Ethinyl Estradiol

"Ethinyl Estradiol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES.

Descriptor ID	D004997
MeSH Number(s)	D04.210.500.668.651.568.291 D06.472.334.851.437.968.500
Concept/Terms	Ethinyl Estradiol Ethinyl Estradiol Estradiol, Ethinyl Ethinyloestradiol Ethynyl Estradiol Estradiol, Ethynyl Ethinyl Estradiol Hemihydrate Ethinyl Estradiol Hemihydrate Hemihydrate, Ethinyl Estradiol Ethinyl Estradiol, (8 alpha)-Isomer Ethinyl Estradiol, (8 alpha)-Isomer Ethinyl Estradiol, (8 alpha,17 alpha)-Isomer Ethinyl Estradiol, (8 alpha,17 alpha)-Isomer Ethinyl Estradiol, (8 alpha,9 beta,13 alpha,14 beta)-Isomer Ethinyl Estradiol, (8 alpha,9 beta,13 alpha,14 beta)-Isomer Progynon C Progynon C Microfollin Microfollin Microfollin Forte Microfollin Forte Ethinyl-Oestradiol Effik Ethinyl-Oestradiol Effik Ethinyl Oestradiol Effik Ethinylestradiol Jenapharm Ethinylestradiol Jenapharm Jenapharm, Ethinylestradiol Lynoral Lynoral Estinyl Estinyl Ethinyl Estradiol, (9 beta,17 alpha)-Isomer Ethinyl Estradiol, (9 beta,17 alpha)-Isomer

Below are MeSH descriptors whose meaning is more general than "Ethinyl Estradiol".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Norsteroids [D04.210.500.668]
Norpregnanes [D04.210.500.668.651]
Norpregnatrienes [D04.210.500.668.651.568]
Ethinyl Estradiol [D04.210.500.668.651.568.291]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Gonadal Hormones [D06.472.334]
Gonadal Steroid Hormones [D06.472.334.851]
Estradiol Congeners [D06.472.334.851.437]
Estrogenic Steroids, Alkylated [D06.472.334.851.437.968]
Ethinyl Estradiol [D06.472.334.851.437.968.500]

Below are MeSH descriptors whose meaning is related to "Ethinyl Estradiol".

Below are MeSH descriptors whose meaning is more specific than "Ethinyl Estradiol".

Ethinyl Estradiol
Ethinyl Estradiol-Norgestrel Combination
Mestranol
Quinestrol

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ethinyl Estradiol" by people in this website by year, and whether "Ethinyl Estradiol" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2002 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	1	2
2008	0	1	1
2009	1	0	1
2011	1	0	1
2012	0	1	1
2020	1	1	2
2025	1	0	1

Below are the most recent publications written about "Ethinyl Estradiol" by people in Profiles.

Tobin NH, Brooker SL, Li F, Coombs RW, Cohn SE, Moran L, Leon M, Chotirosniramit N, Jalil EM, Chakalisa UA, Scarsi KK, Zorrilla CD, Godfrey C, Aldrovandi GM. Use of an Ethinyl Estradiol/Etonogestrel Vaginal Ring Alters Vaginal Microbial Communities in Women With HIV. J Infect Dis. 2025 Mar 17; 231(3):583-594.

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Haas DW, Cramer YS, Godfrey C, Rosenkranz SL, Aweeka F, Berzins B, Coombs R, Coughlin K, Moran LE, Gingrich D, Zorrilla CD, Baker P, Cohn SE, Scarsi KK. Pharmacogenetic interactions between antiretroviral drugs and vaginally administered hormonal contraceptives. Pharmacogenet Genomics. 2020 04; 30(3):45-53.

View in: PubMed
Lin PH, Kuo TH, Chen CC, Jian CY, Chen CW, Wang KL, Kuo YC, Shen HY, Hsia SM, Wang PS, Lieu FK, Wang SW. Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17a-ethynylestradiol. Sci Rep. 2020 01 31; 10(1):1576.

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Wang G, Ma P, Zhang Q, Lewis J, Lacey M, Furukawa Y, O'Reilly SE, Meaux S, McLachlan J, Zhang S. Endocrine disrupting chemicals in New Orleans surface waters and Mississippi Sound sediments. J Environ Monit. 2012 May; 14(5):1353-64.

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Kaneshiro B, Edelman A, Carlson NE, Nichols M, Forbes MM, Jensen J. A randomized controlled trial of subantimicrobial-dose doxycycline to prevent unscheduled bleeding with continuous oral contraceptive pill use. Contraception. 2012 Apr; 85(4):351-8.

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Mathews E, Braden TD, Williams CS, Williams JW, Bolden-Tiller O, Goyal HO. Mal-development of the penis and loss of fertility in male rats treated neonatally with female contraceptive 17alpha-ethinyl estradiol: a dose-response study and a comparative study with a known estrogenic teratogen diethylstilbestrol. Toxicol Sci. 2009 Dec; 112(2):331-43.

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Fontenot HB, Harris AL. The latest advances in hormonal contraception. J Obstet Gynecol Neonatal Nurs. 2008 May-Jun; 37(3):369-74.

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Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments. Breast Cancer Res. 2004; 6(1):R31-7.

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Rice VM. Optimizing the dose of hormone replacement therapy. Int J Fertil Womens Med. 2002 Sep-Oct; 47(5):205-10.

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Montgomery Rice V. Hormone replacement therapy: optimising the dose and route of administration. Drugs Aging. 2002; 19(11):807-18.

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