"Molsidomine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
| Descriptor ID |
D008981
|
| MeSH Number(s) |
D03.383.129.462.580.693.450 D03.383.533.640.362
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Molsidomine".
Below are MeSH descriptors whose meaning is more specific than "Molsidomine".
This graph shows the total number of publications written about "Molsidomine" by people in this website by year, and whether "Molsidomine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Molsidomine" by people in Profiles.
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Kovanecz I, Rivera S, Nolazco G, Vernet D, Segura D, Gharib S, Rajfer J, Gonzalez-Cadavid NF. Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve damage. J Sex Med. 2012 Nov; 9(11):2814-26.
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Ferrini MG, Moon J, Rivera S, Rajfer J, Gonzalez-Cadavid NF. Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-?1 therapies in inducible nitric oxide synthase-deficient mice. BJU Int. 2012 Feb; 109(4):586-93.
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Richardson SM, Maleque MA, Motley ED. 3-Morpholinosyndnonimine inhibits 5-hydroxytryptamine-induced phosphorylation of nitric oxide synthase in endothelial cells. Cell Mol Biol (Noisy-le-grand). 2003 Dec; 49(8):1385-9.
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Farias-Eisner R, Chaudhuri G, Aeberhard E, Fukuto JM. The chemistry and tumoricidal activity of nitric oxide/hydrogen peroxide and the implications to cell resistance/susceptibility. J Biol Chem. 1996 Mar 15; 271(11):6144-51.
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Radziszewski W, Chopra M, Zembowicz A, Gryglewski R, Ignarro LJ, Chaudhuri G. Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. Int J Cardiol. 1995 Oct; 51(3):211-20.