"Lyme Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
| Descriptor ID |
D008193
|
| MeSH Number(s) |
C01.252.400.155.569 C01.252.400.825.480 C01.252.847.193.569
|
| Concept/Terms |
Lyme Disease- Lyme Disease
- Disease, Lyme
- B. burgdorferi Infection
- B. burgdorferi Infections
- Lyme Borreliosis
- Borreliosis, Lyme
- Borrelia burgdorferi Infection
- Borrelia burgdorferi Infections
|
Below are MeSH descriptors whose meaning is more general than "Lyme Disease".
Below are MeSH descriptors whose meaning is more specific than "Lyme Disease".
This graph shows the total number of publications written about "Lyme Disease" by people in this website by year, and whether "Lyme Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lyme Disease" by people in Profiles.
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Kumaresan V, Ingle TM, Kilgore N, Zhang G, Hermann BP, Seshu J. Cellular and transcriptome signatures unveiled by single-cell RNA-Seq following ex vivo infection of murine splenocytes with Borrelia burgdorferi. Front Immunol. 2023; 14:1296580.
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Porter WT, Barrand ZA, Wachara J, DaVall K, Mihaljevic JR, Pearson T, Salkeld DJ, Nieto NC. Predicting the current and future distribution of the western black-legged tick, Ixodes pacificus, across the Western US using citizen science collections. PLoS One. 2021; 16(1):e0244754.
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Gupta S, Eggers P, Arana A, Kresse B, Rios K, Brown L, Sampson L, Kploanyi M. Knowledge and preventive behaviors towards tick-borne diseases in Delaware. Ticks Tick Borne Dis. 2018 03; 9(3):615-622.
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Seshu J, Smith TC, Lin YH, Karna SLR, Miller CL, Van Laar T. Analysis of DNA and RNA Binding Properties of Borrelia burgdorferi Regulatory Proteins. Methods Mol Biol. 2018; 1690:155-175.
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Lin YH, Romo JA, Smith TC, Reyes AN, Karna SLR, Miller CL, Van Laar TA, Yendapally R, Chambers JP, Seshu J. Spermine and Spermidine Alter Gene Expression and Antigenic Profile of Borrelia burgdorferi. Infect Immun. 2017 03; 85(3).
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Qiu WG, Martin CL. Evolutionary genomics of Borrelia burgdorferi sensu lato: findings, hypotheses, and the rise of hybrids. Infect Genet Evol. 2014 Oct; 27:576-93.
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Raju BV, Esteve-Gassent MD, Karna SL, Miller CL, Van Laar TA, Seshu J. Oligopeptide permease A5 modulates vertebrate host-specific adaptation of Borrelia burgdorferi. Infect Immun. 2011 Aug; 79(8):3407-20.
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Karna SL, Sanjuan E, Esteve-Gassent MD, Miller CL, Maruskova M, Seshu J. CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi. Infect Immun. 2011 Feb; 79(2):732-44.
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Esteve-Gassent MD, Elliott NL, Seshu J. sodA is essential for virulence of Borrelia burgdorferi in the murine model of Lyme disease. Mol Microbiol. 2009 Feb; 71(3):594-612.
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Maruskova M, Seshu J. Deletion of BBA64, BBA65, and BBA66 loci does not alter the infectivity of Borrelia burgdorferi in the murine model of Lyme disease. Infect Immun. 2008 Nov; 76(11):5274-84.