DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
Descriptor ID |
D012321
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MeSH Number(s) |
D08.811.913.696.445.735.270
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Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
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Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1998 | 3 | 1 | 4 |
1999 | 0 | 1 | 1 |
2000 | 1 | 1 | 2 |
2001 | 1 | 1 | 2 |
2003 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2014 | 2 | 1 | 3 |
2017 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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Campos-Gomez J, Benitez JA. A simple cell-based high throughput screening (HTS) assay for inhibitors of Salmonella enterica RNA polymerase containing the general stress response regulator RpoS (sS). J Microbiol Methods. 2018 07; 150:1-4.
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Richard CA, Rincheval V, Lassoued S, Fix J, Cardone C, Esneau C, Nekhai S, Galloux M, Rameix-Welti MA, Sizun C, El?ou?t JF. RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription. PLoS Pathog. 2018 03; 14(3):e1006920.
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Alphonse S, Ghose R. Cystoviral RNA-directed RNA polymerases: Regulation of RNA synthesis on multiple time and length scales. Virus Res. 2017 04 15; 234:135-152.
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Giampietro PF, Armstrong L, Stoddard A, Blank RD, Livingston J, Raggio CL, Rasmussen K, Pickart M, Lorier R, Turner A, Sund S, Sobrera N, Neptune E, Sweetser D, Santiago-Cornier A, Broeckel U. Whole exome sequencing identifies a POLRID mutation segregating in a father and two daughters with findings of Klippel-Feil and Treacher Collins syndromes. Am J Med Genet A. 2015 Jan; 167A(1):95-102.
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Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A. Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription. J Biol Chem. 2014 Aug 15; 289(33):22723-22738.
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Shimada T, Yamazaki Y, Tanaka K, Ishihama A. The whole set of constitutive promoters recognized by RNA polymerase RpoD holoenzyme of Escherichia coli. PLoS One. 2014; 9(3):e90447.
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Wang H, Zhang L, Silva AJ, Benitez JA. A quinazoline-2,4-diamino analog suppresses Vibrio cholerae flagellar motility by interacting with motor protein PomB and induces envelope stress. Antimicrob Agents Chemother. 2013 Aug; 57(8):3950-9.
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Wang J, Chen WF, Li QX. Rapid identification and classification of Mycobacterium spp. using whole-cell protein barcodes with matrix assisted laser desorption ionization time of flight mass spectrometry in comparison with multigene phylogenetic analysis. Anal Chim Acta. 2012 Feb 24; 716:133-7.
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Karna SL, Zogaj X, Barker JR, Seshu J, Dove SL, Klose KE. A bacterial two-hybrid system that utilizes Gateway cloning for rapid screening of protein-protein interactions. Biotechniques. 2010 Nov; 49(5):831-3.
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Lu YA, Wang Y, Aguirre AA, Zhao ZS, Liu CY, Nerurkar VR, Yanagihara R. RT-PCR detection of the expression of the polymerase gene of a novel reptilian herpesvirus in tumor tissues of green turtles with fibropapilloma. Arch Virol. 2003 Jun; 148(6):1155-63.