectrometry in comparison with multigene phylogenetic analysis. Anal Chim Acta. 2012 Feb 24; 716:133-7.

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Karna SL, Zogaj X, Barker JR, Seshu J, Dove SL, Klose KE. A bacterial two-hybrid system that utilizes Gateway cloning for rapid screening of protein-protein interactions. Biotechniques. 2010 Nov; 49(5):831-3.

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Kralj JG, Player A, Sedrick H, Munson MS, Petersen D, Forry SP, Meltzer P, Kawasaki E, Locascio LE. T7-based linear amplification of low concentration mRNA samples using beads and microfluidics for global gene expression measurements. Lab Chip. 2009 Apr 07; 9(7):917-24.

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