"Clioquinol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
| Descriptor ID |
D007464
|
| MeSH Number(s) |
D03.633.100.810.350.625.400
|
| Concept/Terms |
Clioquinol- Clioquinol
- 5-Chloro-7-iodo-8-quinolinol
- 5 Chloro 7 iodo 8 quinolinol
- Iodochloroxyquinoline
- Chloroiodoquine
- Iodochlorhydroxyquin
|
Below are MeSH descriptors whose meaning is more general than "Clioquinol".
Below are MeSH descriptors whose meaning is more specific than "Clioquinol".
This graph shows the total number of publications written about "Clioquinol" by people in this website by year, and whether "Clioquinol" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clioquinol" by people in Profiles.
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Kehinde IA, Egbeyemi A, Kaur M, Onyenaka C, Adebusuyi T, Olaleye OA. Inhibitory mechanism of clioquinol and its derivatives at the exopeptidase site of human angiotensin-converting enzyme-2 and receptor binding domain of SARS-CoV-2 viral spike. J Biomol Struct Dyn. 2023 04; 41(7):2992-3001.
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Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinb). 2011 Dec; 91 Suppl 1:S61-5.