"Probenecid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
| Descriptor ID |
D011339
|
| MeSH Number(s) |
D02.065.884.625 D02.886.590.700.625
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Probenecid".
Below are MeSH descriptors whose meaning is more specific than "Probenecid".
This graph shows the total number of publications written about "Probenecid" by people in this website by year, and whether "Probenecid" was a major or minor topic of these publications.
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Below are the most recent publications written about "Probenecid" by people in Profiles.
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Radziszewski W, Chopra M, Zembowicz A, Gryglewski R, Ignarro LJ, Chaudhuri G. Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. Int J Cardiol. 1995 Oct; 51(3):211-20.